1ZJW
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![BU of 1zjw by Molmil](/molmil-images/mine/1zjw) | Glutaminyl-tRNA synthetase complexed to glutamine and 2'deoxy A76 glutamine tRNA | 分子名称: | ADENOSINE MONOPHOSPHATE, GLUTAMINE, Glutaminyl-tRNA, ... | 著者 | Gruic-Sovulj, I, Uter, N, Bullock, T, Perona, J.J. | 登録日 | 2005-05-01 | 公開日 | 2005-06-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | tRNA-dependent Aminoacyl-adenylate Hydrolysis by a Nonediting Class I Aminoacyl-tRNA Synthetase. J.Biol.Chem., 280, 2005
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4CQN
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![BU of 4cqn by Molmil](/molmil-images/mine/4cqn) | Crystal structure of the E.coli LeuRS-tRNA complex with the non- cognate isoleucyl adenylate analogue | 分子名称: | ESCHERICHIA COLI TRNA-LEU UAA ISOACCEPTOR, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ... | 著者 | Palencia, A, Cusack, S, Cvetesic, N, Haslaz, I, Gruic-Sovulj, I. | 登録日 | 2014-02-20 | 公開日 | 2014-07-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Physiological Target for Leurs Translational Quality Control is Norvaline Embo J., 33, 2014
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2CJ9
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![BU of 2cj9 by Molmil](/molmil-images/mine/2cj9) | Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with an analog of seryladenylate | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, CHLORIDE ION, SERYL-TRNA SYNTHETASE, ... | 著者 | Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N. | 登録日 | 2006-03-29 | 公開日 | 2006-06-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition Embo J., 25, 2006
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2CJA
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![BU of 2cja by Molmil](/molmil-images/mine/2cja) | Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N. | 登録日 | 2006-03-30 | 公開日 | 2006-06-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition Embo J., 25, 2006
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2CIM
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![BU of 2cim by Molmil](/molmil-images/mine/2cim) | Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase | 分子名称: | CHLORIDE ION, PLATINUM (II) ION, SERYL-TRNA SYNTHETASE, ... | 著者 | Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N. | 登録日 | 2006-03-24 | 公開日 | 2006-06-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition Embo J., 25, 2006
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2CJB
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![BU of 2cjb by Molmil](/molmil-images/mine/2cjb) | Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with serine | 分子名称: | CHLORIDE ION, SERINE, SERYL-TRNA SYNTHETASE, ... | 著者 | Bilokapic, S, Maier, T, Ahel, D, Gruic-Sovulj, I, Soll, D, Weygand-Durasevic, I, Ban, N. | 登録日 | 2006-03-30 | 公開日 | 2006-06-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the Unusual Seryl-tRNA Synthetase Reveals a Distinct Zinc-Dependent Mode of Substrate Recognition Embo J., 25, 2006
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8C9E
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![BU of 8c9e by Molmil](/molmil-images/mine/8c9e) | Priestia megaterium mupirocin-sensitive isoleucyl-tRNA synthetase 1 complexed with an isoleucyl-adenylate analogue | 分子名称: | CHLORIDE ION, Isoleucine--tRNA ligase, LITHIUM ION, ... | 著者 | Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I. | 登録日 | 2023-01-21 | 公開日 | 2023-08-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023
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8C8U
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![BU of 8c8u by Molmil](/molmil-images/mine/8c8u) | Priestia megaterium mupirocin-resistant isoleucyl-tRNA synthetase 2 complexed with mupirocin | 分子名称: | Isoleucine--tRNA ligase, L(+)-TARTARIC ACID, MUPIROCIN, ... | 著者 | Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Gruic-Sovulj, I, Ban, N. | 登録日 | 2023-01-21 | 公開日 | 2023-08-23 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023
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8C9G
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![BU of 8c9g by Molmil](/molmil-images/mine/8c9g) | Priestia megaterium mupirocin-sensitive isoleucyl-tRNA synthetase 1 complexed with mupirocin | 分子名称: | CHLORIDE ION, GLYCEROL, Isoleucine--tRNA ligase, ... | 著者 | Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I. | 登録日 | 2023-01-22 | 公開日 | 2023-08-23 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023
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8C8W
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![BU of 8c8w by Molmil](/molmil-images/mine/8c8w) | Priestia megaterium mupirocin hyper-resistant HIGH motif mutant of type 2 isoleucyl-tRNA synthetase complexed with an isoleucyl-adenylate analogue | 分子名称: | D(-)-TARTARIC ACID, Isoleucine--tRNA ligase, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ... | 著者 | Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I. | 登録日 | 2023-01-21 | 公開日 | 2023-08-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023
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8C9F
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![BU of 8c9f by Molmil](/molmil-images/mine/8c9f) | Priestia megaterium inactive HIGH motif mutant of type1 isoleucyl-tRNA synthetase complexed with an isoleucyl-adenylate analogue. | 分子名称: | CHLORIDE ION, Isoleucine--tRNA ligase, LITHIUM ION, ... | 著者 | Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I. | 登録日 | 2023-01-21 | 公開日 | 2023-08-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023
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8C9D
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![BU of 8c9d by Molmil](/molmil-images/mine/8c9d) | Priestia megaterium W130Q mutant of type 2 isoleucyl-tRNA synthetase complexed with an isoleucyl-adenylate analogue | 分子名称: | D(-)-TARTARIC ACID, Isoleucine--tRNA ligase, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ... | 著者 | Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I. | 登録日 | 2023-01-21 | 公開日 | 2023-08-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023
