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6MYY
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BU of 6myy by Molmil
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 3 Fabs bound, sharpened map
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ...
著者Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D.
登録日2018-11-02
公開日2018-11-14
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
6MZJ
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BU of 6mzj by Molmil
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ...
著者Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D.
登録日2018-11-05
公開日2018-11-14
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
3G20
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BU of 3g20 by Molmil
Crystal structure of the major pseudopilin from the type 2 secretion system of enterohaemorrhagic Escherichia coli
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, CALCIUM ION, GLYCEROL, ...
著者Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J.
登録日2009-01-30
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
3FU1
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BU of 3fu1 by Molmil
Crystal structure of the major pseudopilin from the type 2 secretion system of Vibrio cholerae
分子名称: CALCIUM ION, General secretion pathway protein G, ZINC ION
著者Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J.
登録日2009-01-13
公開日2009-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
3GN9
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BU of 3gn9 by Molmil
Crystal structure of the major pseudopilin from the type 2 secretion system of Vibrio vulnificus
分子名称: CALCIUM ION, D-MALATE, Type II secretory pathway, ...
著者Korotkov, K.V, Gray, M.D, Kreger, A, Turley, S, Sandkvist, M, Hol, W.G.J.
登録日2009-03-16
公開日2009-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Calcium is essential for the major pseudopilin in the type 2 secretion system.
J.Biol.Chem., 284, 2009
7RDW
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BU of 7rdw by Molmil
Crystal Structure of FH1 Fab bound to HXb2 HIV-1 gp120 core
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AMMONIUM ION, ...
著者Weidle, C, Pancera, M.
登録日2021-07-12
公開日2022-05-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain.
Sci Adv, 8, 2022
6MFT
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BU of 6mft by Molmil
Crystal structure of glycosylated 426c HIV-1 gp120 core G459C in complex with glVRC01 A60C heavy chain
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Weidle, C, Pancera, M, Stamatatos, L, Gray, M.
登録日2018-09-12
公開日2018-11-14
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.315 Å)
主引用文献Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
5I9Q
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BU of 5i9q by Molmil
Crystal structure of 3BNC55 Fab in complex with 426c.TM4deltaV1-3 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC55 Fab heavy chain, ...
著者Scharf, L, Chen, C, Bjorkman, P.J.
登録日2016-02-20
公開日2016-05-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5IGX
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BU of 5igx by Molmil
Crystal structure of NIH45-46 Fab germline precursor in complex with 426c.TM1deltaV1-3 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.TM1deltaV1-3 gp120, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scharf, L, Bjorkman, P.J.
登録日2016-02-28
公開日2016-04-06
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
6VRQ
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BU of 6vrq by Molmil
Crystal structure of gl12A21 Fab in complex with anti-idiotypic iv12 Fab
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Aljedani, S.S, Weidle, C, Pancera, M.
登録日2020-02-08
公開日2021-02-17
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell Rep, 35, 2021
6XOC
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BU of 6xoc by Molmil
Crystal structure of glVRC01 Fab in complex with anti-idiotypic iv4 Fab
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Aljedani, S.S, Weidle, C, Pancera, M.
登録日2020-07-06
公開日2021-03-31
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell Rep, 35, 2021
5F7E
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BU of 5f7e by Molmil
Crystal structure of germ-line precursor of 3BNC60 Fab
分子名称: Fab heavy chain, Fab light chain
著者Sievers, S.A, Scharf, L, Jiang, S, Bjorkman, P.J.
登録日2015-12-08
公開日2016-04-06
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
6OL5
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BU of 6ol5 by Molmil
Structure of iglb12 Fab in complex with anti-idiotype ib3 Fab
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, AMMONIUM ION, CHLORIDE ION, ...
著者Weidle, C, Pancera, M.
登録日2019-04-15
公開日2019-07-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
6OL6
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BU of 6ol6 by Molmil
Structure of iglb12 scFv in complex with anti-idiotype ib2 Fab
分子名称: CHLORIDE ION, ib2 Heavy Chain, ib2 Light Chain, ...
