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2KYM
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BU of 2kym by Molmil
Solution structure of the Bem1p SH3-CI domain from L.elongisporus in complex with Ste20p peptide
分子名称: Bud emergence protein 1, Peptide form Serine/threonine-protein kinase STE20
著者Gorelik, M, Muhandiram, R, Davidson, A.R.
登録日2010-06-02
公開日2010-06-23
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of an unusual SH3 domain from the fungal scaffold protein, Bem1p
To be Published
2LCS
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BU of 2lcs by Molmil
Yeast Nbp2p SH3 domain in complex with a peptide from Ste20p
分子名称: NAP1-binding protein 2, Serine/threonine-protein kinase STE20
著者Gorelik, M, Davidson, A.R.
登録日2011-05-07
公開日2012-02-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Distinct Peptide Binding Specificities of Src Homology 3 (SH3) Protein Domains Can Be Determined by Modulation of Local Energetics across the Binding Interface.
J.Biol.Chem., 287, 2012
2FA1
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BU of 2fa1 by Molmil
Crystal structure of PhnF C-terminal domain
分子名称: Probable transcriptional regulator phnF, beta-D-fructopyranose
著者Lunin, V.V, Nocek, B.P, Gorelik, M, Skarina, T, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG)
登録日2005-12-06
公開日2006-01-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural characterization of GntR/HutC family signaling domain.
Protein Sci., 15, 2006
5IBK
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BU of 5ibk by Molmil
Skp1-F-box in complex with a ubiquitin variant
分子名称: F-box/WD repeat-containing protein 7, Polyubiquitin-B, S-phase kinase-associated protein 1,S-phase kinase-associated protein 1
著者Orlicky, S, Sicheri, F.
登録日2016-02-22
公開日2016-03-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface.
Proc.Natl.Acad.Sci.USA, 113, 2016
6BVA
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BU of 6bva by Molmil
Ubiquitin Variant (UbV.Fl10.1) bound to a human Skp1-Fbl10 fragment complex.
分子名称: Lysine-specific demethylase 2B, Polyubiquitin-B, S-phase kinase-associated protein 1
著者Manczyk, N, Sicheri, F.
登録日2017-12-12
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6BYH
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BU of 6byh by Molmil
Ubiquitin Variant (UbV.Fl11.1) bound to a human Skp1-Fbl11 fragment complex.
分子名称: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
著者Manczyk, N, Sicheri, F.
登録日2017-12-20
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
6C16
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BU of 6c16 by Molmil
Ubiquitin variant (UbV.Fbl10.1) bound to a human Skp1-Fbl11 fragment complex.
分子名称: Lysine-specific demethylase 2A, Polyubiquitin-B, S-phase kinase-associated protein 1
著者Manczyk, N, Sicheri, F.
登録日2018-01-04
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献A Structure-Based Strategy for Engineering Selective Ubiquitin Variant Inhibitors of Skp1-Cul1-F-Box Ubiquitin Ligases.
Structure, 26, 2018
7KMK
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BU of 7kmk by Molmil
cryo-EM structure of SARS-CoV-2 spike in complex with Fab 15033-7, two RBDs bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033-7 heavy chain, ...
著者Li, Z, Rini, J.M.
登録日2020-11-03
公開日2021-02-10
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021
7KLG
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BU of 7klg by Molmil
SARS-CoV-2 RBD in complex with Fab 15033
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033 heavy chain, Fab 15033 light chain, ...
著者Li, Z, Rini, J.M.
登録日2020-10-30
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021
7KML
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BU of 7kml by Molmil
cryo-EM structure of SARS-CoV-2 spike in complex with Fab 15033-7, three RBDs bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033-7 heavy chain, ...
著者Li, Z, Rini, J.M.
登録日2020-11-03
公開日2021-02-10
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021
7KLH
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BU of 7klh by Molmil
SARS-CoV-2 RBD in complex with Fab 15033-7
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033-7 heavy chain, Fab 15033-7 light chain, ...
著者Li, Z, Rini, J.M.
登録日2020-10-30
公開日2021-02-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021
8TV1
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BU of 8tv1 by Molmil
Structure of the EphA2 LBDCRD bound to FabS1C_L1
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ephrin type-A receptor 2, ...
著者Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
登録日2023-08-17
公開日2024-06-26
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Synthetic Antibodies targeting EPHA2 Induce Diverse Signaling-Competent Clusters with Differential Activation
To be published
8TRV
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BU of 8trv by Molmil
Structure of the EphA2 LBDCRD bound to FabS1C_C1
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Ephrin type-A receptor 2, ...
著者Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
登録日2023-08-10
公開日2024-07-17
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Synthetic Antibodies targeting EPHA2 Induce Diverse Signaling-Competent Clusters with Differential Activation
To be Published
7OOI
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BU of 7ooi by Molmil
Anti-EphA1 JD1 VH domain
分子名称: JD1 VH domain, SULFATE ION
著者Ereno-Orbea, J, Nilvebrant, J, Sidhu, S, Julien, J.P.
登録日2021-05-27
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains.
J.Mol.Biol., 433, 2021
7OMN
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BU of 7omn by Molmil
Anti-EphA1 JD1-1 VH domain
分子名称: GLYCEROL, IMIDAZOLE, JD1-1 VH domain
著者Ereno Orbea, J, Nilvebrant, J, Sidhu, S, Julien, J.P.
登録日2021-05-24
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Systematic Engineering of Optimized Autonomous Heavy-Chain Variable Domains.
J.Mol.Biol., 433, 2021
7KXJ
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BU of 7kxj by Molmil
SARS-CoV-2 spike protein in complex with Fab 15033-7, 3-"up", asymmetric
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033-7 heavy chain, ...
著者Li, Z, Rini, J.
登録日2020-12-04
公開日2021-02-03
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021
7KXK
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BU of 7kxk by Molmil
SARS-CoV-2 spike protein in complex with Fab 15033-7, 2-"up"-1-"down" conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033-7 heavy chain, ...
著者Li, Z, Rini, J.
登録日2020-12-04
公開日2021-02-03
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021

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件を2024-07-17に公開中

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