8A4D
1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with a thiamine analog inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 1-deoxy-D-xylulose-5-phosphate synthase | polymer | 622 | 67223.4 | 6 | UniProt (B7V7R4) Pfam (PF13292) Pfam (PF02779) Pfam (PF02780) | Pseudomonas aeruginosa LESB58 | 1-deoxyxylulose-5-phosphate synthase,DXP synthase,DXPS |
| 2 | G, K, N, S, V... (A, B, C, D, E...) | 2-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]phenyl}ethanol | non-polymer | 243.3 | 6 | Chemie (26G) | |||
| 3 | AA, BA, CA, H, I... (F, A, B, C, D...) | MAGNESIUM ION | non-polymer | 24.3 | 11 | Chemie (MG) | |||
| 4 | EA, J, Q, R, U (F, A, C, D) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) | |||
| 5 | DA, M (F, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | Z (F) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | FA, GA, HA, IA, JA... (A, B, C, D, E...) | water | water | 18.0 | 2103 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 29 - 234 (UniProt: B7V7R4)
A, B, C, D, E, F: 241 - 622 (UniProt: B7V7R4)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Ser 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Ser 12 | - | expression tag |
| Gly 13 | - | expression tag |
| Leu 14 | - | expression tag |
| Val 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Arg 17 | - | expression tag |
| Gly 18 | - | expression tag |
| Ser 19 | - | expression tag |
| Met 20 | - | expression tag |
| Glu 21 | - | expression tag |
| Asn 22 | - | expression tag |
| Leu 23 | - | expression tag |
| Tyr 24 | - | expression tag |
| Phe 25 | - | expression tag |
| Gln 26 | - | expression tag |
| Ser 27 | - | expression tag |
| His 28 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 235 | - | linker |
| Gly 236 | - | linker |
| Gly 237 | - | linker |
| Gly 238 | - | linker |
| Gly 239 | - | linker |
| Gly 240 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 403340.3 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 2014.4 | |
| All* | Total formula weight | 405354.6 |
