2AH2
| Trypanosoma cruzi trans-sialidase in complex with 2,3-difluorosialic acid (covalent intermediate) | 分子名称: | 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CHLORIDE ION, GLYCEROL, ... | 著者 | Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M. | 登録日 | 2005-07-27 | 公開日 | 2005-08-23 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase Structure, 12, 2004
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1S0I
| Trypanosoma cruzi trans-sialidase in complex with sialyl-lactose (Michaelis complex) | 分子名称: | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, trans-sialidase | 著者 | Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M. | 登録日 | 2003-12-31 | 公開日 | 2004-05-18 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase. Structure, 12, 2004
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1U33
| In situ extension as an approach for identifying novel alpha-amylase inhibitors | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4'-O-METHYL-MALTOSYL-ALPHA (1,4)-(Z, 3S,4S,5R,6R)-3,4,5-TRIHYDROXY-6-HYDROXYMETHYL-PIPERIDIN-2-ONE, ... | 著者 | Numao, S, Li, C, Damager, I, Wrodnigg, T.M, Begum, A, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2004-07-20 | 公開日 | 2004-09-07 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | In Situ Extension as an Approach for Identifying Novel alpha-Amylase Inhibitors. J.Biol.Chem., 279, 2004
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1U30
| In situ extension as an approach for identifying novel alpha-amylase inhibitors, structure containing maltosyl-alpha (1,4)-D-gluconhydroximo-1,5-lactam | 分子名称: | (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ... | 著者 | Numao, S, Li, C, Damager, I, Wrodnigg, T.M, Begum, A, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2004-07-20 | 公開日 | 2004-09-07 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | In Situ Extension as an Approach for Identifying Novel alpha-Amylase Inhibitors. J.Biol.Chem., 279, 2004
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1S0J
| Trypanosoma cruzi trans-sialidase in complex with MuNANA (Michaelis complex) | 分子名称: | 4-METHYL-2-OXO-2H-CHROMEN-7-YL 5-(ACETYLAMINO)-3,5-DIDEOXY-L-ERYTHRO-NON-2-ULOPYRANOSIDONIC ACID, trans-sialidase | 著者 | Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M. | 登録日 | 2003-12-31 | 公開日 | 2004-05-18 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase. Structure, 12, 2004
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1U2Y
| In situ extension as an approach for identifying novel alpha-amylase inhibitors, structure containing D-gluconhydroximo-1,5-lactam | 分子名称: | (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ... | 著者 | Numao, S, Li, C, Damager, I, Wrodnigg, T.M, Begum, A, Overall, C.M, Brayer, G.D, Withers, S.G. | 登録日 | 2004-07-20 | 公開日 | 2004-09-07 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | In Situ Extension as an Approach for Identifying Novel alpha-Amylase Inhibitors. J.Biol.Chem., 279, 2004
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