1A6I
 
 | | TET REPRESSOR, CLASS D VARIANT | | 分子名称: | TETRACYCLINE REPRESSOR PROTEIN CLASS D | | 著者 | Orth, P, Cordes, F, Schnappinger, D, Hillen, W, Saenger, W, Hinrichs, W. | | 登録日 | 1998-02-25 | | 公開日 | 1999-03-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Conformational changes of the Tet repressor induced by tetracycline trapping.
J.Mol.Biol., 279, 1998
|
|
1ORK
 | | TET REPRESSOR, CLASS D IN COMPLEX WITH 9-(N,N-DIMETHYLGLYCYLAMIDO)-6-DEMETHYL-6-DEOXY-TETRACYCLINE | | 分子名称: | 9-(N,N-DIMETHYLGLYCYLAMIDO)-6-DEOXY-6-DEMETHYL-TETRACYCLINE, MAGNESIUM ION, TETRACYCLINE REPRESSOR | | 著者 | Orth, P, Schnappinger, D, Sum, P.-E, Ellestad, G.A, Hillen, W, Saenger, W, Hinrichs, W. | | 登録日 | 1998-05-21 | | 公開日 | 1999-06-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline.
J.Mol.Biol., 285, 1999
|
|
1SXH
 | | apo structure of B. megaterium transcription regulator | | 分子名称: | Glucose-resistance amylase regulator | | 著者 | Schumacher, M.A, Allen, G.S, Diel, M, Seidel, G, Hillen, W, Brennan, R.G. | | 登録日 | 2004-03-30 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural studies on the apo transcription factor form B. megaterium
Cell(Cambridge,Mass.), 118, 2004
|
|
1SXI
 | | Structure of apo transcription regulator B. megaterium | | 分子名称: | Glucose-resistance amylase regulator, MAGNESIUM ION | | 著者 | Schumacher, M.A, Allen, G.S, Diel, M, Seidel, G, Hillen, W, Brennan, R.G. | | 登録日 | 2004-03-30 | | 公開日 | 2004-10-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural studies on the apo transcription factor form B. megaterium
Cell(Cambridge,Mass.), 118, 2004
|
|
1SXG
 | | Structural studies on the apo transcription factor form B. megaterium | | 分子名称: | 2-PHENYLAMINO-ETHANESULFONIC ACID, Glucose-resistance amylase regulator | | 著者 | Schumacher, M.A, Allen, G.S, Diel, M, Seidel, G, Hillen, W, Brennan, R.G. | | 登録日 | 2004-03-30 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structural studies on the apo transcription factor form B. megaterium
Cell(Cambridge,Mass.), 118, 2004
|
|
1ZVV
 | | Crystal structure of a ccpa-crh-dna complex | | 分子名称: | DNA recognition strand CRE, Glucose-resistance amylase regulator, HPr-like protein crh, ... | | 著者 | Schumacher, M.A, Brennan, R.G, Hillen, W, Seidel, G. | | 登録日 | 2005-06-02 | | 公開日 | 2006-02-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | Phosphoprotein Crh-Ser46-P displays altered binding to CcpA to effect carbon catabolite regulation.
J.Biol.Chem., 281, 2006
|
|
1QPI
 | | CRYSTAL STRUCTURE OF TETRACYCLINE REPRESSOR/OPERATOR COMPLEX | | 分子名称: | DNA (5'-D(*CP*CP*TP*AP*TP*CP*AP*AP*TP*GP*AP*TP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*TP*CP*AP*TP*TP*GP*AP*TP*AP*GP*G)-3'), IMIDAZOLE, ... | | 著者 | Orth, P, Schnappinger, D, Hillen, W, Saenger, W, Hinrichs, W. | | 登録日 | 1999-05-25 | | 公開日 | 2000-02-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system.
Nat.Struct.Biol., 7, 2000
|
|
3FK6
 | | Crystal structure of TetR triple mutant (H64K, S135L, S138I) | | 分子名称: | Tetracycline repressor protein class B from transposon Tn10, Tetracycline repressor protein class D | | 著者 | Klieber, M.A, Scholz, O, Lochner, S, Gmeiner, P, Hillen, W, Muller, Y.A. | | 登録日 | 2008-12-16 | | 公開日 | 2009-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural origins for selectivity and specificity in an engineered bacterial repressor-inducer pair.
