5V6P
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![BU of 5v6p by Molmil](/molmil-images/mine/5v6p) | CryoEM structure of the ERAD-associated E3 ubiquitin-protein ligase HRD1 | 分子名称: | ERAD-associated E3 ubiquitin-protein ligase HRD1 | 著者 | Schoebel, S, Mi, W, Stein, A, Rapoport, T.A, Liao, M. | 登録日 | 2017-03-17 | 公開日 | 2017-08-16 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3. Nature, 548, 2017
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3JZA
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![BU of 3jza by Molmil](/molmil-images/mine/3jza) | Crystal structure of human Rab1b in complex with the GEF domain of DrrA/SidM from Legionella pneumophila | 分子名称: | PHOSPHATE ION, Ras-related protein Rab-1B, Uncharacterized protein DrrA | 著者 | Schoebel, S, Oesterlin, L.K, Blankenfeldt, W, Goody, R.S, Itzen, A. | 登録日 | 2009-09-23 | 公開日 | 2010-01-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity. Mol.Cell, 36, 2009
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3JZ9
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![BU of 3jz9 by Molmil](/molmil-images/mine/3jz9) | Crystal structure of the GEF domain of DrrA/SidM from Legionella pneumophila | 分子名称: | Uncharacterized protein DrrA | 著者 | Schoebel, S, Oesterlin, L.K, Blankenfeldt, W, Goody, R.S, Itzen, A. | 登録日 | 2009-09-23 | 公開日 | 2010-01-19 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity. Mol.Cell, 36, 2009
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3N6O
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![BU of 3n6o by Molmil](/molmil-images/mine/3n6o) | Crystal structure of the GEF and P4M domain of DrrA/SidM from Legionella pneumophila | 分子名称: | SULFATE ION, guanine nucleotide exchange factor | 著者 | Schoebel, S, Blankenfeldt, W, Goody, R.S, Itzen, A. | 登録日 | 2010-05-26 | 公開日 | 2010-07-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA. Embo Rep., 11, 2010
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3TNF
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![BU of 3tnf by Molmil](/molmil-images/mine/3tnf) | LidA from Legionella in complex with active Rab8a | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, LidA, MAGNESIUM ION, ... | 著者 | Schoebel, S, Cichy, A.L, Goody, R.S, Itzen, A. | 登録日 | 2011-09-01 | 公開日 | 2011-11-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Protein LidA from Legionella is a Rab GTPase supereffector. Proc.Natl.Acad.Sci.USA, 108, 2011
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5V7V
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![BU of 5v7v by Molmil](/molmil-images/mine/5v7v) | Cryo-EM structure of ERAD-associated E3 ubiquitin-protein ligase component HRD3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ERAD-associated E3 ubiquitin-protein ligase component HRD3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Mi, W, Schoebel, S, Stein, A, Rapoport, T.A, Liao, M. | 登録日 | 2017-03-20 | 公開日 | 2017-08-16 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3. Nature, 548, 2017
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6QIM
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![BU of 6qim by Molmil](/molmil-images/mine/6qim) | Structure of AtPIP2;4 | 分子名称: | Probable aquaporin PIP2-4 | 著者 | Schoebel, S, Wang, H. | 登録日 | 2019-01-21 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Characterization of aquaporin-driven hydrogen peroxide transport. Biochim Biophys Acta Biomembr, 1862, 2020
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157D
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![BU of 157d by Molmil](/molmil-images/mine/157d) | CRYSTAL AND MOLECULAR STRUCTURE OF R(CGCGAAUUAGCG): AN RNA DUPLEX CONTAINING TWO G(ANTI).A(ANTI) BASE-PAIRS | 分子名称: | RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*AP*GP*CP*G)-3') | 著者 | Leonard, G.A, McAuley-Hecht, K.E, Ebel, S, Lough, D.M, Brown, T, Hunter, W.N. | 登録日 | 1994-02-01 | 公開日 | 1994-05-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal and molecular structure of r(CGCGAAUUAGCG): an RNA duplex containing two G(anti).A(anti) base pairs. Structure, 2, 1994
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2BM2
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![BU of 2bm2 by Molmil](/molmil-images/mine/2bm2) | human beta-II tryptase in complex with 4-(3-Aminomethyl-phenyl)- piperidin-1-yl-(5-phenethyl- pyridin-3-yl)-methanone | 分子名称: | 1-[3-(1-{[5-(2-PHENYLETHYL)PYRIDIN-3-YL]CARBONYL}PIPERIDIN-4-YL)PHENYL]METHANAMINE, HUMAN BETA2 TRYPTASE | 著者 | Maignan, S, Guilloteau, J.-P, Dupuy, A, Levell, J, Astles, P, Eastwood, P, Cairns, J, Houille, O, Aldous, S, Merriman, G, Whiteley, B, Pribish, J, Czekaj, M, Liang, G, Davidson, J, Harrison, T, Morley, A, Watson, S, Fenton, G, Mccarthy, C, Romano, J, Mathew, R, Engers, D, Gardyan, M, Sides, K, Kwong, J, Tsay, J, Rebello, S, Shen, L, Wang, J, Luo, Y, Giardino, O, Lim, H.-K, Smith, K, Pauls, H. | 登録日 | 2005-03-09 | 公開日 | 2005-03-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure Based Design of 4-(3-Aminomethylphenyl) Piperidinyl-1-Amides: Novel, Potent, Selective, and Orally Bioavailable Inhibitors of Bii Tryptase Bioorg.Med.Chem., 13, 2005
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3QBT
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![BU of 3qbt by Molmil](/molmil-images/mine/3qbt) | Crystal structure of OCRL1 540-678 in complex with Rab8a:GppNHp | 分子名称: | Inositol polyphosphate 5-phosphatase OCRL-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Hou, X, Hagemann, N, Schoebel, S, Blankenfeldt, W, Goody, R.S, Erdmann, K.S, Itzen, A. | 登録日 | 2011-01-14 | 公開日 | 2011-03-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1. Embo J., 30, 2011
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6EV2
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![BU of 6ev2 by Molmil](/molmil-images/mine/6ev2) | Crystal structure of antibody against schizophyllan in complex with laminarihexaose | 分子名称: | Heavy chain, Light chain, beta-D-glucopyranose, ... | 著者 | Sung, K.H, Josewski, J, Duebel, S, Blankenfeldt, W, Rau, U. | 登録日 | 2017-11-01 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | 主引用文献 | Structural insights into antigen recognition of an anti-beta-(1,6)-beta-(1,3)-D-glucan antibody. Sci Rep, 8, 2018
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4A6L
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![BU of 4a6l by Molmil](/molmil-images/mine/4a6l) | beta-tryptase inhibitor | 分子名称: | 1-{3-[1-({5-[(2-fluorophenyl)ethynyl]furan-2-yl}carbonyl)piperidin-4-yl]phenyl}methanamine, TRYPTASE ALPHA/BETA-1 | 著者 | Mathieu, M, Maignan, S. | 登録日 | 2011-11-04 | 公開日 | 2012-01-25 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure-Based Library Design and the Discovery of a Potent and Selective Mast Cell Beta-Tryptase Inhibitor as an Oral Therapeutic Agent. Bioorg.Med.Chem.Lett., 22, 2012
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4OOJ
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![BU of 4ooj by Molmil](/molmil-images/mine/4ooj) | Crystal structure of the N-terminal domain of the Legionella pneumophila protein SidC at 2.4A resolution | 分子名称: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, SidC, ... | 著者 | Gazdag, E.M, Shoebel, S, Shkumatov, A.V, Goody, R.S, Itzen, A. | 登録日 | 2014-02-03 | 公開日 | 2014-02-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The structure of the N-terminal domain of the Legionella protein SidC J.Struct.Biol., 186, 2014
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8AG2
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![BU of 8ag2 by Molmil](/molmil-images/mine/8ag2) | Crystal structure of the BPTF bromodomain in complex with BI-7190 | 分子名称: | 5-[3-methoxy-4-[1-(4-methylpiperazin-1-yl)cyclopropyl]phenyl]-1,3,4-trimethyl-pyridin-2-one, Nucleosome-remodeling factor subunit BPTF | 著者 | Bader, G, Boettcher, J, Wolkerstorfer, B. | 登録日 | 2022-07-19 | 公開日 | 2022-08-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.025 Å) | 主引用文献 | Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments. Chemmedchem, 18, 2023
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8AHC
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![BU of 8ahc by Molmil](/molmil-images/mine/8ahc) | Crystal structure of the BRD9 bromodomain with BI-7189 | 分子名称: | Bromodomain-containing protein 9, [2,6-dimethoxy-4-(1,2,5-trimethyl-6-oxidanylidene-pyridin-3-yl)phenyl]methyl-dimethyl-azanium | 著者 | Bader, G, Boettcher, J, Weiss-Puxbaum, A. | 登録日 | 2022-07-21 | 公開日 | 2023-06-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.504 Å) | 主引用文献 | Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments. Chemmedchem, 18, 2023
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