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8C8V
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![BU of 8c8v by Molmil](/molmil-images/mine/8c8v) | Priestia megaterium mupirocin-resistant isoleucyl-tRNA synthetase 2 with a fully-resolved C-terminal tRNA-binding domain complexed with an isoleucyl-adenylate analogue | 分子名称: | D(-)-TARTARIC ACID, Isoleucine--tRNA ligase, N-[ISOLEUCINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, ... | 著者 | Brkic, A, Leibundgut, M, Jablonska, J, Zanki, V, Car, Z, Petrovic Perokovic, V, Ban, N, Gruic-Sovulj, I. | 登録日 | 2023-01-21 | 公開日 | 2023-08-16 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Antibiotic hyper-resistance in a class I aminoacyl-tRNA synthetase with altered active site signature motif. Nat Commun, 14, 2023
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6GIR
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![BU of 6gir by Molmil](/molmil-images/mine/6gir) | Arabidopsis thaliana cytosolic seryl-tRNA synthetase | 分子名称: | Serine--tRNA ligase, cytoplasmic | 著者 | Kekez, I, Kekez, M, Rokov-Plavec, J, Matkovic-Calogovic, D. | 登録日 | 2018-05-15 | 公開日 | 2019-01-02 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.343 Å) | 主引用文献 | Arabidopsis seryl-tRNA synthetase: the first crystal structure and novel protein interactor of plant aminoacyl-tRNA synthetase. FEBS J., 286, 2019
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5OMW
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![BU of 5omw by Molmil](/molmil-images/mine/5omw) | |
5ONH
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![BU of 5onh by Molmil](/molmil-images/mine/5onh) | Quaternary complex of wild type E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation | 分子名称: | 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, L-leucyl-tRNA(Leu), ... | 著者 | Palencia, A, Cusack, S. | 登録日 | 2017-08-03 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430, 2018
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5ON3
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![BU of 5on3 by Molmil](/molmil-images/mine/5on3) | Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of leucine in the aminoacylation conformation | 分子名称: | (2~{S})-~{N}-[(2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl]-2-azanyl-4-methyl-pentanamide, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... | 著者 | Palencia, A, Cusack, S. | 登録日 | 2017-08-02 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430, 2018
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5ON2
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![BU of 5on2 by Molmil](/molmil-images/mine/5on2) | Quaternary complex of mutant T252A of E. coli leucyl-tRNA synthetase with tRNA(leu), leucyl-adenylate analogue, and post-transfer editing analogue of norvaline in the aminoacylation conformation | 分子名称: | 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... | 著者 | Palencia, A, Cusack, S. | 登録日 | 2017-08-02 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Kinetic Origin of Substrate Specificity in Post-Transfer Editing by Leucyl-tRNA Synthetase. J. Mol. Biol., 430, 2018
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3MF1
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![BU of 3mf1 by Molmil](/molmil-images/mine/3mf1) | Crystal structure of class II aaRS homologue (Bll0957) complexed with an analogue of glycyl adenylate | 分子名称: | 5'-O-(glycylsulfamoyl)adenosine, Bll0957 protein, ZINC ION | 著者 | Weygand-Durasevic, I, Mocibob, M, Ivic, N, Bilokapic, S, Maier, T, Luic, M, Ban, N. | 登録日 | 2010-04-01 | 公開日 | 2010-07-28 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis Proc.Natl.Acad.Sci.USA, 107, 2010
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3MF2
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![BU of 3mf2 by Molmil](/molmil-images/mine/3mf2) | Crystal structure of class II aaRS homologue (Bll0957) complexed with AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Bll0957 protein, GLYCEROL, ... | 著者 | Weygand-Durasevic, I, Mocibob, M, Ivic, N, Bilokapic, S, Maier, T, Luic, M, Ban, N. | 登録日 | 2010-04-01 | 公開日 | 2010-07-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis Proc.Natl.Acad.Sci.USA, 107, 2010
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3MEY
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![BU of 3mey by Molmil](/molmil-images/mine/3mey) | Crystal structure of class II aaRS homologue (Bll0957) complexed with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Bll0957 protein, MAGNESIUM ION, ... | 著者 | Weygand-Durasevic, I, Mocibob, M, Ivic, N, Bilokapic, S, Maier, T, Luic, M, Ban, N. | 登録日 | 2010-04-01 | 公開日 | 2010-07-28 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Homologs of aminoacyl-tRNA synthetases acylate carrier proteins and provide a link between ribosomal and nonribosomal peptide synthesis Proc.Natl.Acad.Sci.USA, 107, 2010
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7NTY
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![BU of 7nty by Molmil](/molmil-images/mine/7nty) | |
7NU1
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![BU of 7nu1 by Molmil](/molmil-images/mine/7nu1) | |
7NU2
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![BU of 7nu2 by Molmil](/molmil-images/mine/7nu2) | Crystal Structure of Neisseria gonorrhoeae LeuRS E169G mutant in Complex with the Reaction Intermediate Leu-AMP | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Leucine--tRNA ligase, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2021-03-11 | 公開日 | 2022-08-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip. Commun Biol, 5, 2022
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7NU9
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![BU of 7nu9 by Molmil](/molmil-images/mine/7nu9) | Crystal Structure of Neisseria gonorrhoeae LeuRS in Complex with ATP and L-leucinol | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-4-METHYL-PENTAN-1-OL, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Pang, L, Strelkov, S.V, Weeks, S.D. | 登録日 | 2021-03-11 | 公開日 | 2022-08-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip. Commun Biol, 5, 2022
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