4ZID
 
 | | Dimeric Hydrogenobacter thermophilus cytochrome c552 obtained from Escherichia coli | | 分子名称: | Cytochrome c-552, HEME C | | 著者 | Hayashi, Y, Yamanaka, M, Nagao, S, Komori, H, Higuchi, Y, Hirota, S. | | 登録日 | 2015-04-28 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Domain swapping oligomerization of thermostable c-type cytochrome in E. coli cells
Sci Rep, 6, 2016
|
|
3VYM
 | | Dimeric Hydrogenobacter thermophilus cytochrome c552 | | 分子名称: | Cytochrome c-552, HEME C | | 著者 | Hayashi, Y, Nagao, S, Osuka, H, Komori, H, Higuchi, Y, Hirota, S. | | 登録日 | 2012-09-28 | | 公開日 | 2012-11-07 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Domain Swapping of the Heme and N-Terminal alpha-Helix in Hydrogenobacter thermophilus Cytochrome c(552) Dimer
Biochemistry, 51, 2012
|
|
2E9L
 | | Crystal Structure of human Cytosolic Neutral beta-Glycosylceramidase (Klotho-related Prote:KLrP) complex with Glucose and fatty acids | | 分子名称: | Cytosolic beta-glucosidase, GLYCEROL, OLEIC ACID, ... | | 著者 | Kakuta, Y, Hayashi, Y, Okino, N, Ito, M. | | 登録日 | 2007-01-25 | | 公開日 | 2007-09-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase.
J.Biol.Chem., 282, 2007
|
|
2E9M
 | | Crystal Structure of human Cytosolic Neutral beta-Glycosylceramidase (Klotho-related Prote:KLrP) complex with Galactose and fatty acids | | 分子名称: | Cytosolic beta-glucosidase, OLEIC ACID, PALMITIC ACID, ... | | 著者 | Kakuta, Y, Hayashi, Y, Okino, N, Ito, M. | | 登録日 | 2007-01-25 | | 公開日 | 2007-09-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase.
J.Biol.Chem., 282, 2007
|
|
1K5O
 | | CPI-17(35-120) deletion mutant | | 分子名称: | CPI-17 | | 著者 | Ohki, S, Eto, M, Kariya, E, Hayano, T, Hayashi, Y, Yazawa, M, Brautigan, D, Kainosho, M. | | 登録日 | 2001-10-11 | | 公開日 | 2002-10-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR Structure of the Myosin Phosphatase Inhibitor Protein CPI-17 Shows Phosphorylation-induced Conformational Changes Responsible for Activation
J.Mol.Biol., 314, 2001
|
|
3CVF
 | | Crystal Structure of the carboxy terminus of Homer3 | | 分子名称: | Homer protein homolog 3 | | 著者 | Hayashi, M.K, Stearns, M.H, Giannini, V, Xu, R.-M, Sala, C, Hayashi, Y. | | 登録日 | 2008-04-18 | | 公開日 | 2009-03-31 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The postsynaptic density proteins Homer and Shank form a polymeric network structure.
Cell(Cambridge,Mass.), 137, 2009
|
|
3CVE
 | | Crystal Structure of the carboxy terminus of Homer1 | | 分子名称: | Homer protein homolog 1 | | 著者 | Hayashi, M.K, Stearns, M.H, Giannini, V, Xu, R.-M, Sala, C, Hayashi, Y. | | 登録日 | 2008-04-18 | | 公開日 | 2009-03-31 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The postsynaptic density proteins Homer and Shank form a polymeric network structure.
Cell(Cambridge,Mass.), 137, 2009
|
|
4XFP
 | | Crystal Structure of Highly Active Mutant of Bacillus sp. TB-90 Urate Oxidase | | 分子名称: | 8-AZAXANTHINE, CHLORIDE ION, SULFATE ION, ... | | 著者 | Hibi, T, Hayashi, Y, Kawamura, A, Itoh, T. | | 登録日 | 2014-12-28 | | 公開日 | 2016-01-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Glycine Substitution of Surface Proline 287 Involves Entropic Enhancement of Bacillus sp. TB-90 Uricase Activity
To be published
|
|
4EBW
 | | Structure of Focal Adhesion Kinase catalytic domain in complex with novel allosteric inhibitor | | 分子名称: | 1-ethyl-8-(4-ethylphenyl)-5-methyl-1,5-dihydropyrazolo[4,3-c][2,1]benzothiazine 4,4-dioxide, Focal adhesion kinase 1 | | 著者 | Iwatani, M, Iwata, H, Okabe, A, Skene, R.J, Tomita, N, Hayashi, Y, Aramaki, Y, Hosfield, D.J, Hori, A, Baba, A, Miki, H. | | 登録日 | 2012-03-25 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Discovery and characterization of novel allosteric FAK inhibitors.
