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7UGM
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BU of 7ugm by Molmil
Crystal Structure of BG24-iGL CDR3mat Fab
分子名称: BG24-iGL CDR3mat Fab heavy chain, BG24-iGL CDR3mat Fab light chain
著者Dam, K.A, Barnes, C.O, Bjorkman, P.J.
登録日2022-03-25
公開日2022-11-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGQ
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BU of 7ugq by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline CDRL1 and 10-1074 Fabs in complex with HIV-1 Env 6405-SOSIP.664
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dam, K.A, Bjorkman, P.J.
登録日2022-03-25
公開日2022-11-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGP
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BU of 7ugp by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 containing the N276 gp120 glycan- Class 1
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dam, K.A, Bjorkman, P.J.
登録日2022-03-25
公開日2022-11-09
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGN
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BU of 7ugn by Molmil
Cryo-EM structure of BG24 inferred germline Fabs with germline CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 - Class 1
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dam, K.A, Bjorkman, P.J.
登録日2022-03-25
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGO
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BU of 7ugo by Molmil
Cryo-EM structure of BG24 inferred germline Fabs with mature CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dam, K.A, Bjorkman, P.J.
登録日2022-03-25
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
8EKI
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BU of 8eki by Molmil
CryoEM structure of the Dsl1 complex bound to SNAREs Sec20 and Use1
分子名称: Protein transport protein DSL1, Protein transport protein SEC20, Protein transport protein SEC39, ...
著者DAmico, K.A, Jeffrey, P.D, Hughson, F.M.
登録日2022-09-21
公開日2023-10-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
8FYI
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BU of 8fyi by Molmil
Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(6-8)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Fan, C, Dam, K.A, Bjorkman, P.J.
登録日2023-01-26
公開日2023-10-18
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
Nature, 623, 2023
8FYJ
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BU of 8fyj by Molmil
Structure of HIV-1 BG505 SOSIP-HT2 in complex with two CD4 molecules (class I)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Fan, C, Dam, K.A, Bjorkman, P.J.
登録日2023-01-26
公開日2023-10-18
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Intermediate conformations of CD4-bound HIV-1 Env heterotrimers.
Nature, 623, 2023
7K8P
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BU of 7k8p by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C110
分子名称: C110 Fab Heavy Chain, C110 Fab Light Chain
著者Dam, K.A, Barnes, C.O, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8V
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BU of 7k8v by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C110
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C110 Fab Heavy Chain, ...
著者Dam, K.A, Barnes, C.O, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
8FTU
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BU of 8ftu by Molmil
Crystal structure of the SNARE Use1 bound to Dsl1 complex subunits Sec39 and Dsl1, Revised Use1 structure
分子名称: Protein transport protein DSL1, Protein transport protein SEC39, Vesicle transport protein USE1
著者Travis, S.M, Jeffrey, P.D, Hughson, F.M.
登録日2023-01-13
公開日2023-03-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (5.73 Å)
主引用文献Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
7TQG
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BU of 7tqg by Molmil
Crystal Structure of IOMA Fab inferred germline
分子名称: IOMA iGL Fab Heavy Chain, IOMA iGL Fab Light Chain
著者Gristick, H.B, Bjorkman, P.J.
登録日2022-01-26
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.
Sci Immunol, 8, 2023
8D5C
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BU of 8d5c by Molmil
anti-HIV-1 gp120-sCD4 complex antibody CG10 Fab in complex with B41-sCD4
分子名称: CG10 Fab heavy chain, CG10 Fab light chain, Envelope glycoprotein gp160, ...
著者Yang, Z, Bjorkman, P.J, Gershoni, J.M.
登録日2022-06-04
公開日2022-11-16
最終更新日2023-01-04
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers.
J.Virol., 96, 2022
8D54
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BU of 8d54 by Molmil
anti HIV gp120/CD4 complex antibody CG10 Fab
分子名称: CG10 Fab heavy chain, CG10 Fab light chain
著者Yang, Z, Bjorkman, P.J.
登録日2022-06-03
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Antibody Recognition of CD4-Induced Open HIV-1 Env Trimers.
J.Virol., 96, 2022
7TFN
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BU of 7tfn by Molmil
Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-HIV-1 CD4bs antibody Fab Ab1303 - Heavy chain, ...
著者Yang, Z, Bjorkman, P.J.
登録日2022-01-06
公開日2022-01-19
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7TFO
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BU of 7tfo by Molmil
Cryo-EM structure of HIV-1 Env trimer BG505 SOSIP.664 in complex with CD4bs antibody Ab1573
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4 binding site antibody Ab1573 - Fab heavy chain, ...
著者Yang, Z, Bjorkman, P.J.
登録日2022-01-06
公開日2022-01-26
最終更新日2022-02-23
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7RYV
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BU of 7ryv by Molmil
Anti-HIV neutralizing antibody Ab1573 Fab isolated from sequentially immunized macaques
分子名称: Ab1573 Fab heavy chain, Ab1573 Fab light chain
著者Yang, Z, Bjorkman, P.J.
登録日2021-08-26
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7RYU
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BU of 7ryu by Molmil
Anti-HIV neutralizing antibody Ab1303 Fab isolated from sequentially immunized mcaques
分子名称: Ab1303 Fab heavy chain, Ab1303 Fab light chain
著者Yang, Z, Bjorkman, P.J.
登録日2021-08-26
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7K8T
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BU of 7k8t by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C002 (State 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ...
著者Malyutin, A.G, Barnes, C.O, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8N
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BU of 7k8n by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C102
分子名称: C102 Fab Heavy Chain, C102 Fab Light Chain, DI(HYDROXYETHYL)ETHER, ...
著者Jette, C.A, Barnes, C.O, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8X
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BU of 7k8x by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ...
著者Abernathy, M.E, Barnes, C.O, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8Q
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BU of 7k8q by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C121
分子名称: C121 Fab Heavy Chain, C121 Fab Light Chain, GLYCEROL
著者Abernathy, M.E, Barnes, C.O, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8Y
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BU of 7k8y by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ...
著者Abernathy, M.E, Barnes, C.O, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8S
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BU of 7k8s by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C002 (state 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ...
著者Barnes, C.O, Malyutin, A.G, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8R
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BU of 7k8r by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C135
分子名称: C135 Fab Heavy Chain, C135 Fab Light Chain, GLYCEROL
著者Jette, C.A, Barnes, C.O, Bjorkman, P.J.
登録日2020-09-27
公開日2020-10-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020

 

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