8OSP
 
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6HUL
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2X77
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4B6W
 | | Architecture of Trypanosoma brucei Tubulin-Binding cofactor B | | 分子名称: | 1,2-ETHANEDIOL, TUBULIN-SPECIFIC CHAPERONE | | 著者 | Fleming, J.R, Morgan, R.E, Fyfe, P.K, Kelly, S.M, Hunter, W.N. | | 登録日 | 2012-08-15 | | 公開日 | 2012-08-22 | | 最終更新日 | 2013-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The Architecture of Trypanosoma Brucei Tubulin-Binding Cofactor B and Implications for Function.
FEBS J., 280, 2013
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4B6M
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8RYI
 | | Metformin hydrolase from Aminobacter niigataensis MD1 with urea in the active site | | 分子名称: | Agmatinase family protein, Arginase family protein, CALCIUM ION, ... | | 著者 | Fleming, J.R, Lutz, H, Bachmann, A, Mayans, O. | | 登録日 | 2024-02-08 | | 公開日 | 2024-08-28 | | 最終更新日 | 2024-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Metformin hydrolase is a recently evolved nickel-dependent heteromeric ureohydrolase.
Nat Commun, 15, 2024
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7OI1
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7AHS
 | | titin-N2A Ig81-Ig83 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Isoform 5 of Titin, ... | | 著者 | Fleming, J.R, Mayans, O. | | 登録日 | 2020-09-25 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The N2A region of titin has a unique structural configuration.
J.Gen.Physiol., 153, 2021
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6SDB
 | | Chimeric titin Z1Z2 functionalized with a KLER exogenous peptide from decorin | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, PHOSPHATE ION, ... | | 著者 | Fleming, J.R, Hill, C, Mayans, O.M. | | 登録日 | 2019-07-26 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The ZT Biopolymer: A Self-Assembling Protein Scaffold for Stem Cell Applications.
Int J Mol Sci, 20, 2019
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6YGN
 | | Titin kinase and its flanking domains | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Titin | | 著者 | Fleming, J.R, Franke, B, Bogomolovas, J, Mayans, O. | | 登録日 | 2020-03-27 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere.
Embo Rep., 22, 2021
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8BNQ
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8BVO
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8BW6
 | | Titin FnIII-domain I110 (I/A6) from the MIR region | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Mayans, O, Fleming, J.R. | | 登録日 | 2022-12-06 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
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8BXR
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7ESR
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7NIP
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5N2P
 | | Sulfolobus solfataricus Tryptophan Synthase A | | 分子名称: | CHLORIDE ION, TETRAETHYLENE GLYCOL, Tryptophan synthase alpha chain | | 著者 | Fleming, J, Mayans, O. | | 登録日 | 2017-02-08 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.059 Å) | | 主引用文献 | Evolutionary Morphing of Tryptophan Synthase: Functional Mechanisms for the Enzymatic Channeling of Indole.
J.Mol.Biol., 430, 2018
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6HTE
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6FWX
 | | Chimeric titin Z1Z2-Z1Z2 tandem (Z1212) functionalized with a GRGDS exogenous peptide from fibronectin | | 分子名称: | 1,2-ETHANEDIOL, Titin,Titin,Titin | | 著者 | Mayans, O, Fleming, J, Hill, C. | | 登録日 | 2018-03-07 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Self-Assembling Proteins as High-Performance Substrates for Embryonic Stem Cell Self-Renewal.
Adv. Mater. Weinheim, 31, 2019
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5JOE
 | | Crystal structure of I81 from titin | | 分子名称: | 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Titin | | 著者 | Fleming, J, Zhou, T, Bogomolovas, J, Labeit, S, Mayans, O. | | 登録日 | 2016-05-02 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | CARP interacts with titin at a unique helical N2A sequence and at the domain Ig81 to form a structured complex.
Febs Lett., 590, 2016
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5JDE
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5JDD
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5JDJ
 | | Crystal structure of domain I10 from titin in space group P212121 | | 分子名称: | CALCIUM ION, Titin | | 著者 | Williams, R, Bogomolovas, J, Labiet, S, Mayans, O. | | 登録日 | 2016-04-16 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.738 Å) | | 主引用文献 | Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I.
Open Biology, 6, 2016
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