Febs J., 276, 2009
|
|
3FK7
 | | Crystal structure of TetR triple mutant (H64K, S135L, S138I) in complex with 4-ddma-atc | | 分子名称: | (4aS,12aS)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide, MAGNESIUM ION, Tetracycline repressor protein class B from transposon Tn10, ... | | 著者 | Klieber, M.A, Scholz, O, Lochner, S, Gmeiner, P, Hillen, W, Muller, Y.A. | | 登録日 | 2008-12-16 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Structural origins for selectivity and specificity in an engineered bacterial repressor-inducer pair.
Febs J., 276, 2009
|
|
3OQN
 | | Structure of ccpa-hpr-ser46-p-gntr-down cre | | 分子名称: | 5'-D(*AP*TP*GP*GP*TP*AP*CP*CP*GP*CP*TP*TP*TP*CP*AP*A)-3', 5'-D(*TP*TP*GP*AP*AP*AP*GP*CP*GP*GP*TP*AP*CP*CP*AP*T)-3', Catabolite control protein A, ... | | 著者 | Schumacher, M.A, Sprehe, M, Bartholomae, M, Hillen, W, Brennan, R.G. | | 登録日 | 2010-09-03 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators.
Nucleic Acids Res., 39, 2011
|
|
3OQO
 | | Ccpa-hpr-ser46p-syn cre | | 分子名称: | 5'-D(*CP*TP*GP*AP*AP*AP*GP*CP*GP*CP*TP*AP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*TP*AP*GP*CP*GP*CP*TP*TP*TP*CP*AP*G)-3', Catabolite control protein A, ... | | 著者 | schumacher, M.A, Sprehe, M, Bartholomae, M, Hillen, W, Brennan, R.G. | | 登録日 | 2010-09-03 | | 公開日 | 2011-10-26 | | 最終更新日 | 2014-04-09 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators.
Nucleic Acids Res., 39, 2011
|
|
3OQM
 | | structure of ccpa-hpr-ser46p-ackA2 complex | | 分子名称: | 5'-D(*TP*TP*GP*AP*TP*AP*AP*CP*GP*CP*TP*TP*AP*CP*AP*A)-3', 5'-D(*TP*TP*GP*TP*AP*AP*GP*CP*GP*TP*TP*AP*TP*CP*AP*A)-3', Catabolite control protein A, ... | | 著者 | Schumacher, M.A, Sprehe, M, Bartholomae, M, Hillen, W, Brennan, R.G. | | 登録日 | 2010-09-03 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators.
Nucleic Acids Res., 39, 2011
|
|
2OEN
 | | Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors glucose-6-phosphate and fructose-1,6-bisphosphate | | 分子名称: | Catabolite control protein, Phosphocarrier protein HPr | | 著者 | Schumacher, M.A, Seidel, G, Hillen, W, Brennan, R.G. | | 登録日 | 2006-12-30 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate.
J.Mol.Biol., 368, 2007
|
|
2VKV
 | | TetR (BD) variant L17G with reverse phenotype | | 分子名称: | 5A,6-ANHYDROTETRACYCLINE, MAGNESIUM ION, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, ... | | 著者 | Resch, M, Striegl, H, Henssler, E.M, Sevvana, M, Egerer-Sieber, C, Schiltz, E, Hillen, W, Muller, Y.A. | | 登録日 | 2008-01-02 | | 公開日 | 2008-07-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | A Protein Functional Leap: How a Single Mutation Reverses the Function of the Transcription Regulator Tetr.
Nucleic Acids Res., 36, 2008
|
|
2NS7
 | | How an in vitro selected peptide mimics the antibiotic tetracycline to induce TET repressor | | 分子名称: | Tetracycline repressor protein | | 著者 | Luckner, S.R, Klotzsche, M, Berens, C, Hillen, W, Muller, Y.A. | | 登録日 | 2006-11-03 | | 公開日 | 2007-07-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | How an agonist peptide mimics the antibiotic tetracycline to induce Tet-repressor
J.Mol.Biol., 368, 2007
|
|
2NZV
 | | Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors G6P and FBP | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, Catabolite control protein, Phosphocarrier protein HPr, ... | | 著者 | Schumacher, M.A, Hillen, W, Brennan, R.G. | | 登録日 | 2006-11-25 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate.
