Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7D56
DownloadVisualize
BU of 7d56 by Molmil
Structure of the peptidylarginine deiminase type III (PAD3) in complex with Cl-amidine
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Funabashi, K, Unno, M.
登録日2020-09-25
公開日2021-06-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.175 Å)
主引用文献Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design.
Arch.Biochem.Biophys., 708, 2021
7D8N
DownloadVisualize
BU of 7d8n by Molmil
Structure of the inactive form of wild-type peptidylarginine deiminase type III (PAD3) crystallized under the condition with high concentrations of Ca2+
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Funabashi, K, Sawata, M, Unno, M.
登録日2020-10-08
公開日2021-06-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.753 Å)
主引用文献Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design.
Arch.Biochem.Biophys., 708, 2021
3A60
DownloadVisualize
BU of 3a60 by Molmil
Crystal structure of unphosphorylated p70S6K1 (Form I)
分子名称: Ribosomal protein S6 kinase beta-1, STAUROSPORINE
著者Sunami, T, Byrne, N, Diehl, R.E, Funabashi, K, Hall, D.L, Ikuta, M, Patel, S.B, Shipman, J.M, Smith, R.F, Takahashi, I, Zugay-Murphy, J, Iwasawa, Y, Lumb, K.J, Munshi, S.K, Sharma, S.
登録日2009-08-17
公開日2009-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of human p70 ribosomal S6 kinase-1 regulation by activation loop phosphorylation.
J.Biol.Chem., 285, 2010
3A62
DownloadVisualize
BU of 3a62 by Molmil
Crystal structure of phosphorylated p70S6K1
分子名称: MANGANESE (II) ION, Ribosomal protein S6 kinase beta-1, STAUROSPORINE
著者Sunami, T, Byrne, N, Diehl, R.E, Funabashi, K, Hall, D.L, Ikuta, M, Patel, S.B, Shipman, J.M, Smith, R.F, Takahashi, I, Zugay-Murphy, J, Iwasawa, Y, Lumb, K.J, Munshi, S.K, Sharma, S.
登録日2009-08-18
公開日2009-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis of human p70 ribosomal S6 kinase-1 regulation by activation loop phosphorylation.
J.Biol.Chem., 285, 2010
3A61
DownloadVisualize
BU of 3a61 by Molmil
Crystal structure of unphosphorylated p70S6K1 (Form II)
分子名称: Ribosomal protein S6 kinase beta-1, STAUROSPORINE
著者Sunami, T, Byrne, N, Diehl, R.E, Funabashi, K, Hall, D.L, Ikuta, M, Patel, S.B, Shipman, J.M, Smith, R.F, Takahashi, I, Zugay-Murphy, J, Iwasawa, Y, Lumb, K.J, Munshi, S.K, Sharma, S.
登録日2009-08-18
公開日2009-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.43 Å)
主引用文献Structural basis of human p70 ribosomal S6 kinase-1 regulation by activation loop phosphorylation.
J.Biol.Chem., 285, 2010
7D5V
DownloadVisualize
BU of 7d5v by Molmil
Structure of the C646A mutant of peptidylarginine deiminase type III (PAD3)
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Protein-arginine deiminase type-3
著者Akimoto, M, Mashimo, R, Unno, M.
登録日2020-09-28
公開日2021-06-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design.
Arch.Biochem.Biophys., 708, 2021
7DAN
DownloadVisualize
BU of 7dan by Molmil
Structure of the Ca2+-bound wild-type peptidylarginine deiminase type III (PAD3)
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Sawata, M, Unno, M.
登録日2020-10-16
公開日2021-06-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design.
Arch.Biochem.Biophys., 708, 2021
7D5R
DownloadVisualize
BU of 7d5r by Molmil
Structure of the Ca2+-bound C646A mutant of peptidylarginine deiminase type III (PAD3)
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Mashimo, R, Akimoto, M, Unno, M.
登録日2020-09-28
公開日2021-06-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.148 Å)
主引用文献Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design.
Arch.Biochem.Biophys., 708, 2021
7D4Y
DownloadVisualize
BU of 7d4y by Molmil
Structure of human wild-type peptidylarginine deiminase type III (PAD3)
分子名称: Protein-arginine deiminase type-3
著者Unno, M.
登録日2020-09-24
公開日2021-06-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.962 Å)
主引用文献Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design.
Arch.Biochem.Biophys., 708, 2021
5ZR3
DownloadVisualize
BU of 5zr3 by Molmil
Crystal structure of Hsp90-alpha N-terminal domain in complex with 4-(3-isopropyl-4-(4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)-3-methylbenzamide
分子名称: 3-methyl-4-{4-[4-(1-methyl-1H-pyrazol-4-yl)-1H-imidazol-1-yl]-3-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl}benzamide, Heat shock protein HSP 90-alpha
著者Uno, T, Chong, K.T, Suzuki, T.
登録日2018-04-23
公開日2019-01-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovery of 3-Ethyl-4-(3-isopropyl-4-(4-(1-methyl-1 H-pyrazol-4-yl)-1 H-imidazol-1-yl)-1 H-pyrazolo[3,4- b]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor.
J. Med. Chem., 62, 2019

224572

件を2024-09-04に公開中

PDB statisticsPDBj update infoContact PDBjnumon