6NWD
 
 | | X-ray Crystallographic structure of Gloeobacter rhodopsin | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, DECANE, DODECANE, ... | | 著者 | Ernst, O.P, Morizumi, T, Ou, W.L. | | 登録日 | 2019-02-06 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray Crystallographic Structure and Oligomerization of Gloeobacter Rhodopsin.
Sci Rep, 9, 2019
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8GI8
 | | Kalium channelrhodopsin 1 from Hyphochytrium catenoides (HcKCR1) embedded in peptidisc | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHOLESTEROL, Kalium Channelrhodopsin 1, ... | | 著者 | Morizumi, T, Kim, K, Li, H, Spudich, J.L, Ernst, O.P. | | 登録日 | 2023-03-13 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structures of channelrhodopsin paralogs in peptidiscs explain their contrasting K + and Na + selectivities.
Nat Commun, 14, 2023
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8GI9
 | | Cation channelrhodopsin from Hyphochytrium catenoides (HcCCR) embedded in peptidisc | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CHOLESTEROL, Cation Channelrhodopsin, ... | | 著者 | Morizumi, T, Kim, K, Li, H, Spudich, J.L, Ernst, O.P. | | 登録日 | 2023-03-13 | | 公開日 | 2023-07-26 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Structures of channelrhodopsin paralogs in peptidiscs explain their contrasting K + and Na + selectivities.
Nat Commun, 14, 2023
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5JGV
 | | Spin-Labeled T4 Lysozyme Construct A73V1 | | 分子名称: | CHLORIDE ION, Endolysin, HEXANE-1,6-DIOL, ... | | 著者 | Balo, A.R, Feyrer, H, Ernst, O.P. | | 登録日 | 2016-04-20 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.732 Å) | | 主引用文献 | Toward Precise Interpretation of DEER-Based Distance Distributions: Insights from Structural Characterization of V1 Spin-Labeled Side Chains.
Biochemistry, 55, 2016
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5WJK
 | | 2.0-Angstrom In situ Mylar structure of sperm whale myoglobin (SWMb) at 293 K | | 分子名称: | CHLORIDE ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Broecker, J, Ou, W.-L, Ernst, O.P. | | 登録日 | 2017-07-23 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.
Nat Protoc, 13, 2018
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5WKT
 | | 3.2-Angstrom In situ Mylar structure of bovine opsin at 100 K | | 分子名称: | Rhodopsin, SULFATE ION, Transducin Galpha peptide, ... | | 著者 | Broecker, J, Morizumi, T, Ou, W.-L, Ernst, O.P. | | 登録日 | 2017-07-25 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions.
Nat Protoc, 13, 2018
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4J4Q
 | | Crystal structure of active conformation of GPCR opsin stabilized by octylglucoside | | 分子名称: | ACETATE ION, Guanine nucleotide-binding protein G(t) subunit alpha-1, PALMITIC ACID, ... | | 著者 | Park, J.H, Morizumi, T, Li, Y, Hong, J.E, Pai, E.F, Hofmann, K.P, Choe, H.W, Ernst, O.P. | | 登録日 | 2013-02-07 | | 公開日 | 2013-10-30 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Opsin, a structural model for olfactory receptors?
Angew.Chem.Int.Ed.Engl., 52, 2013
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6XL3
 | | Mastigocladopsis repens rhodopsin chloride pump | | 分子名称: | CHLORIDE ION, DECANE, Mastigocladopsis repens rhodopsin chloride pump, ... | | 著者 | Besaw, J.E, Ernst, O.P, Ou, W, Morizumi, T. | | 登録日 | 2020-06-28 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | The crystal structures of a chloride-pumping microbial rhodopsin and its proton-pumping mutant illuminate proton transfer determinants.
J.Biol.Chem., 295, 2020
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7U55
 | | Crystal structure of Thermoplasmatales archaeon heliorhodopsin at pH 4.5 | | 分子名称: | CHLORIDE ION, DODECANE, Heliorhodopsin, ... | | 著者 | Besaw, J.E, De Guzman, P, Miller, R.J.D, Ernst, O.P. | | 登録日 | 2022-03-01 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Low pH structure of heliorhodopsin reveals chloride binding site and intramolecular signaling pathway.