J.Mol.Biol., 368, 2007
|
|
2NS8
 | | How an in vitro selected peptide mimics the antibiotic tetracycline to induce TET repressor | | 分子名称: | 16 residue peptide Tip (Transcription inducing peptide), Tetracycline repressor protein | | 著者 | Luckner, S.R, Klotzsche, M, Berens, C, Hillen, W, Muller, Y.A. | | 登録日 | 2006-11-03 | | 公開日 | 2007-07-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | How an agonist peptide mimics the antibiotic tetracycline to induce Tet-repressor
J.Mol.Biol., 368, 2007
|
|
2NZU
 | | Structural mechanism for the fine-tuning of CcpA function by the small molecule effectors G6P and FBP | | 分子名称: | 6-O-phosphono-beta-D-glucopyranose, Catabolite control protein, Phosphocarrier protein HPr, ... | | 著者 | Schumacher, M.A, Hillen, W, Brennan, R.G. | | 登録日 | 2006-11-25 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Mechanism for the Fine-tuning of CcpA Function by The Small Molecule Effectors Glucose 6-Phosphate and Fructose 1,6-Bisphosphate.
J.Mol.Biol., 368, 2007
|
|
3ZQF
 | | Structure of Tetracycline repressor in complex with antiinducer peptide-TAP1 | | 分子名称: | ANTI-INDUCER PEPTIDE TAP1, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D | | 著者 | Sevvana, M, Goeke, D, Stoeckle, C, Kaspar, D, Grubmueller, S, Goetz, C, Wimmer, C, Berens, C, Klotzsche, M, Muller, Y.A, Hillen, W. | | 登録日 | 2011-06-09 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | An Exclusive Alpha/Beta Code Directs Allostery in Tetr-Peptide Complexes.
J.Mol.Biol., 416, 2012
|
|
3ZQI
 | | Structure of Tetracycline repressor in complex with inducer peptide- TIP2 | | 分子名称: | 1,2-ETHANEDIOL, INDUCER PEPTIDE TIP2, MAGNESIUM ION, ... | | 著者 | Sevvana, M, Goeke, D, Stoeckle, C, Kaspar, D, Grubmueller, S, Goetz, C, Wimmer, C, Berens, C, Klotzsche, M, Muller, Y.A, Hillen, W. | | 登録日 | 2011-06-09 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | An Exclusive Alpha/Beta Code Directs Allostery in Tetr-Peptide Complexes.
J.Mol.Biol., 416, 2012
|
|
3ZQG
 | | Structure of Tetracycline repressor in complex with antiinducer peptide-TAP2 | | 分子名称: | ANTI-INDUCER PEPTIDE TAP2, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, TETRACYCLINE REPRESSOR PROTEIN CLASS D | | 著者 | Sevvana, M, Goeke, D, Stoeckle, C, Kaspar, D, Grubmueller, S, Goetz, C, Wimmer, C, Berens, C, Klotzsche, M, Muller, Y.A, Hillen, W. | | 登録日 | 2011-06-09 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | An Exclusive Alpha/Beta Code Directs Allostery in Tetr-Peptide Complexes.
J.Mol.Biol., 416, 2012
|
|
3ZQH
 | | Structure of Tetracycline repressor in complex with inducer peptide- TIP3 | | 分子名称: | 1,2-ETHANEDIOL, INDUCER PEPTIDE TIP3, TETRACYCLINE REPRESSOR PROTEIN CLASS B FROM TRANSPOSON TN10, ... | | 著者 | Sevvana, M, Goeke, D, Stoeckle, C, Kaspar, D, Grubmueller, S, Goetz, C, Wimmer, C, Berens, C, Klotzsche, M, Muller, Y.A, Hillen, W. | | 登録日 | 2011-06-09 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | An Exclusive Alpha/Beta Code Directs Allostery in Tetr-Peptide Complexes.
J.Mol.Biol., 416, 2012
|
|
2VKE
 | |
2FJ1
 | | Crystal Structure Analysis of Tet Repressor (class D) in Complex with 7-Chlortetracycline-Nickel(II) | | 分子名称: | 7-CHLOROTETRACYCLINE, CHLORIDE ION, NICKEL (II) ION, ... | | 著者 | Orth, P, Saenger, W, Palm, G.J, Hinrichs, W. | | 登録日 | 2005-12-30 | | 公開日 | 2007-01-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Specific binding of divalent metal ions to tetracycline and to the Tet repressor/tetracycline complex.
J.Biol.Inorg.Chem., 13, 2008
|
|
2TCT
 | |
