3NGV
 
 | | Crystal structure of AnSt-D7L1 | | 分子名称: | D7 protein, GLYCEROL, SULFATE ION | | 著者 | Andersen, J.F, Alvarenga, P.H, Francischetti, I.M, Ribeiro, J.M, Calvo, E. | | 登録日 | 2010-06-13 | | 公開日 | 2010-12-29 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | The function and three-dimensional structure of a thromboxane a(2)/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite.
Plos Biol., 8, 2010
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3NHI
 | | Crystal structure of the AnSt-D7L1-leukotriene C4 complex | | 分子名称: | (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid, D7 protein, GLYCEROL, ... | | 著者 | Andersen, J.F, Alvarenga, P.H, Francischetti, I.M, Calvo, E, Sa-Nunes, A, Ribeiro, J.M. | | 登録日 | 2010-06-14 | | 公開日 | 2010-12-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | The function and three-dimensional structure of a thromboxane a(2)/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite.
Plos Biol., 8, 2010
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3NHT
 | | Crystal structure of the AnSt-D7L1-U46619 complex | | 分子名称: | (5E)-7-{6-[(1E)-3-HYDROXYOCT-1-ENYL]-2-OXABICYCLO[2.2.1]HEPT-5-YL}HEPT-5-ENOIC ACID, D7 protein, SULFATE ION | | 著者 | Andersen, J.F, Alvarenga, P.H, Francischetti, I.M, Calvo, E, Sa-Nunes, A, Ribeiro, J.M. | | 登録日 | 2010-06-14 | | 公開日 | 2010-12-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The function and three-dimensional structure of a thromboxane a(2)/cysteinyl leukotriene-binding protein from the saliva of a mosquito vector of the malaria parasite.
Plos Biol., 8, 2010
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6NAN
 | | NMR structure determination of Ixolaris and Factor X interaction reveals a noncanonical mechanism of Kunitz inhibition | | 分子名称: | Ixolaris | | 著者 | De Paula, V.S, Sgourakis, N.G, Francischetti, I.M.B, Almeida, F.C.L, Monteiro, R.Q, Valente, A.P. | | 登録日 | 2018-12-06 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition.
Blood, 134, 2019
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4TPV
 | | Crystal Structure of Hookworm Platelet Inhibitor | | 分子名称: | GLYCEROL, Platelet inhibitor | | 著者 | Andersen, J.F, Ma, D, Francischetti, I. | | 登録日 | 2014-06-09 | | 公開日 | 2015-04-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The structure of hookworm platelet inhibitor (HPI), a CAP superfamily member from Ancylostoma caninum.
Acta Crystallogr.,Sect.F, 71, 2015
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4JD9
 | | Contact pathway inhibitor from a sand fly | | 分子名称: | 14.5 kDa salivary protein, SULFATE ION | | 著者 | Andersen, J.F, Xu, X, Alvarenga, P. | | 登録日 | 2013-02-24 | | 公開日 | 2013-10-16 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | | 主引用文献 | Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate.
Arterioscler Thromb Vasc Biol, 33, 2013
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3NDA
 | | Crystal structure of serpin from tick Ixodes ricinus | | 分子名称: | PENTAETHYLENE GLYCOL, Serpin-2 | | 著者 | Rezacova, P, Kovarova, Z, Chmelar, J, Mares, M. | | 登録日 | 2010-06-07 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation.
Blood, 117, 2011
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3U3L
 | | Crystal structure of the selenomethionine derivative of tablysin-15 | | 分子名称: | CITRIC ACID, PALMITIC ACID, PRASEODYMIUM ION, ... | | 著者 | Andersen, J.F, Xu, X, Ribeiro, J.M. | | 登録日 | 2011-10-06 | | 公開日 | 2012-02-15 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain.
J.Biol.Chem., 287, 2012
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3U3U
 | | Crystal structure of the tablysin-15-leukotriene E4 complex | | 分子名称: | (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid, CITRIC ACID, PRASEODYMIUM ION, ... | | 著者 | Andersen, J.F. | | 登録日 | 2011-10-06 | | 公開日 | 2012-02-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain.
J.Biol.Chem., 287, 2012
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3U3N
 | | Crystal structure of tablysin-15 | | 分子名称: | CITRIC ACID, PALMITIC ACID, PRASEODYMIUM ION, ... | | 著者 | Andersen, J.F. | | 登録日 | 2011-10-06 | | 公開日 | 2012-02-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | | 主引用文献 | Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain.
J.Biol.Chem., 287, 2012
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8EOK
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8ENU
 | | Structure of the C3bB proconvertase in complex with lufaxin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ... | | 著者 | Andersen, J.F, Lei, H. | | 登録日 | 2022-09-30 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism.
Blood, 141, 2023
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8EO2
 | | Lufaxin a bifunctional inhibitor of complement and coagulation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... | | 著者 | Andersen, J.F, Strayer, E.C. | | 登録日 | 2022-10-01 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism.
Blood, 141, 2023
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7TX8
 | | Long form D7 protein from Anopheles darlingi with U46619 and serotonin bound | | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Long form D7 salivary protein, SEROTONIN | | 著者 | Andersen, J.F, Alvarenga, P.H. | | 登録日 | 2022-02-08 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes.
Insect Biochem.Mol.Biol., 146, 2022
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7TVY
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7TVC
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7U1N
 | | Crystal structure of the Anopheles darlingi AD-118 long form D7 salivary protein | | 分子名称: | 1,2-ETHANEDIOL, 2-(2-METHOXYETHOXY)ETHANOL, 2-ETHOXYETHANOL, ... | | 著者 | Alvarenga, P.H, Gittis, A.G, Garboczi, D.N, Andersen, J.F. | | 登録日 | 2022-02-21 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes.
Insect Biochem.Mol.Biol., 146, 2022
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