Sci Rep, 12, 2022
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6V51
 | | Spin-labeled T4 Lysozyme (9/131FnbY)-(4-Amino-TEMPO) | | 分子名称: | 4-amino-2,2,6,6-tetramethylpiperidin-1-ol, Endolysin | | 著者 | Liu, J, Morizumi, T, Ou, W.L, Wang, L, Ernst, O.P. | | 登録日 | 2019-12-02 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Genetically Encoded Quinone Methides Enabling Rapid, Site-Specific, and Photocontrolled Protein Modification with Amine Reagents.
J.Am.Chem.Soc., 142, 2020
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6WP8
 | | Proton-pumping mutant of Mastigocladopsis repens rhodopsin chloride pump | | 分子名称: | Proton-pumping rhodopsin chloride pump, RETINAL, octyl beta-D-glucopyranoside | | 著者 | Besaw, J.E, Ernst, O.P, Ou, W, Morizumi, T. | | 登録日 | 2020-04-26 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structures of a chloride-pumping microbial rhodopsin and its proton-pumping mutant illuminate proton transfer determinants.
J.Biol.Chem., 295, 2020
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8EL2
 | | SARS-CoV-2 RBD bound to neutralizing antibody Fab ICO-hu23 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab ICO-hu23 Heavy Chain, Fab ICO-hu23 Light Chain, ... | | 著者 | Besaw, J.E, Kuo, A, Morizumi, T, Ernst, O.P. | | 登録日 | 2022-09-22 | | 公開日 | 2023-07-19 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates.
Plos Pathog., 19, 2023
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8ELJ
 | | SARS-CoV-2 spike glycoprotein in complex with the ICO-hu23 neutralizing antibody Fab fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ICO-hu23 antibody Fab heavy chain, ... | | 著者 | Yee, A.W, Morizumi, T, Kim, K, Kuo, A, Ernst, O.P. | | 登録日 | 2022-09-24 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates.
Plos Pathog., 19, 2023
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3CAP
 | | Crystal Structure of Native Opsin: the G Protein-Coupled Receptor Rhodopsin in its Ligand-free State | | 分子名称: | 2-O-octyl-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... | | 著者 | Park, J.H, Scheerer, P, Hofmann, K.P, Choe, H.-W, Ernst, O.P. | | 登録日 | 2008-02-20 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the ligand-free G-protein-coupled receptor opsin
Nature, 454, 2008
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3PQR
 | | Crystal structure of Metarhodopsin II in complex with a C-terminal peptide derived from the Galpha subunit of transducin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Guanine nucleotide-binding protein G(t) subunit alpha-1, ... | | 著者 | Choe, H.-W, Kim, Y.J, Park, J.H, Morizumi, T, Pai, E.F, Krauss, N, Hofmann, K.P, Scheerer, P, Ernst, O.P. | | 登録日 | 2010-11-26 | | 公開日 | 2011-03-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Crystal structure of metarhodopsin II.
Nature, 471, 2011
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3PXO
 | | Crystal structure of Metarhodopsin II | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, RETINAL, ... | | 著者 | Choe, H.-W, Kim, Y.J, Park, J.H, Morizumi, T, Pai, E.F, Krauss, N, Hofmann, K.P, Scheerer, P, Ernst, O.P. | | 登録日 | 2010-12-10 | | 公開日 | 2011-03-09 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of metarhodopsin II.
