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1KY9
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BU of 1ky9 by Molmil
Crystal Structure of DegP (HtrA)
分子名称: PROTEASE DO
著者Krojer, T, Garrido-Franco, M, Huber, R, Ehrmann, M, Clausen, T.
登録日2002-02-04
公開日2002-04-03
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine.
Nature, 416, 2002
3CS0
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BU of 3cs0 by Molmil
Crystal structure of DegP24
分子名称: Periplasmic serine endoprotease DegP, pentapeptide
著者Krojer, T, Sawa, J, Schaefer, E, Saibil, H.R, Ehrmann, M, Clausen, T.
登録日2008-04-08
公開日2008-05-27
最終更新日2019-11-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
6Z0E
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BU of 6z0e by Molmil
HtrA1 inactive protease domain S328A with CARASIL mutation R274Q
分子名称: CALCIUM ION, Serine protease HTRA1
著者Vetter, I.R, Stege, P, Ingendahl, L, Ehrmann, M.
登録日2020-05-08
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Repair strategies addressing pathogenic protein conformations
To Be Published
6Z0X
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BU of 6z0x by Molmil
HtrA1 inactive protease domain S328A with CARASIL mutations D174R R274Q
分子名称: SULFATE ION, Serine protease HTRA1
著者Vetter, I.R, Stege, P, Ingendahl, L, Ehrmann, M.
登録日2020-05-11
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Repair strategies addressing pathogenic protein conformations
To Be Published
6Z0Y
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BU of 6z0y by Molmil
HtrA1 inactive protease domain S328A with CARASIL mutations D174R R274Q
分子名称: SULFATE ION, Serine protease HTRA1
著者Vetter, I.R, Stege, P, Ingendahl, L, Ehrmann, M.
登録日2020-05-11
公開日2021-05-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Repair strategies addressing pathogenic protein conformations
To Be Published
3NWU
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BU of 3nwu by Molmil
Substrate induced remodeling of the active site regulates HtrA1 activity
分子名称: SULFATE ION, Serine protease HTRA1
著者Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M.
登録日2010-07-11
公開日2011-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
3NUM
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BU of 3num by Molmil
Substrate induced remodeling of the active site regulates HtrA1 activity
分子名称: Serine protease HTRA1
著者Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M.
登録日2010-07-07
公開日2011-02-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
3NZI
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BU of 3nzi by Molmil
Substrate induced remodeling of the active site regulates HtrA1 activity
分子名称: Citrate synthase, Serine protease HTRA1
著者Truebestein, L, Tennstaedt, A, Hauske, P, Krojer, T, Kaiser, M, Clausen, T, Ehrmann, M.
登録日2010-07-16
公開日2011-02-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat.Struct.Mol.Biol., 18, 2011
4A8D
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BU of 4a8d by Molmil
DegP dodecamer with bound OMP
分子名称: OUTER MEMBRANE PROTEIN C, PERIPLASMIC SERINE ENDOPROTEASE DEGP
著者Malet, H, Krojer, T, Sawa, J, Schafer, E, Saibil, H.R, Ehrmann, M, Clausen, T.
登録日2011-11-20
公開日2012-01-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (28 Å)
主引用文献Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
1SOZ
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BU of 1soz by Molmil
Crystal Structure of DegS protease in complex with an activating peptide
分子名称: Protease degS, activating peptide
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-16
公開日2004-06-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
1SOT
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BU of 1sot by Molmil
Crystal Structure of the DegS stress sensor
分子名称: Protease degS
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-15
公開日2004-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease
Cell(Cambridge,Mass.), 117, 2004
3STI
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BU of 3sti by Molmil
Crystal structure of the protease domain of DegQ from Escherichia coli
分子名称: Protease degQ
著者Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T.
登録日2011-07-11
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
3STJ
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BU of 3stj by Molmil
Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli
分子名称: Protease degQ, peptide (UNK)
著者Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T.
