3DQB

Crystal structure of the active G-protein-coupled receptor opsin in complex with a C-terminal peptide derived from the Galpha subunit of transducin

Summary for 3DQB

DescriptorRhodopsin, 11meric peptide form Guanine nucleotide-binding protein G(t) subunit alpha-1, N-ACETYL-D-GLUCOSAMINE, ... (8 entities in total)
Functional Keywordsprotein, retinal protein, photoreceptor, ligand-free state, chromophore, g-protein coupled receptor, glycoprotein, lipoprotein, palmitate, phosphoprotein, photoreceptor protein, sensory transduction, transducer, transmembrane, vision, signaling protein, g-protein, transducin, galpha subunit, membrane, receptor, gtp-binding, myristate, nucleotide-binding, g-protein-coupled receptor, rhodopsin, opsin
Biological sourceBos taurus (Bovine)
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Cellular locationMembrane; Multi-pass membrane protein P02699
Total number of polymer chains2
Total molecular weight42932.06
Authors
Scheerer, P.,Park, J.H.,Hildebrand, P.W.,Kim, Y.J.,Krauss, N.,Choe, H.-W.,Hofmann, K.P.,Ernst, O.P. (deposition date: 2008-07-09, release date: 2008-09-23, Last modification date: 2014-02-05)
Primary citation
Scheerer, P.,Park, J.H.,Hildebrand, P.W.,Kim, Y.J.,Krauss, N.,Choe, H.-W.,Hofmann, K.P.,Ernst, O.P.
Crystal structure of opsin in its G-protein-interacting conformation
Nature, 455:497-502, 2008
PubMed: 18818650 (PDB entries with the same primary citation)
DOI: 10.1038/nature07330
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.2 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.249371.2%4.5%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution