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1MFG
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BU of 1mfg by Molmil
The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor
分子名称: Erb-B2 INTERACTING PROTEIN, Erb-B2 carboxyl-terminal fragment
著者Birrane, G, Chung, J, Ladias, J.A.
登録日2002-08-10
公開日2003-01-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Novel mode of ligand recognition by the erbin PDZ domain
J.Biol.Chem., 278, 2003
1MFL
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BU of 1mfl by Molmil
The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor
分子名称: Erb-B2 INTERACTING PROTEIN, PHOSPHORYLATED Erb-B2 carboxyl-terminal fragment.
著者Birrane, G, Chung, J, Ladias, J.A.
登録日2002-08-12
公開日2003-01-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Novel mode of ligand recognition by the erbin PDZ domain
J.Biol.Chem., 278, 2003
1KBH
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BU of 1kbh by Molmil
Mutual Synergistic Folding in the Interaction Between Nuclear Receptor Coactivators CBP and ACTR
分子名称: CREB-BINDING PROTEIN, nuclear receptor coactivator
著者Demarest, S.J, Martinez-Yamout, M, Chung, J, Chen, H, Xu, W, Dyson, H.J, Evans, R.M, Wright, P.E.
登録日2001-11-06
公開日2002-02-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators.
Nature, 415, 2002
1DGQ
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BU of 1dgq by Molmil
NMR SOLUTION STRUCTURE OF THE INSERTED DOMAIN OF HUMAN LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1
分子名称: LEUKOCYTE FUNCTION ASSOCIATED ANTIGEN-1
著者Legge, G.B, Kriwacki, R.W, Chung, J, Hommel, U, Ramage, P, Case, D.A, Dyson, H.J, Wright, P.E.
登録日1999-11-24
公開日2000-02-03
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of the inserted domain of human leukocyte function associated antigen-1.
J.Mol.Biol., 295, 2000
1IE5
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BU of 1ie5 by Molmil
NMR STRUCTURE OF THE THIRD IMMUNOGLOBULIN DOMAIN FROM THE NEURAL CELL ADHESION MOLECULE.
分子名称: NEURAL CELL ADHESION MOLECULE
著者Atkins, A.R, Chung, J, Deechongkit, S, Little, E.B, Edelman, G.M, Wright, P.E, Cunningham, B.A, Dyson, H.J.
登録日2001-04-06
公開日2001-08-08
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding?
J.Mol.Biol., 311, 2001
3NQW
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BU of 3nqw by Molmil
A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses
分子名称: CG11900, MANGANESE (II) ION, SULFATE ION
著者Sun, D.W, Kim, H.Y, Kim, K.J, Jeon, Y.H, Chung, J.
登録日2010-06-30
公開日2010-09-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses
Nat.Struct.Mol.Biol., 17, 2010
3NR1
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BU of 3nr1 by Molmil
A metazoan ortholog of SpoT hydrolyzes ppGpp and plays a role in starvation responses
分子名称: HD domain-containing protein 3, MANGANESE (II) ION
著者Sun, D.W, Kim, H.Y, Kim, K.J, Jeon, Y.H, Chung, J.
登録日2010-06-30
公開日2010-09-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses
Nat.Struct.Mol.Biol., 17, 2010
3P2F
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BU of 3p2f by Molmil
Crystal structure of TofI in an apo form
分子名称: AHL synthase
著者Yu, S, Rhee, S.
登録日2010-10-02
公開日2011-07-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase
Proc.Natl.Acad.Sci.USA, 108, 2011
3P2H
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BU of 3p2h by Molmil
Crystal structure of TofI in a ternary complex with an inhibitor and MTA
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, AHL synthase, N-(3-oxocyclohex-1-en-1-yl)octanamide
著者Yu, S, Rhee, S.
登録日2010-10-02
公開日2011-07-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Small-molecule inhibitor binding to an N-acyl-homoserine lactone synthase
Proc.Natl.Acad.Sci.USA, 108, 2011
8DD5
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BU of 8dd5 by Molmil
Crystal structure of KAT6A in complex with inhibitor CTx-648 (PF-9363)
分子名称: 2,6-dimethoxy-N-{4-methoxy-6-[(1H-pyrazol-1-yl)methyl]-1,2-benzoxazol-3-yl}benzene-1-sulfonamide, Histone acetyltransferase KAT6A, ZINC ION
著者Greasley, S.E, Johnson, E, Brodsky, O.
登録日2022-06-17
公開日2023-07-05
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Targeting KAT6A/KAT6B dependencies in breast cancer with a novel selective, orally bioavailable KAT6 inhibitor, CTx-648/PF-9363
To Be Published
8CX9
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BU of 8cx9 by Molmil
Structure of the SARS-COV2 PLpro (C111S) in complex with a dimeric Ubv that inhibits activity by an unusual allosteric mechanism
分子名称: BROMIDE ION, CHLORIDE ION, Papain-like protease nsp3, ...
著者Singer, A.U, Slater, C.L, Patel, A, Russel, R, Mark, B.L, Sidhu, S.S.
登録日2022-05-20
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site.
