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1VSG
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BU of 1vsg by Molmil
2.9 ANGSTROMS RESOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF A VARIANT SURFACE GLYCOPROTEIN FROM TRYPANOSOMA BRUCEI
分子名称: VARIANT SURFACE GLYCOPROTEIN MITAT 1.2, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Freymann, D, Down, J, Wiley, D.C.
登録日1990-10-22
公開日1992-01-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献2.9 A resolution structure of the N-terminal domain of a variant surface glycoprotein from Trypanosoma brucei.
J.Mol.Biol., 216, 1990
2V8F
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Mouse Profilin IIa in complex with a double repeat from the FH1 domain of mDia1
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, PROFILIN-2, ...
著者Kursula, P, Kursula, I, Downer, J, Witke, W, Wilmanns, M.
登録日2007-08-07
公開日2007-12-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp.
J.Mol.Biol., 375, 2008
2V8C
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BU of 2v8c by Molmil
Mouse Profilin IIa in complex with the proline-rich domain of VASP
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, PROFILIN-2, ...
著者Kursula, P, Downer, J, Witke, W, Wilmanns, M.
登録日2007-08-06
公開日2007-12-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献High-Resolution Structural Analysis of Mammalian Profilin 2A Complex Formation with Two Physiological Ligands: The Formin Homology 1 Domain of Mdia1 and the Proline-Rich Domain of Vasp.
J.Mol.Biol., 375, 2008
8C3N
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BU of 8c3n by Molmil
Stapled peptide SP30 in complex with humanised RadA mutant HumRadA22
分子名称: 4,6-diethylpyrimidin-2-amine, ADENOSINE-5'-DIPHOSPHATE, Breast cancer type 2 susceptibility protein, ...
著者Pantelejevs, T, Hyvonen, M.
登録日2022-12-27
公開日2023-03-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase.
Chem Sci, 14, 2023
8BR9
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BU of 8br9 by Molmil
Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22
分子名称: 4,6-diethylpyrimidin-2-amine, ADENOSINE-5'-DIPHOSPHATE, Breast cancer type 2 susceptibility protein, ...
著者Pantelejevs, T, Hyvonen, M.
登録日2022-11-22
公開日2023-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献A recombinant approach for stapled peptide discovery yields inhibitors of the RAD51 recombinase.
Chem Sci, 14, 2023
8P08
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BU of 8p08 by Molmil
Crystal structure of human CLK1 in complex with Leucettinib-21
分子名称: (4~{Z})-4-(1,3-benzothiazol-6-ylmethylidene)-2-[[(2~{R})-1-methoxy-4-methyl-pentan-2-yl]amino]-1~{H}-imidazol-5-one, Dual specificity protein kinase CLK1
著者Kraemer, A, Schroeder, M, Meijer, L, Knapp, S, Structural Genomics Consortium (SGC)
登録日2023-05-09
公開日2023-05-17
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer's Disease Drug Candidate.
J.Med.Chem., 66, 2023
6G76
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Phosphorylated RSK4 N-terminal Kinase Domain in complex with AMP-PNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-6, ZINC ION
著者Prischi, F, Ali, M.M.
登録日2018-04-04
公開日2019-04-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.
Sci Transl Med, 13, 2021
6G78
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RSK4 N-terminal Kinase Domain S232E in complex with AMP-PNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-6
著者Prischi, F, Ali, M.M.
登録日2018-04-04
公開日2019-04-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.
Sci Transl Med, 13, 2021
6G77
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BU of 6g77 by Molmil
RSK4 N-terminal Kinase Domain in complex with AMP-PNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribosomal protein S6 kinase alpha-6, ZINC ION
著者Prischi, F, Ali, M.M.
登録日2018-04-04
公開日2019-04-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer.
Sci Transl Med, 13, 2021
3KCG
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BU of 3kcg by Molmil
Crystal structure of the antithrombin-factor IXa-pentasaccharide complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, Antithrombin-III, ...
著者Huntington, J.A, Johnson, D.J.D.
登録日2009-10-21
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis of factor IXa recognition by heparin-activated antithrombin revealed by a 1.7-A structure of the ternary complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
1T1F
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BU of 1t1f by Molmil
Crystal Structure of Native Antithrombin in its Monomeric Form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, GLYCEROL, ...
著者Johnson, D.J.D, Huntington, J.A.
登録日2004-04-16
公開日2005-10-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation
J.Biol.Chem., 281, 2006

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件を2024-11-06に公開中

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