登録日2011-07-11
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
1VCW
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BU of 1vcw by Molmil
Crystal structure of DegS after backsoaking the activating peptide
分子名称: Protease degS
著者Wilken, C, Kitzing, K, Kurzbauer, R, Ehrmann, M, Clausen, T.
登録日2004-03-16
公開日2004-06-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.
Cell(Cambridge,Mass.), 117, 2004
4A8A
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BU of 4a8a by Molmil
Asymmetric cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozyme
分子名称: LYSOZYME C, PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
著者Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R.
登録日2011-11-20
公開日2011-12-28
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (14.2 Å)
主引用文献Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A9G
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BU of 4a9g by Molmil
Symmetrized cryo-EM reconstruction of E. coli DegQ 24-mer in complex with beta-casein
分子名称: PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
著者Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R.
登録日2011-11-26
公開日2012-01-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A8B
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BU of 4a8b by Molmil
Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with lysozymes
分子名称: LYSOZYME C, PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
著者Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R.
登録日2011-11-20
公開日2012-01-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
4A8C
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BU of 4a8c by Molmil
Symmetrized cryo-EM reconstruction of E. coli DegQ 12-mer in complex with a binding peptide
分子名称: PERIPLASMIC PH-DEPENDENT SERINE ENDOPROTEASE DEGQ
著者Malet, H, Canellas, F, Sawa, J, Yan, J, Thalassinos, K, Ehrmann, M, Clausen, T, Saibil, H.R.
登録日2011-11-20
公開日2012-01-11
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Newly Folded Substrates Inside the Molecular Cage of the Htra Chaperone Degq
Nat.Struct.Mol.Biol., 19, 2012
2R3Y
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BU of 2r3y by Molmil
Crystal structure of the DegS protease in complex with the YWF activating peptide
分子名称: Protease degS, Synthetic peptide YWF
著者Clausen, T, Hasselblatt, H.
登録日2007-08-30
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
6EW9
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BU of 6ew9 by Molmil
CRYSTAL STRUCTURE OF DEGS STRESS SENSOR PROTEASE IN COMPLEX WITH ACTIVATING DNRLGLVYQF PEPTIDE
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNRLGLVYQF PEPTIDE, ...
著者Vetter, I.R, Porfetye, A.T, Stege, P.
登録日2017-11-03
公開日2018-04-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Identification of Noncatalytic Lysine Residues from Allosteric Circuits via Covalent Probes.
ACS Chem. Biol., 13, 2018
2R3U
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BU of 2r3u by Molmil
Crystal structure of the PDZ deletion mutant of DegS
分子名称: Protease degS
著者Clausen, T, Kurzbauer, R.
登録日2007-08-30
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev., 21, 2007
2ZLE
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BU of 2zle by Molmil
Cryo-EM structure of DegP12/OMP
分子名称: Outer membrane protein C, Protease do
著者Schaefer, E, Saibil, H.R.
登録日2008-04-09
公開日2008-06-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (28 Å)
主引用文献Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
4RQZ
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BU of 4rqz by Molmil
re-refinement of 1soz, Crystal Structure of DegS protease in complex with an activating peptide
分子名称: Protease degS, activating peptide
著者Sauer, R.T, Grant, R.A.
登録日2014-11-05
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015
4RR0
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BU of 4rr0 by Molmil
re-refined 1vcw, CRYSTAL STRUCTURE OF DEGS AFTER BACKSOAKING THE ACTIVATING PEPTIDE
分子名称: Protease degS
著者Sauer, R.T, Grant, R.A.
登録日2014-11-05
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.054 Å)
主引用文献A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015
4RR1
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BU of 4rr1 by Molmil
re-refinement of entry 1sot, Crystal Structure of the DegS stress sensor
分子名称: NICKEL (II) ION, PHOSPHATE ION, Protease degS
著者Sauer, R.T, Grant, R.A.
登録日2014-11-05
公開日2015-03-11
最終更新日2015-03-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases.
Structure, 23, 2015

 

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