8RYI

Metformin hydrolase from Aminobacter niigataensis MD1 with urea in the active site

Summary for 8RYI

Entry DOI	10.2210/pdb8ryi/pdb
Descriptor	Arginase family protein, Agmatinase family protein, dicarbonimidic diamide, ... (7 entities in total)
Functional Keywords	metformin hydrolase, ureohydrolase, nickel-dependent, metal binding protein
Biological source	Aminobacter niigataensis More
Total number of polymer chains	6
Total formula weight	236979.49
Authors	Fleming, J.R.,Lutz, H.,Bachmann, A.,Mayans, O. (deposition date: 2024-02-08, release date: 2024-08-28, Last modification date: 2024-10-02)
Primary citation	Sinn, M.,Riede, L.,Fleming, J.R.,Funck, D.,Lutz, H.,Bachmann, A.,Mayans, O.,Hartig, J.S. Metformin hydrolase is a recently evolved nickel-dependent heteromeric ureohydrolase. Nat Commun, 15:8045-8045, 2024 Cited by PubMed: 39271653 DOI: 10.1038/s41467-024-51752-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.06 Å)

Structure validation