Eur.J.Med.Chem., 61, 2013
|
|
1UIL
 | | Double-stranded RNA-binding motif of Hypothetical protein BAB28848 | | 分子名称: | Double-stranded RNA-binding motif | | 著者 | Nagata, T, Muto, Y, Hayashi, F, Hamana, H, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-07-17 | | 公開日 | 2004-11-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of Double-stranded RNA-binding motif of Hypothetical protein BAB28848
To be Published
|
|
1UHW
 | | Solution structure of the DEP domain of mouse pleckstrin | | 分子名称: | Pleckstrin | | 著者 | Inoue, K, Yoshida, M, Hatta, R, Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Tanaka, A, Osanai, T, Matsuo, Y, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-07-11 | | 公開日 | 2004-01-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the DEP domain of mouse pleckstrin
To be Published
|
|
1UGJ
 | | Solution structure of a murine hypothetical protein from RIKEN cDNA 2310057J16 | | 分子名称: | RIKEN cDNA 2310057J16 protein | | 著者 | Nagashima, T, Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-06-16 | | 公開日 | 2004-08-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a murine hypothetical protein from RIKEN cDNA 2310057J16
To be Published
|
|
1UH6
 | | Solution Structure of the murine ubiquitin-like 5 protein from RIKEN cDNA 0610031K06 | | 分子名称: | ubiquitin-like 5 | | 著者 | Hayashi, F, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-06-25 | | 公開日 | 2003-12-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the murine ubiquitin-like 5 protein from RIKEN cDNA 0610031K06
To be Published
|
|
2ZOX
 | | Crystal Structure of the Covalent Intermediate of Human Cytosolic beta-Glucosidase | | 分子名称: | 4-nitrophenyl alpha-D-glucopyranoside, Cytosolic beta-glucosidase, GLYCEROL, ... | | 著者 | Noguchi, J, Hayashi, Y, Baba, Y, Okino, N, Kimura, M, Ito, M, Kakuta, Y. | | 登録日 | 2008-06-17 | | 公開日 | 2008-09-30 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the covalent intermediate of human cytosolic beta-glucosidase
Biochem.Biophys.Res.Commun., 374, 2008
|
|
3VKK
 | | Crystal Structure Of The Covalent Intermediate Of Human Cytosolic Beta-Glucosidase-mannose complex | | 分子名称: | CHLORIDE ION, Cytosolic beta-glucosidase, GLYCEROL, ... | | 著者 | Noguchi, J, Hayashi, Y, Okino, N, Ito, M, Kimura, M, Kakuta, Y. | | 登録日 | 2011-11-17 | | 公開日 | 2012-11-21 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for inhibition mechanism of human cytosolic beta-glucosidase by monnoside
To be Published
|
|
3WLV
 | | Thermostable urate oxidase from Bacillus sp. TB-90 | | 分子名称: | 8-AZAXANTHINE, CHLORIDE ION, POTASSIUM ION, ... | | 著者 | Hibi, T, Hayashi, Y, Itoh, T. | | 登録日 | 2013-11-14 | | 公開日 | 2014-06-18 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | | 主引用文献 | Intersubunit salt bridges with a sulfate anion control subunit dissociation and thermal stabilization of Bacillus sp. TB-90 urate oxidase.
Biochemistry, 53, 2014
|
|
3AAD
 | | Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction | | 分子名称: | Histone chaperone ASF1A, SULFATE ION, Transcription initiation factor TFIID subunit 1 | | 著者 | Akai, Y, Adachi, N, Hayashi, Y, Eitoku, M, Sano, N, Natsume, R, Kudo, N, Tanokura, M, Senda, T, Horikoshi, M. | | 登録日 | 2009-11-16 | | 公開日 | 2010-04-28 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
7E18
 | | Crystal structure of SAR-CoV-2 3CL protease complex with inhibitor YH-53 | | 分子名称: | 1,2-ETHANEDIOL, N-[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-4-methoxy-1H-indole-2-carboxamide, Replicase polyprotein 1ab | | 著者 | Senda, M, Konno, S, Hayashi, Y, Senda, T. | | 登録日 | 2021-02-01 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents.
