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7OTI
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BU of 7oti by Molmil
Structure of ABCB1/P-glycoprotein in apo state
分子名称: Multidrug resistance protein 1A
著者Ford, R.C, Barbieri, A, Thonghin, N, Shafi, T, Prince, S.M, Collins, R.F.
登録日2021-06-10
公開日2021-12-08
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure of ABCB1/P-Glycoprotein in the Presence of the CFTR Potentiator Ivacaftor.
Membranes (Basel), 11, 2021
7OTG
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BU of 7otg by Molmil
Structure of ABCB1/P-glycoprotein in the presence of the CFTR potentiator ivacaftor
分子名称: Multidrug resistance protein 1A, N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
著者Ford, R.C, Barbieri, A, Thonghin, N, Shafi, T, Prince, S.M, Collins, R.F.
登録日2021-06-10
公開日2021-12-08
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Structure of ABCB1/P-Glycoprotein in the Presence of the CFTR Potentiator Ivacaftor.
Membranes (Basel), 11, 2021
5NBZ
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BU of 5nbz by Molmil
Wzz dodecamer fitted by MDFF to the Wzz experimental map from cryo-EM
分子名称: WzzB
著者Ford, R.C, Kargas, V, Collins, R.F, Whitfield, C, Clarke, B.R, Siebert, A, Bond, P.J, Clare, D.K.
登録日2017-03-02
公開日2017-04-05
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Full-length, Oligomeric Structure of Wzz Determined by Cryoelectron Microscopy Reveals Insights into Membrane-Bound States.
Structure, 25, 2017
6Q81
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BU of 6q81 by Molmil
Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state
分子名称: ADENOSINE-5'-DIPHOSPHATE, P-glycoprotein (ABCB1)
著者Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A.
登録日2018-12-13
公開日2018-12-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution.
Bmc Struct.Biol., 18, 2018
6GDI
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BU of 6gdi by Molmil
Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state
分子名称: Multidrug resistance protein 1A
著者Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A.
登録日2018-04-23
公開日2018-05-23
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution.
Bmc Struct.Biol., 18, 2018
6RQR
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BU of 6rqr by Molmil
Extended NHERF1 PDZ2 domain in complex with the PDZ-binding motif of CFTR
分子名称: Na(+)/H(+) exchange regulatory cofactor NHE-RF1,Cystic fibrosis transmembrane conductance regulator
著者Martin, E.R, Ford, R.C, Robinson, R.C.
登録日2019-05-16
公開日2020-02-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献In vivocrystals reveal critical features of the interaction between cystic fibrosis transmembrane conductance regulator (CFTR) and the PDZ2 domain of Na+/H+exchange cofactor NHERF1.
J.Biol.Chem., 295, 2020
4AV2
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BU of 4av2 by Molmil
Single particle electron microscopy of PilQ dodecameric complexes from Neisseria meningitidis.
分子名称: PILP PROTEIN, TYPE IV PILUS BIOGENESIS AND COMPETENCE PROTEIN PILQ
著者Berry, J.L, Phelan, M.M, Collins, R.F, Adomavicius, T, Tonjum, T, Frye, S.A, Bird, L, Owens, R, Ford, R.C, Lian, L.Y, Derrick, J.P.
登録日2012-05-23
公開日2012-10-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (26 Å)
主引用文献Structure and Assembly of a Trans-Periplasmic Channel for Type Iv Pili in Neisseria Meningitidis.
Plos Pathog., 8, 2012
4CY4
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BU of 4cy4 by Molmil
The Cryo-Electron Microscopy Structure of the CorA channel from Methanocaldococcus jannaschii at 21.6 Angstrom in low magnesium.
分子名称: MAGNESIUM TRANSPORT PROTEIN CORA
著者Cleverley, R.M, Kean, J, Shintre, C.A, Baldock, C, Derrick, J.P, Ford, R.C, Prince, S.M.
登録日2014-04-10
公開日2015-04-22
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (21.6 Å)
主引用文献The Cryo-EM structure of the CorA channel from Methanocaldococcus jannaschii in low magnesium conditions.
Biochim. Biophys. Acta, 1848, 2015
4A82
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BU of 4a82 by Molmil
Fitted model of staphylococcus aureus sav1866 model ABC transporter in the human cystic fibrosis transmembrane conductance regulator volume map EMD-1966.
分子名称: CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
著者Rosenberg, M.F, ORyan, L.P, Hughes, G, Zhao, Z, Aleksandrov, L.A, Riordan, J.R, Ford, R.C.
登録日2011-11-18
公開日2012-01-11
最終更新日2024-05-08
実験手法ELECTRON CRYSTALLOGRAPHY (9 Å)
主引用文献The Cystic Fibrosis Transmembrane Conductance Regulator (Cftr):3D Structure and Localisation of a Channel Gate.
J.Biol.Chem., 286, 2011
4AR0
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BU of 4ar0 by Molmil
N0 domain of Neisseria meningitidis Pilus assembly protein PilQ
分子名称: TYPE IV PILUS BIOGENESIS AND COMPETENCE PROTEIN PILQ
著者Phelan, M.M, Berry, J.L, Derrick, J.P, Lian, L.Y.
登録日2012-04-20
公開日2012-10-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and Assembly of a Trans-Periplasmic Channel for Type Iv Pili in Neisseria Meningitidis.
Plos Pathog., 8, 2012
4AQZ
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BU of 4aqz by Molmil
B2 domain of Neisseria meningitidis Pilus assembly protein PilQ
分子名称: TYPE IV PILUS BIOGENESIS AND COMPETENCE PROTEIN PILQ
著者Phelan, M.M, Berry, J.L, Derrick, J.P, Lian, L.Y.
登録日2012-04-20
公開日2012-10-17
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structure and Assembly of a Trans-Periplasmic Channel for Type Iv Pili in Neisseria Meningitidis.
Plos Pathog., 8, 2012
1PO2
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BU of 1po2 by Molmil
POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R77975, AN INHIBITOR OF VIRAL REPLICATION
分子名称: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
登録日1997-01-08
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1PIV
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BU of 1piv by Molmil
BINDING OF THE ANTIVIRAL DRUG WIN51711 TO THE SABIN STRAIN OF TYPE 3 POLIOVIRUS: STRUCTURAL COMPARISON WITH DRUG BINDING IN RHINOVIRUS 14
分子名称: 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, MYRISTIC ACID, POLIOVIRUS TYPE 3 (SUBUNIT VP1), ...
著者Hiremath, C.N, Grant, R.A, Filman, D.J, Hogle, J.M.
登録日1995-02-02
公開日1995-06-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
Acta Crystallogr.,Sect.D, 51, 1995
1PVC
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BU of 1pvc by Molmil
REFINEMENT OF THE SABIN STRAIN OF TYPE 3 POLIOVIRUS AT 2.4 ANGSTROMS AND THE CRYSTAL STRUCTURES OF ITS VARIANTS AT 2.9 ANGSTROMS RESOLUTION
分子名称: MYRISTIC ACID, POLIOVIRUS TYPE 3, SABIN STRAIN, ...
著者Syed, R, Filman, D.J, Hogle, J.M.
登録日1995-03-30
公開日1995-09-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Refinement of the Sabin Strain of Type 3 Poliovirus at 2.4 Angstroms and the Crystal Structures of its Variants at 2.9 Angstroms Resolution
To be Published
1PO1
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POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R80633, AN INHIBITOR OF VIRAL REPLICATION
分子名称: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
登録日1997-01-08
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1VBD
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BU of 1vbd by Molmil
POLIOVIRUS (TYPE 1, MAHONEY STRAIN) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBE
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BU of 1vbe by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN, MUTANT 242-H2) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBB
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BU of 1vbb by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R80633
分子名称: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBA
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BU of 1vba by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1VBC
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BU of 1vbc by Molmil
POLIOVIRUS (TYPE 3, SABIN STRAIN) (P3/SABIN, P3/LEON/12A(1)B) COMPLEXED WITH R77975
分子名称: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 3
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994

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