6DHB
| Crystal structure of the human TIM-3 with bound Calcium | 分子名称: | 1,2-ETHANEDIOL, BENZOIC ACID, CALCIUM ION, ... | 著者 | Gandhi, A.K, Kim, W.M, Huang, Y.H, Bonsor, D, Sundberg, E, Sun, Z.-Y, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2018-05-19 | 公開日 | 2018-12-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3. Sci Rep, 8, 2018
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7RPP
| Crystal structure of human CEACAM1 with GFCC' and ABED face | 分子名称: | 1,2-ETHANEDIOL, Carcinoembryonic antigen-related cell adhesion molecule 1 | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Petsko, G.A, Blumberg, R.S. | 登録日 | 2021-08-04 | 公開日 | 2022-08-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural analysis of human CEACAM1 oligomerization. Commun Biol, 5, 2022
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6XNT
| Crystal structure of I91A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, octyl beta-D-glucopyranoside | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-04 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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6XNW
| Crystal structure of V39A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, NICKEL (II) ION | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-04 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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6XO1
| Crystal structure of N97A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-05 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.758 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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6XNO
| Crystal structure of E99A mutant of human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside | 著者 | Gandhi, A.K, Kim, W.M, Sun, Z.-Y, Huang, Y.H, Bonsor, D, Petsko, G.A, Kuchroo, V, Blumberg, R.S. | 登録日 | 2020-07-03 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium. Commun Biol, 4, 2021
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4EOH
| Crystal Structure of Human PL Kinase with bound Theophylline | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Pyridoxal Kinase, SODIUM ION, ... | 著者 | Safo, M.K, Gandhi, A.K, Musayev, F.N. | 登録日 | 2012-04-14 | 公開日 | 2012-05-02 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition. Plos One, 7, 2012
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4EN4
| Crystal Structure of the Ternary Human PL Kinase-Ginkgotoxin-MgATP Complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(hydroxymethyl)-4-(methoxymethyl)-2-methylpyridin-3-ol, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Safo, M.K, Musayev, F.N, Gandhi, A.K. | 登録日 | 2012-04-12 | 公開日 | 2012-05-02 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition. Plos One, 7, 2012
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3FHY
| Crystal structure of D235N mutant of human pyridoxal kinase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Safo, M.K, Gandhi, A.K, Musayev, F.N, Ghatge, M, Di Salvo, M.L, Schirch, V. | 登録日 | 2008-12-10 | 公開日 | 2008-12-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinase. Biochem.Biophys.Res.Commun., 381, 2009
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3FHX
| Crystal structure of D235A mutant of human pyridoxal kinase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-HYDROXY-5-(HYDROXYMETHYL)-2-METHYLISONICOTINALDEHYDE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Safo, M.K, Gandhi, A.K, Musayev, F.N, Ghatge, M, Di Salvo, M.L, Schirch, V. | 登録日 | 2008-12-10 | 公開日 | 2008-12-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinase. Biochem.Biophys.Res.Commun., 381, 2009
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3KEU
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6NHA
| Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ... | 著者 | Blumberg, R.S, Cheung, J, Mahmood, A, Gandhi, A.K. | 登録日 | 2018-12-21 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.381 Å) | 主引用文献 | Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. Sci Adv, 5, 2019
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5DZL
| Crystal structure of the protein human CEACAM1 | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1 | 著者 | Huang, Y.H, Russell, A, Gandhi, A.K, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. | 登録日 | 2015-09-25 | 公開日 | 2015-10-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4006 Å) | 主引用文献 | CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
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2YXT
| Human Pyridoxal Kinase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHATE ION, Pyridoxal kinase, ... | 著者 | Safo, M.K, Musayev, F.N, Ko, T.P, Schirch, V. | 登録日 | 2007-04-27 | 公開日 | 2008-03-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation. Protein Sci., 16, 2007
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2YXU
| Human Pyridoxal Kinase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Safo, M.K, Musayev, F.N, Ko, T.P, Schirch, V. | 登録日 | 2007-04-27 | 公開日 | 2008-03-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation. Protein Sci., 16, 2007
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4QXW
| Crystal structure of the human CEACAM1 membrane distal amino terminal (N)-domain | 分子名称: | Carcinoembryonic antigen-related cell adhesion molecule 1, MALONIC ACID, octyl beta-D-glucopyranoside | 著者 | Huang, Y.H, Gandhi, A.K, Russell, A, Kondo, Y, Chen, Q, Petsko, G.A, Blumberg, R.S. | 登録日 | 2014-07-22 | 公開日 | 2014-11-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | CEACAM1 regulates TIM-3-mediated tolerance and exhaustion. Nature, 517, 2015
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4RJY
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3IC2
| Crystal Structure of liganded hemoglobin in complex with a potent antisickling agent, INN-266 | 分子名称: | 4-[(5-methoxy-2-methylphenoxy)methyl]pyridine, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | 著者 | Safo, M.K, Musayev, F.N, Gandhi, A.K, Jorge, P. | 登録日 | 2009-07-17 | 公開日 | 2009-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and in Vitro Chracterization of Pyridyl Derivatives of Benzaldehydes: Highly Potent Antisickling Agents To be Published
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3IC0
| Crystal Structure of liganded hemoglobin in complex with a potent antisickling agent, INN-298 | 分子名称: | 2-[(2-methoxy-5-methylphenoxy)methyl]pyridine, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | 著者 | Safo, M.K, Musayev, F.N, Gandhi, A.K, Jorge, P. | 登録日 | 2009-07-17 | 公開日 | 2009-07-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and in Vitro Chracterization of Pridyl Derivatives of Benzaldehydes: Highly Potent Antisickling Agents To be Published
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