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7LVN
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Solution structure of tarantula toxin omega-Avsp1a
分子名称: Omega-Avsp1a
著者Chin, Y.K.Y, Herzig, V, King, G.F.
登録日2021-02-26
公開日2022-03-02
最終更新日2023-10-11
実験手法SOLUTION NMR
主引用文献The Tarantula Toxin omega-Avsp1a Specifically Inhibits Human Ca V 3.1 and Ca V 3.3 via the Extracellular S3-S4 Loop of the Domain 1 Voltage-Sensor.
Biomedicines, 10, 2022
5WLX
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BU of 5wlx by Molmil
Solution structure of kappa-theraphotoxin-Aa1a
分子名称: Kappa-theraphotoxin-Aa1a
著者Chin, Y.K.Y, Ma, L, King, G.F.
登録日2017-07-28
公開日2018-08-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Novel venom-derived inhibitors of the human EAG channel, a putative antiepileptic drug target.
Biochem. Pharmacol., 158, 2018
9BFL
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BU of 9bfl by Molmil
Solution structure of the scorpion toxin omega-Buthitoxin-Hf1a
分子名称: Buthitoxin-Hf1a
著者Rosengren, K.J, Payne, C.D.
登録日2024-04-18
公開日2024-06-05
実験手法SOLUTION NMR
主引用文献Novel Scorpion Toxin omega-Buthitoxin-Hf1a Selectively Inhibits Calcium Influx via Ca V 3.3 and Ca V 3.2 and Alleviates Allodynia in a Mouse Model of Acute Postsurgical Pain.
Int J Mol Sci, 25, 2024
6OTA
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BU of 6ota by Molmil
THREE-DIMENSIONAL STRUCTURE IN SOLUTION OF THE RIBBON DISULFIDE ISOMER OF THE NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONIST ALPHA-CONOTOXIN TxIA
分子名称: Alpha-conotoxin TxIA
著者Clark, R.J, Nicke, A.
登録日2019-05-02
公開日2020-05-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural and functional analysis of E. Coli-expressed 4/7 alpha-conotoxin analogues reveals preferential formation of ribbon isomers
To Be Published
6V6T
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Solution structure of delta-theraphotoxin-Hm1b from Heteroscodra maculata
分子名称: Delta-theraphotoxin-Hm1b
著者Chin, Y.K.Y, Chow, C.Y, King, G.F.
登録日2019-12-05
公開日2020-05-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A selective Na V 1.1 activator with potential for treatment of Dravet syndrome epilepsy.
Biochem Pharmacol, 181, 2020
5T4R
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NMR solution structure of the Nav1.7 selective spider venom-derived peptide Pn3a
分子名称: Mu-theraphotoxin-Pn3a
著者Rosengren, K.J, Armstrong, D.A, Vetter, I.
登録日2016-08-30
公開日2017-09-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Pharmacological characterisation of the highly Na V 1.7 selective spider venom peptide Pn3a.
Sci Rep, 7, 2017
6BA3
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NMR structure of U21-hexatoxin-Hi1a toxin from Australian Funnel-web spider Hadronyche infensa
分子名称: U21-hexatoxin-Hi1a
著者Chin, Y.K.-Y, Pineda, S.S, King, G.F.
登録日2017-10-12
公開日2018-10-17
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene.
Proc.Natl.Acad.Sci.USA, 117, 2020
7JPM
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BU of 7jpm by Molmil
The solution structure of omega-theraphotoxin-Pm1b isolated from King Baboon spider
分子名称: Omega-theraphotoxin-Pm1b
著者Chin, Y.K.-Y, Ziegman, R, Alewood, P.F.
登録日2020-08-09
公開日2021-09-08
最終更新日2023-10-11
実験手法SOLUTION NMR
主引用文献Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider.
Proc.Natl.Acad.Sci.USA, 119, 2022
6OHX
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Solution structure of scorpion Hottentotta jayakari venom toxin Hj1a
分子名称: Venom toxin Hj1a
著者Chin, Y.K.-Y, Chow, C.Y, King, G.F.
登録日2019-04-08
公開日2020-02-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Venom Peptides with Dual Modulatory Activity on the Voltage-Gated Sodium Channel NaV1.1 Provide Novel Leads for Development of Antiepileptic Drugs.
Acs Pharmacol Transl Sci, 3, 2020
6OFA
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BU of 6ofa by Molmil
Wasabi Receptor Toxin
分子名称: Wasabi Receptor Toxin
著者Lin King, J.V, Kelly, M.J.S, Julius, D.
登録日2019-03-28
公開日2019-08-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain.
Cell, 178, 2019
5FZW
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High resolution solution NMR structure of the spider venom peptide U3- scytotoxin-Sth1h
分子名称: Venom peptide U3-SYTX-Sth1h
著者Loening, N.M.
登録日2016-03-15
公開日2016-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Characterization of Three Venom Peptides from the Spitting Spider Scytodes Thoracica.
Plos One, 11, 2016
5FZV
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High resolution solution NMR structure of the spider venom peptide U3- scytotoxin-Sth1a
分子名称: Venom peptide U3-SYTX-Sth1a
著者Loening, N.M.
登録日2016-03-15
公開日2016-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Characterization of Three Venom Peptides from the Spitting Spider Scytodes Thoracica.
Plos One, 11, 2016
5FZX
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High resolution solution NMR structure of the spider venom peptide U5- scytotoxin-Sth1a
分子名称: U5-SCYTOTOXIN-STH1A
著者Loening, N.M.
登録日2016-03-15
公開日2016-06-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Characterization of Three Venom Peptides from the Spitting Spider Scytodes Thoracica.
Plos One, 11, 2016
2MF3
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SGTX-Sf1a
分子名称: U2-segestritoxin-Sf1a
著者Mobli, M, Bende, N.S, King, G.F.
登録日2013-10-04
公開日2014-10-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large beta-hairpin loop.
Febs J., 282, 2015
2MI5
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Structure of insect-specific sodium channel toxin mu-Dc1a
分子名称: Mu-diguetoxin-Dc1a
著者Bende, N.S, Mobli, M, King, G.F.
登録日2013-12-08
公開日2014-07-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a.
Nat Commun, 5, 2014
2KSL
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Structure of the insecticidal toxin TaITX-1
分子名称: U1-agatoxin-Ta1a
著者Mobli, M, King, G.F.
登録日2010-01-07
公開日2011-01-19
最終更新日2015-06-24
実験手法SOLUTION NMR
主引用文献Weaponization of a Hormone: Convergent Recruitment of Hyperglycemic Hormone into the Venom of Arthropod Predators
Structure, 2015
2M36
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Solution structure of the insecticidal spider-venom peptide Aps III
分子名称: U2-cyrtautoxin-As1a
著者King, G.F, Bende, N.S, Mobli, M.
登録日2013-01-10
公開日2013-03-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels.
Biochem Pharmacol, 85, 2013
2MPQ
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Solution structure of the sodium channel toxin Hd1a
分子名称: Hd1a
著者Klint, J.K, Mobli, M, King, G.F.
登録日2014-06-01
公開日2015-03-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach.
Br.J.Pharmacol., 172, 2015
2MXM
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NMR solution structure of TRTX-Tp1a from the tarantula Thrixopelma pruriens
分子名称: entity
著者Rosengren, K.
登録日2015-01-08
公開日2015-06-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Identification and Characterization of ProTx-III [ mu-TRTX-Tp1a], a New Voltage-Gated Sodium Channel Inhibitor from Venom of the Tarantula Thrixopelma pruriens.
Mol.Pharmacol., 88, 2015
2NBC
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BU of 2nbc by Molmil
Resonance assignments and structure determination of poneritoxin, omega-PONTX-Ae1a, from Anochetus emarginatus
分子名称: poneritoxin
著者Chin, Y.K.-Y, Touchard, A, King, G.F.
登録日2016-02-03
公開日2017-01-11
実験手法SOLUTION NMR
主引用文献Isolation and characterization of a structurally unique beta-hairpin venom peptide from the predatory ant Anochetus emarginatus.
Biochim.Biophys.Acta, 1860, 2016
2N6R
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NMR structure of spider toxin U4-hexatoxin-Hi1a
分子名称: U4-hexatoxin-Hi1a
著者Pineda, S.S, Chin, Y.K.-Y, King, G.F.
登録日2015-08-28
公開日2016-08-31
最終更新日2023-03-08
実験手法SOLUTION NMR
主引用文献Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene.
Proc.Natl.Acad.Sci.USA, 117, 2020
2MUN
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Solution structure of mu-SLPTX3-Ssm6a
分子名称: Mu-scoloptoxin-Ssm6a
著者Undheim, E.A.B, King, G.F, Mobli, M.
登録日2014-09-13
公開日2015-06-24
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Weaponization of a Hormone: Convergent Recruitment of Hyperglycemic Hormone into the Venom of Arthropod Predators.
Structure, 23, 2015
2N6N
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Structure Determination for spider toxin, U4-agatoxin-Ao1a
分子名称: U4-agatoxin-Ao1a
著者Pineda, S.S, Chin, Y.K.-Y, Mobli, M.S, King, G.F.
登録日2015-08-27
公開日2016-08-31
最終更新日2023-03-08
実験手法SOLUTION NMR
主引用文献Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene.
Proc.Natl.Acad.Sci.USA, 117, 2020
2N8K
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Chemical Shift Assignments and Structure Determination for spider toxin, U33-theraphotoxin-Cg1c
分子名称: U33-theraphotoxin-Cg1b
著者Chin, Y.K.-Y, Pineda, S.S, Mobli, M, King, G.F.
登録日2015-10-20
公開日2016-08-31
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene.
Proc.Natl.Acad.Sci.USA, 117, 2020

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