8P08

Crystal structure of human CLK1 in complex with Leucettinib-21

Summary for 8P08

• Entry DOI: 10.2210/pdb8p08/pdb
• Descriptor: Dual specificity protein kinase CLK1, (4~{Z})-4-(1,3-benzothiazol-6-ylmethylidene)-2-[[(2~{R})-1-methoxy-4-methyl-pentan-2-yl]amino]-1~{H}-imidazol-5-one (3 entities in total)
• Functional Keywords: kinase, typ1 inhibitor, clk1, structural genomics, structural genomics consortium, sgc, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39939.97

Authors

Kraemer, A.,Schroeder, M.,Meijer, L.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2023-05-09, release date: 2023-05-17)

• Primary citation: Kraemer, A.,Schroeder, M.,Meijer, L.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal structure of human CLK1 bound in complex with Leucettinib-21; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)