著者Weidle, C, Pancera, M, Gewe, M.
登録日2019-04-15
公開日2019-07-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
5FEC
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BU of 5fec by Molmil
Crystal structure of 3BNC60 Fab germline precursor in complex with 426c.TM4deltaV1-3 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.TM4deltaV1-3 gp120, ...
著者Scharf, L, Bjorkman, P.J.
登録日2015-12-16
公開日2016-05-04
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
5FA2
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BU of 5fa2 by Molmil
Crystal structure of 426c.TM4deltaV1-3 p120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, THIOCYANATE ION, ...
著者Scharf, L, Bjorkman, P.J.
登録日2015-12-10
公開日2016-04-06
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for germline antibody recognition of HIV-1 immunogens.
Elife, 5, 2016
6OL7
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BU of 6ol7 by Molmil
Crystal structure of glVRC01 scFv in complex with anti-idiotype iv8 scFv
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Weidle, C, Pancera, M.
登録日2019-04-15
公開日2019-07-24
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.419 Å)
主引用文献Anti-idiotypic antibodies elicit anti-HIV-1-specific B cell responses.
J.Exp.Med., 216, 2019
4RX4
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BU of 4rx4 by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC134 in complex with HIV-1 clade A Q842.d12 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC134 Heavy chain, ...
著者Zhou, T, Acharya, P, Moquin, S, Kwong, P.D.
登録日2014-12-08
公開日2015-07-01
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
4RWY
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BU of 4rwy by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Acharya, P, Luongo, T.S, Kwong, P.D.
登録日2014-12-08
公開日2015-07-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.128 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
7JLN
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BU of 7jln by Molmil
Crystal structure of glVRC01 Fab in complex with anti-idiotype iv9 Fab
分子名称: AMMONIUM ION, SODIUM ION, glVRC01 Heavy Chain, ...
著者Weidle, C, Pancera, M.
登録日2020-07-30
公開日2021-03-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell Rep, 35, 2021
7JLK
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BU of 7jlk by Molmil
Crystal structure of glVRC01 Fab in complex with anti-idiotype iv1 scFv
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Weidle, C, Pancera, M.
登録日2020-07-29
公開日2021-03-31
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies.
Cell Rep, 35, 2021
6C5V
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BU of 6c5v by Molmil
An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab AMMO1 heavy chain, Antibody Fab AMMO1 light chain, ...
著者Snijder, J, Ortego, M.S, Weidle, C, Stuart, A.B, Gray, M.A, McElrath, M.J, Pancera, M, Veesler, D, McGuire, A.T, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-01-16
公開日2018-05-02
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
6BLA
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BU of 6bla by Molmil
Structure of AMM01 Fab, an anti EBV gH/gL neutralizing antibody
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AMM01 Fab Heavy chain, ...
著者Pancera, M, Weidle, C, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2017-11-09
公開日2018-04-25
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus.
Immunity, 48, 2018
8DG8
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BU of 8dg8 by Molmil
Cryo-EM Structure of HPIV3 prefusion F trimer in complex with 3x1 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3x1 monoclonal antibody, VH region, ...
著者Rodarte, J.V, Pancera, M.
登録日2022-06-23
公開日2023-02-22
最終更新日2024-11-20
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Cross-protective antibodies against common endemic respiratory viruses.
Nat Commun, 14, 2023
8DG9
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BU of 8dg9 by Molmil
Cryo-EM Structure of RSV prefusion F trimer in complex with three MxR Fabs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, mAb MxR Heavy Chain, ...
著者Rodarte, J.V, Pancera, M.
登録日2022-06-23
公開日2023-02-22
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.24 Å)
主引用文献Cross-protective antibodies against common endemic respiratory viruses.
Nat Commun, 14, 2023

 

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