Nature, 471, 2011
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3DQB
 | | Crystal structure of the active G-protein-coupled receptor opsin in complex with a C-terminal peptide derived from the Galpha subunit of transducin | | 分子名称: | 11meric peptide form Guanine nucleotide-binding protein G(t) subunit alpha-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, ... | | 著者 | Scheerer, P, Park, J.H, Hildebrand, P.W, Kim, Y.J, Krauss, N, Choe, H.-W, Hofmann, K.P, Ernst, O.P. | | 登録日 | 2008-07-09 | | 公開日 | 2008-09-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of opsin in its G-protein-interacting conformation
Nature, 455, 2008
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6BK9
 | | Crystal Structure of Squid Arrestin | | 分子名称: | CHLORIDE ION, Visual arrestin | | 著者 | Eger, B.T, Bandyopadhyay, A, Yedidi, R.S, Ernst, O.P. | | 登録日 | 2017-11-08 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.00005579 Å) | | 主引用文献 | A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin.
J. Mol. Biol., 430, 2018
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7F1W
 | | X-ray crystal structure of visual arrestin complexed with inositol hexaphosphate | | 分子名称: | INOSITOL HEXAKISPHOSPHATE, S-arrestin | | 著者 | Kang, M, Jang, K, Eger, B.T, Ernst, O.P, Choe, H.W, Kim, Y.J. | | 登録日 | 2021-06-10 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.097 Å) | | 主引用文献 | Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
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7F1X
 | | X-ray crystal structure of visual arrestin complexed with inositol 1,4,5-triphosphate | | 分子名称: | 1,2-ETHANEDIOL, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, PENTANEDIAL, ... | | 著者 | Jang, K, Kang, M, Eger, B.T, Choe, H.W, Ernst, O.P, Kim, Y.J. | | 登録日 | 2021-06-10 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural evidence for visual arrestin priming via complexation of phosphoinositols.
Structure, 30, 2022
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5ITE
 | | 2.2-Angstrom in meso crystal structure of Haloquadratum Walsbyi Bacteriorhodopsin (HwBR) from Octylglucoside (OG) Detergent Micelles | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Bacteriorhodopsin-I, ... | | 著者 | Broecker, J, Eger, B.T, Ernst, O.P. | | 登録日 | 2016-03-16 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.182 Å) | | 主引用文献 | Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs.
Structure, 25, 2017
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5ITC
 | | 2.2-Angstrom in meso crystal structure of Haloquadratum Walsbyi Bacteriorhodopsin (HwBR) from Styrene Maleic Acid (SMA) Polymer Nanodiscs | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Bacteriorhodopsin-I, ... | | 著者 | Broecker, J, Eger, B.T, Ernst, O.P. | | 登録日 | 2016-03-16 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs.
Structure, 25, 2017
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4ZWJ
 | | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser | | 分子名称: | Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin | | 著者 | Kang, Y, Zhou, X.E, Gao, X, He, Y, Liu, W, Ishchenko, A, Barty, A, White, T.A, Yefanov, O, Han, G.W, Xu, Q, de Waal, P.W, Ke, J, Tan, M.H.E, Zhang, C, Moeller, A, West, G.M, Pascal, B, Eps, N.V, Caro, L.N, Vishnivetskiy, S.A, Lee, R.J, Suino-Powell, K.M, Gu, X, Pal, K, Ma, J, Zhi, X, Boutet, S, Williams, G.J, Messerschmidt, M, Gati, C, Zatsepin, N.A, Wang, D, James, D, Basu, S, Roy-Chowdhury, S, Conrad, C, Coe, J, Liu, H, Lisova, S, Kupitz, C, Grotjohann, I, Fromme, R, Jiang, Y, Tan, M, Yang, H, Li, J, Wang, M, Zheng, Z, Li, D, Howe, N, Zhao, Y, Standfuss, J, Diederichs, K, Dong, Y, Potter, C.S, Carragher, B, Caffrey, M, Jiang, H, Chapman, H.N, Spence, J.C.H, Fromme, P, Weierstall, U, Ernst, O.P, Katritch, V, Gurevich, V.V, Griffin, P.R, Hubbell, W.L, Stevens, R.C, Cherezov, V, Melcher, K, Xu, H.E, GPCR Network (GPCR) | | 登録日 | 2015-05-19 | | 公開日 | 2015-07-29 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.302 Å) | | 主引用文献 | Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Nature, 523, 2015
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6PEL
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6PGS
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