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6DWX
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BU of 6dwx by Molmil
Crystal structure of SeMet phased viral OTU domain protease from Qalyub virus
分子名称: RNA-dependent RNA polymerase
著者Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D.
登録日2018-06-28
公開日2018-12-19
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (2.395 Å)
主引用文献Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
8CT6
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BU of 8ct6 by Molmil
1F8 mAb in complex with the computationally optimized broadly reactive H1 influenza hemagglutinin P1
分子名称: 1F8 heavy chain, 1F8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dzimianski, J.V, DuBois, R.M.
登録日2022-05-13
公開日2023-04-19
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine.
Commun Biol, 6, 2023
7JMS
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BU of 7jms by Molmil
Structure of the Hazara virus OTU bound to ubiquitin
分子名称: CALCIUM ION, GLYCEROL, Polyubiquitin-B, ...
著者Dzimianski, J.V, Pegan, S.D.
登録日2020-08-02
公開日2020-10-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Flipping the substrate preference of Hazara virus ovarian tumour domain protease through structure-based mutagenesis.
Acta Crystallogr D Struct Biol, 76, 2020
7UYI
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BU of 7uyi by Molmil
Crystal structure of the computationally optimized broadly reactive H1 influenza hemagglutinin P1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COBRA P1 HA, ...
著者Dzimianski, J.V, DuBois, R.M.
登録日2022-05-06
公開日2023-04-19
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into the broad protection against H1 influenza viruses by a computationally optimized hemagglutinin vaccine.
Commun Biol, 6, 2023
6OAR
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BU of 6oar by Molmil
Structure of the Kupe virus OTU bound to the C-terminal domain of sheep ISG15
分子名称: Interferon stimulated gene 17, RNA-dependent RNA polymerase, prop-2-en-1-amine
著者Dzimianski, J.V, Williams, I.L, Pegan, S.D.
登録日2019-03-18
公開日2020-01-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.063 Å)
主引用文献Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases.
Plos One, 14, 2019
6OAT
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BU of 6oat by Molmil
Structure of the Ganjam virus OTU bound to sheep ISG15
分子名称: Interferon stimulated gene 17, RNA-dependent RNA polymerase, prop-2-en-1-amine
著者Dzimianski, J.V, Williams, I.L, Pegan, S.D.
登録日2019-03-18
公開日2020-01-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases.
Plos One, 14, 2019
6DX1
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BU of 6dx1 by Molmil
Crystal structure of the viral OTU domain protease from Qalyub virus
分子名称: RNA-dependent RNA polymerase
著者Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D.
登録日2018-06-28
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.652 Å)
主引用文献Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
6DX3
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BU of 6dx3 by Molmil
Crystal structure of the viral OTU domain protease from Taggert virus
分子名称: MAGNESIUM ION, RNA-dependent RNA polymerase
著者Dzimianski, J.V, Beldon, B.S, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D.
登録日2018-06-28
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.052 Å)
主引用文献Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
8SJ9
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BU of 8sj9 by Molmil
Crystal structure of the H1 hemagglutinin COBRA X6
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dzimianski, J.V, DuBois, R.M.
登録日2023-04-17
公開日2024-05-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6.
Structure, 2024
5TL6
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BU of 5tl6 by Molmil
Crystal structure of SARS-CoV papain-like protease in complex with the C-terminal domain of human ISG15
分子名称: Replicase polyprotein 1ab, SULFATE ION, Ubiquitin-like protein ISG15, ...
著者Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D.
登録日2016-10-10
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.618 Å)
主引用文献Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.
J. Mol. Biol., 429, 2017
6DX2
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BU of 6dx2 by Molmil
Crystal structure of the viral OTU domain protease from Dera Ghazi Khan virus
分子名称: RNA-dependent RNA polymerase
著者Beldon, B.S, Dzimianski, J.V, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D.
登録日2018-06-28
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.614 Å)
主引用文献Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
6DX5
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BU of 6dx5 by Molmil
Crystal structure of the viral OTU domain protease from Farallon virus
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, RNA-dependent RNA polymerase
著者Beldon, B.S, Dzimianski, J.V, Daczkowski, C.M, Goodwin, O.Y, Pegan, S.D.
登録日2018-06-28
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.224 Å)
主引用文献Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity.
PLoS Pathog., 15, 2019
7MC9
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BU of 7mc9 by Molmil
X-RAY STRUCTURE OF PEDV PAPAIN-LIKE PROTEASE 2 bound to UB-PA
分子名称: 3C-like proteinase, Ubiquitin, ZINC ION, ...
著者Durie, I.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D.
登録日2021-04-01
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.099 Å)
主引用文献Structural insights into the interaction of papain-like protease 2 from the alphacoronavirus porcine epidemic diarrhea virus and ubiquitin
Acta Cryst. D, 77, 2021
6MDH
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BU of 6mdh by Molmil
X-ray crystal structure of ISG15 from Myotis davidii
分子名称: Ubiquitin-like protein ISG15
著者Goodwin, O.Y, Langley, C.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D.
登録日2018-09-04
公開日2018-12-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Structure of interferon-stimulated gene product 15 (ISG15) from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement.
Acta Crystallogr D Struct Biol, 75, 2019
5JZE
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BU of 5jze by Molmil
Erve virus viral OTU domain protease in complex with mouse ISG15
分子名称: CITRATE ANION, RNA-dependent RNA polymerase, Ubiquitin-like protein ISG15, ...
著者Deaton, M.K, Dzimianski, J.V, Pegan, S.D.
登録日2016-05-16
公開日2016-10-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Biochemical and Structural Insights into the Preference of Nairoviral DeISGylases for Interferon-Stimulated Gene Product 15 Originating from Certain Species.
J.Virol., 90, 2016
5W8T
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BU of 5w8t by Molmil
Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ORF1ab, Ubiquitin-like protein ISG15, ...
著者Daczkowski, C.M, Goodwin, O.Y, Dzimianski, J.V, Farhat, J.J, Pegan, S.D.
登録日2017-06-22
公開日2017-09-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.758 Å)
主引用文献Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.
J. Virol., 91, 2017
5TL7
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BU of 5tl7 by Molmil
Crystal structure of SARS-CoV papain-like protease in complex with C-terminal domain mouse ISG15
分子名称: Replicase polyprotein 1ab, Ubiquitin-like protein ISG15, ZINC ION
著者Daczkowski, C.D, Dzimianski, J.V, Pegan, S.D.
登録日2016-10-10
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.
J. Mol. Biol., 429, 2017
5TLA
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BU of 5tla by Molmil
Crystal structure of mouse ISG15
分子名称: Ubiquitin-like protein ISG15
著者Goodwin, O.Y, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D.
登録日2016-10-10
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.244 Å)
主引用文献Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.
J. Mol. Biol., 429, 2017
8GHK
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BU of 8ghk by Molmil
CryoEM structure of Influenza A virus A/Melbourner/1/1946 (H1N1) hemagglutinin bound to GS10-X6-BE4 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GS10-X6-BE4 Fab Heavy chain, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-03-10
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6.
Structure, 2024
5W8U
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BU of 5w8u by Molmil
Crystal structure of MERS-CoV papain-like protease in complex with the C-terminal domain of human ISG15
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ORF1ab, Ubiquitin-like protein ISG15, ...
著者Daczkowski, C.M, Goodwin, O.Y, Dzimianski, J.D, Pegan, S.D.
登録日2017-06-22
公開日2017-09-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.411 Å)
主引用文献Structurally Guided Removal of DeISGylase Biochemical Activity from Papain-Like Protease Originating from Middle East Respiratory Syndrome Coronavirus.
J. Virol., 91, 2017
8F38
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BU of 8f38 by Molmil
Cryo-EM structure of X6 COBRA (H1N1) hemagglutinin bound to CR6261 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR6261 Fab heavy chain, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2022-11-09
公開日2023-12-13
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6.
Structure, 2024
8V7O
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BU of 8v7o by Molmil
Fab fragment of human mAb #58 in complex with computationally optimized broadly reactive H1 influenza hemagglutinin X6
分子名称: #58 heavy chain, #58 light chain, Hemagglutinin
著者Nagashima, K.A, Mousa, J.J.
登録日2023-12-04
公開日2024-04-10
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6.
Structure, 2024

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件を2024-07-10に公開中

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