6AEZ
 
 | | Crystal structure of human CCL5 trimer | | 分子名称: | C-C motif chemokine 5, SULFATE ION | | 著者 | Chen, Y.C, Li, K.M, Chen, P.J, Zarivach, R, Sun, Y.J, Sue, S.C. | | 登録日 | 2018-08-07 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Integrative Model to Coordinate the Oligomerization and Aggregation Mechanisms of CCL5.
J.Mol.Biol., 432, 2020
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6LSQ
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6LOG
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3CLH
 | | Crystal structure of 3-dehydroquinate synthase (DHQS)from Helicobacter pylori | | 分子名称: | 3-dehydroquinate synthase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | | 著者 | Wang, W.C, Liu, J.S, Cheng, W.C, Wang, H.J, Chen, Y.C. | | 登録日 | 2008-03-19 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-based inhibitor discovery of Helicobacter pylori dehydroquinate synthase.
Biochem.Biophys.Res.Commun., 373, 2008
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2PJG
 | | Solution structure of rhodostomin D51E mutant | | 分子名称: | Rhodostoxin-disintegrin rhodostomin | | 著者 | Chuang, W.J, Chen, Y.C, Chen, C.Y, Chou, L.J. | | 登録日 | 2007-04-16 | | 公開日 | 2007-05-08 | | 最終更新日 | 2021-11-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Effect of D to E mutation of the RGD motif in rhodostomin on its activity, structure, and dynamics: Importance of the interactions between the D residue and integrin
Proteins, 2009
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2PJF
 | | Solution structure of rhodostomin | | 分子名称: | Rhodostoxin-disintegrin rhodostomin | | 著者 | Chuang, W.J, Chen, Y.C, Chen, C.Y, Chang, Y.T. | | 登録日 | 2007-04-16 | | 公開日 | 2007-05-08 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Effect of D to E mutation of the RGD motif in rhodostomin on its activity, structure, and dynamics: Importance of the interactions between the D residue and integrin
Proteins, 2009
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2LA1
 | | Expression in Pichia pastoris and backbone dynamics of dendroaspin, a three finger toxin | | 分子名称: | Mambin | | 著者 | Chuang, W.J, Cheng, C.H, Chen, Y.C, Shiu, J.H. | | 登録日 | 2011-03-01 | | 公開日 | 2012-03-07 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Dynamics and functional differences between dendroaspin and rhodostomin: Insights into protein scaffolds in integrin recognition
Protein Sci., 21, 2012
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4V93
 | | Fitted coordinates for Lumbricus terrestris hemoglobin cryo-EM complex (EMD-2627) | | 分子名称: | EXTRACELLULAR GLOBIN-2, EXTRACELLULAR GLOBIN-3, EXTRACELLULAR GLOBIN-4, ... | | 著者 | Chen, W.T, Chen, Y.C, Liou, H.H, Chao, C.Y. | | 登録日 | 2014-04-16 | | 公開日 | 2014-07-09 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | | 主引用文献 | Structural Basis for Cooperative Oxygen Binding and Bracelet-Assisted Assembly of Lumbricus Terrestris Hemoglobin
To be Published
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5GO3
 | | Crystal structure of a di-nucleotide cyclase Vibrio mutant | | 分子名称: | Cyclic GMP-AMP synthase | | 著者 | Ming, Z.H, Wang, W, Xie, Y.C, Chen, Y.C, Yan, L.M, Lou, Z.Y. | | 登録日 | 2016-07-26 | | 公開日 | 2016-11-02 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a di-nucleotide cyclase Vibrio mutant
To Be Published
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1Q7J
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1Q7I
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3UCI
 | | Crystal structure of Rhodostomin ARLDDL mutant | | 分子名称: | disintegrin | | 著者 | Shiu, J.H, Chen, C.Y, Chen, Y.C, Chang, Y.T, Chang, Y.S, Huang, C.H, Chuang, W.J. | | 登録日 | 2011-10-27 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Design of Integrin AlphaVbeta3-Specific Disintegrin for Cancer Therapy
To be Published
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6KY5
 | | Crystal structure of a hydrolase mutant | | 分子名称: | PET hydrolase, SULFATE ION | | 著者 | Cui, Y.L, Chen, Y.C, Liu, X.Y, Dong, S.J, Han, J, Xiang, H, Chen, Q, Liu, H.Y, Han, X, Liu, W.D, Tang, S.Y, Wu, B. | | 登録日 | 2019-09-16 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.631 Å) | | 主引用文献 | Computational redesign of PETase for plasticbiodegradation by GRAPE strategy.