Plos Pathog., 18, 2022
1CUR
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BU of 1cur by Molmil
REDUCED RUSTICYANIN, NMR
分子名称: COPPER (II) ION, CU(I) RUSTICYANIN
著者Botuyan, M.V, Dyson, H.J.
登録日1996-04-19
公開日1996-11-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure of Cu(I) rusticyanin from Thiobacillus ferrooxidans: structural basis for the extreme acid stability and redox potential.
J.Mol.Biol., 263, 1996
8FAU
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BU of 8fau by Molmil
Masking thiol reactivity with thioamide-based MBPs- carbonic anhydrase II complexed with 4-phenylthiazole-2(3H)-thione
分子名称: 4-phenyl-1,3-thiazole-2(3H)-thione, Carbonic anhydrase 2, SULFATE ION, ...
著者Kohlbrand, A.J, Seo, H.
登録日2022-11-28
公開日2023-03-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Masking thiol reactivity with thioamide, thiourea, and thiocarbamate-based MBPs.
Chem.Commun.(Camb.), 59, 2023
8FAL
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BU of 8fal by Molmil
Masking thiol reactivity with thioamide-based MBPs- carbonic anhydrase II complexed with benzo[d]thiazole-2(3H)-thione
分子名称: 1,3-benzothiazole-2(3H)-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者Kohlbrand, A.J, Seo, H.
登録日2022-11-28
公開日2023-03-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Masking thiol reactivity with thioamide, thiourea, and thiocarbamate-based MBPs.
Chem.Commun.(Camb.), 59, 2023
7M3Q
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BU of 7m3q by Molmil
Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV)
分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, ...
著者Chowdhury, A, Singer, A.U, Ogunjimi, A.A, Teyra, J, Zhang, W, Sicheri, F, Sidhu, S.S.
登録日2021-03-18
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the Smurf2 HECT Domain with a High Affinity Ubiquitin Variant (UbV)
To be published
3E74
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BU of 3e74 by Molmil
Crystal structure of E. coli allantoinase with iron ions at the metal center
分子名称: Allantoinase, FE (III) ION
著者Kim, K.
登録日2008-08-17
公開日2009-02-24
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of metal-dependent allantoinase from Escherichia coli
J.Mol.Biol., 387, 2009
5X6R
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BU of 5x6r by Molmil
Crystal structure of Saccharomyces cerevisiae KMO in complex with Ro 61-8048
分子名称: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
著者Kim, H.T, Hwang, K.Y.
登録日2017-02-23
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.911 Å)
主引用文献Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase
Cell Chem Biol, 25, 2018
5X68
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BU of 5x68 by Molmil
Crystal Structure of Human KMO
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
著者Kim, H.T, Hwang, K.Y.
登録日2017-02-21
公開日2018-02-21
最終更新日2018-05-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase
Cell Chem Biol, 25, 2018
5X6P
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BU of 5x6p by Molmil
Crystal structure of Pseudomonas fluorescens KMO
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
著者Kim, H.T, Hwang, K.Y.
登録日2017-02-22
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase
Cell Chem Biol, 25, 2018
5X6Q
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BU of 5x6q by Molmil
Crystal structure of Pseudomonas fluorescens KMO in complex with Ro 61-8048
分子名称: 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
著者Kim, H.T, Hwang, K.Y.
登録日2017-02-23
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.897 Å)
主引用文献Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase
Cell Chem Biol, 25, 2018
5YCX
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BU of 5ycx by Molmil
X-Ray Structure of Enoyl-Acyl Carrier Protein Reductase from Bacillus Anthracis with c-terminal His tag (Apo form)
分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
著者Kim, H.T.
登録日2017-09-08
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Structural insights into the dimer-tetramer transition of FabI from Bacillus anthracis
Biochem. Biophys. Res. Commun., 493, 2017
5YCS
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BU of 5ycs by Molmil
X-Ray Structure of Enoyl-Acyl Carrier Protein Reductase from Bacillus Anthracis with triclosan
分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
著者Kim, H.T.
登録日2017-09-08
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural insights into the dimer-tetramer transition of FabI from Bacillus anthracis
Biochem. Biophys. Res. Commun., 493, 2017
5YCR
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BU of 5ycr by Molmil
X-Ray Structure of Enoyl-Acyl Carrier Protein Reductase from Bacillus Anthracis with NAD+
分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION
著者Kim, H.T.
登録日2017-09-08
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural insights into the dimer-tetramer transition of FabI from Bacillus anthracis
Biochem. Biophys. Res. Commun., 493, 2017
5YCV
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BU of 5ycv by Molmil
X-Ray Structure of Enoyl-Acyl Carrier Protein Reductase from Bacillus Anthracis (Apo form)
分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
著者Kim, H.T.
登録日2017-09-08
公開日2018-02-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Structural insights into the dimer-tetramer transition of FabI from Bacillus anthracis
Biochem. Biophys. Res. Commun., 493, 2017
1A3Z
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BU of 1a3z by Molmil
REDUCED RUSTICYANIN AT 1.9 ANGSTROMS
分子名称: COPPER (I) ION, RUSTICYANIN
著者Zhao, D, Shoham, M.
登録日1998-01-27
公開日1998-07-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rusticyanin: Extremes in acid stability and redox potential explained by the crystal structure.
Biophys.J., 74, 1998

 

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