J.Med.Chem., 65, 2022
|
|
7E19
 | | Crystal structure of SAR-CoV-2 3CL protease complex with inhibitor SH-5 | | 分子名称: | (phenylmethyl) N-[(2S)-1-[[(2S)-1-[[(2S)-1-(1,3-benzothiazol-2-yl)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]carbamate, 3C-like proteinase | | 著者 | Senda, M, Konno, S, Hayashi, Y, Senda, T. | | 登録日 | 2021-02-01 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents.
J.Med.Chem., 65, 2022
|
|
5ZC6
 | | Solution structure of H-RasT35S mutant protein in complex with KBFM123 | | 分子名称: | 3-oxidanyl-~{N}-[[(2~{R})-oxolan-2-yl]methyl]naphthalene-2-carboxamide, GTPase HRas, MAGNESIUM ION, ... | | 著者 | Matsumoto, S, Hayashi, Y, Hiraga, T, Matsuo, K, Kataoka, T. | | 登録日 | 2018-02-15 | | 公開日 | 2018-09-12 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Basis for Allosteric Inhibition of GTP-Bound H-Ras Protein by a Small-Molecule Compound Carrying a Naphthalene Ring
Biochemistry, 57, 2018
|
|
5Y7O
 | | Crystal structure of folding sensor region of UGGT from Thermomyces dupontii | | 分子名称: | UGGT | | 著者 | Satoh, T, Song, C, Zhu, T, Toshimori, T, Murata, K, Hayashi, Y, Kamikubo, H, Uchihashi, T, Kato, K. | | 登録日 | 2017-08-17 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Visualisation of a flexible modular structure of the ER folding-sensor enzyme UGGT.
Sci Rep, 7, 2017
|
|
5Y7F
 | | Crystal structure of catalytic domain of UGGT (UDP-bound form) from Thermomyces dupontii | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, UGGT, ... | | 著者 | Satoh, T, Song, C, Zhu, T, Toshimori, T, Murata, K, Hayashi, Y, Kamikubo, H, Uchihashi, T, Kato, K. | | 登録日 | 2017-08-17 | | 公開日 | 2017-09-27 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Visualisation of a flexible modular structure of the ER folding-sensor enzyme UGGT.
Sci Rep, 7, 2017
|
|
2ANL
 | | X-ray crystal structure of the aspartic protease plasmepsin 4 from the malarial parasite plasmodium malariae bound to an allophenylnorstatine based inhibitor | | 分子名称: | (4R)-3-{(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-N-(2-methylbenzyl)-1,3-thiazolidine-4-carboxamide, plasmepsin IV | | 著者 | Clemente, J.C, Govindasamy, L, Madabushi, A, Fisher, S.Z, Moose, R.E, Yowell, C.A, Hidaka, K, Kimura, T, Hayashi, Y, Kiso, Y, Agbandje-McKenna, M, Dame, J.B, Dunn, B.M, McKenna, R. | | 登録日 | 2005-08-11 | | 公開日 | 2006-04-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor.
Acta Crystallogr.,Sect.D, 62, 2006
|
|
1UFZ
 | | Solution structure of HBS1-like domain in hypothetical protein BAB28515 | | 分子名称: | Hypothetical protein BAB28515 | | 著者 | He, F, Muto, Y, Hayami, N, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-06-11 | | 公開日 | 2004-08-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of HBS1-like domain in hypothetical protein BAB28515
To be Published
|
|
1UG8
 | | NMR structure of the R3H domain from Poly(A)-specific Ribonuclease | | 分子名称: | Poly(A)-specific Ribonuclease | | 著者 | Nagata, T, Muto, Y, Hayami, N, Uda, H, Shirouzu, M, Terada, T, Kigawa, T, Inoue, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Hirota, H, Yoshida, M, Kobayashi, N, Tanaka, A, Osanai, T, Matsuo, Y, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-06-15 | | 公開日 | 2004-08-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the R3H domain from Poly(A)-specific Ribonuclease
To be Published
|
|