Biorxiv, 2020
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2LUN
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4PE8
 | | Crystal structure of TatD in complex with trinucleotide DNA | | 分子名称: | DNA (5'-D(*GP*CP*T)-3'), Tat-linked quality control protein TatD | | 著者 | Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S. | | 登録日 | 2014-04-23 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.894 Å) | | 主引用文献 | Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
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4P5U
 | | Crystal structure of TatD | | 分子名称: | Tat-linked quality control protein TatD | | 著者 | Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S. | | 登録日 | 2014-03-20 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
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5YAM
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5L6P
 | | EphB3 kinase domain covalently bound to an irreversible inhibitor (compound 6) | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Ephrin type-B receptor 3, ~{N}-(4-phenylazanylquinazolin-7-yl)ethanamide | | 著者 | Schimpl, M, Overman, R, Kung, A, Chen, Y.-C, Ni, F, Zhu, J, Turner, M, Molina, H, Zhang, C. | | 登録日 | 2016-05-30 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3.
J.Am.Chem.Soc., 138, 2016
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5L6O
 | | EphB3 kinase domain covalently bound to an irreversible inhibitor (compound 3) | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 1-(4-phenylazanylquinazolin-7-yl)ethanone, Ephrin type-B receptor 3 | | 著者 | Schimpl, M, Overman, R, Kung, A, Chen, Y.-C, Ni, F, Zhu, J, Turner, M, Molina, H, Zhang, C. | | 登録日 | 2016-05-30 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Development of Specific, Irreversible Inhibitors for a Receptor Tyrosine Kinase EphB3.
J.Am.Chem.Soc., 138, 2016
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5MJB
 | | Kinase domain of human EphB1, G703C mutant, covalently bound to a quinazoline-based inhibitor | | 分子名称: | 2-chloranyl-~{N}-[4-[(2-chloranyl-5-oxidanyl-phenyl)amino]quinazolin-7-yl]ethanamide, Ephrin type-B receptor 1, SULFATE ION | | 著者 | Kung, A, Schimpl, M, Chen, Y.-C, Overman, R.C, Zhang, C. | | 登録日 | 2016-11-30 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | A Chemical-Genetic Approach to Generate Selective Covalent Inhibitors of Protein Kinases.
ACS Chem. Biol., 12, 2017
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5MJA
 | | Kinase domain of human EphB1 bound to a quinazoline-based inhibitor | | 分子名称: | 2-chloranyl-~{N}-[4-[(2-chloranyl-5-oxidanyl-phenyl)amino]quinazolin-7-yl]ethanamide, Ephrin type-B receptor 1, SULFATE ION | | 著者 | Kung, A, Schimpl, M, Chen, Y.-C, Overman, R.C, Zhang, C. | | 登録日 | 2016-11-30 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | A Chemical-Genetic Approach to Generate Selective Covalent Inhibitors of Protein Kinases.
ACS Chem. Biol., 12, 2017
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1JXS
 | | Solution Structure of the DNA-Binding Domain of Interleukin Enhancer Binding Factor | | 分子名称: | interleukin enhancer binding factor | | 著者 | Chuang, W.J, Liu, P.P, Li, C, Hsieh, Y.H, Chen, S.W, Chen, S.H, Jeng, W.Y. | | 登録日 | 2001-09-08 | | 公開日 | 2003-03-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a)
PROTEINS: STRUCT.,FUNCT.,GENET., 49, 2002
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1PSJ
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4QUC
 | | Crystal structure of chromodomain of Rhino | | 分子名称: | RE36324p | | 著者 | Li, S, Patel, D.J. | | 登録日 | 2014-07-10 | | 公開日 | 2014-08-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.502 Å) | | 主引用文献 | Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing.
Genes Dev., 28, 2014
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4QUF
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