7MLH
 
 | | Crystal structure of human IgE (2F10) in complex with Der p 2.0103 | | 分子名称: | CHLORIDE ION, Der p 2 variant 3, IgE Heavy chain, ... | | 著者 | Khatri, K, Kapingidza, A.B, Richardson, C.M, Vailes, L.D, Wunschmann, S, Dolamore, C, Chapman, M.D, Smith, S.A, Pomes, A, Chruszcz, M. | | 登録日 | 2021-04-28 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo.
Pnas Nexus, 1, 2022
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6OY4
 | | Crystal structure of complex between recombinant Der p 2.0103 and Fab fragment of 7A1 | | 分子名称: | Der p 2 variant 3, Fab fragment of IgG, HEAVY CHAIN, ... | | 著者 | Kapingidza, A.B, Offermann, L.R, Glesner, J, Wunschmann, S, Vailes, L.D, Chapman, M.D.C, Pomes, A, Chruszcz, M. | | 登録日 | 2019-05-14 | | 公開日 | 2019-08-28 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy.
J Immunol., 203, 2019
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5VPH
 | | CRYSTAL STRUCTURE OF DER P 1 COMPLEXED WITH FAB 4C1 | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Der p 1 allergen, ... | | 著者 | Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W. | | 登録日 | 2017-05-05 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens.
J.Biol.Chem., 287, 2012
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5VCN
 | | THE CRYSTAL STRUCTURE OF DER P 1 ALLERGEN COMPLEXED WITH FAB FRAGMENT OF MAB 5H8 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Osinski, T, Majorek, K.A, Pomes, A, Offermann, L.R, Osinski, S, Glesner, J, Vailes, L.D, Chapman, M.D, Minor, W, Chruszcz, M. | | 登録日 | 2017-03-31 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.
J. Immunol., 195, 2015
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5VPG
 | | CRYSTAL STRUCTURE OF DER P 1 COMPLEXED WITH FAB 4C1 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W. | | 登録日 | 2017-05-05 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens.
J.Biol.Chem., 287, 2012
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5VPL
 | | CRYSTAL STRUCTURE OF DER F 1 COMPLEXED WITH FAB 4C1 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C1 - HEAVY CHAIN, ... | | 著者 | Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W. | | 登録日 | 2017-05-05 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular Determinants For Antibody Binding On Group 1 House Dust Mite Allergens.
J.Biol.Chem., 287, 2012
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5VCO
 | | THE CRYSTAL STRUCTURE OF DER P 1 ALLERGEN COMPLEXED WITH FAB FRAGMENT OF MAB 10B9 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HEAVY CHAIN OF FAB FRAGMENT OF 10B9 ANTIBODY, ... | | 著者 | Osinski, T, Majorek, K.A, Pomes, A, Offermann, L.R, Osinski, S, Glesner, J, Vailes, L.D, Chapman, M.D, Minor, W, Chruszcz, M. | | 登録日 | 2017-03-31 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.
J. Immunol., 195, 2015
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5VPK
 | | CRYSTAL STRUCTURE OF MITE ALLERGEN DER F 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Der f 1 variant, SULFATE ION | | 著者 | Chruszcz, M, Chapman, M.D, Vailes, L.D, Pomes, A, Minor, W. | | 登録日 | 2017-05-05 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures Of Mite Allergens Der F 1 And Der P 1 Reveal Differences In Surface-Exposed Residues That May Influence Antibody Binding
J.Mol.Biol., 386, 2009
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3MQ1
 | | Crystal Structure of Dust Mite Allergen Der p 5 | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Mite allergen Der p 5, ... | | 著者 | Mueller, G.A, Gosavi, R.A, Krahn, J.M, Edwards, L.L, Cuneo, M.J, Glesner, J, Pomes, A, Chapman, M.D, London, R.E, Pedersen, L.C. | | 登録日 | 2010-04-27 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Der p 5 crystal structure provides insight into the group 5 dust mite allergens.
J.Biol.Chem., 285, 2010
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4JRB
 | | Structure of Cockroach Allergen Bla g 1 Tandem Repeat as a EGFP fusion | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, CHLORIDE ION, DODECANE, ... | | 著者 | Mueller, G.A, Pedersen, L.C, Lih, F.B, Glesner, J, Moon, A.F, Chapman, M.D, Tomer, K, London, R.E. | | 登録日 | 2013-03-21 | | 公開日 | 2013-07-24 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.414 Å) | | 主引用文献 | The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment.
J.Allergy Clin.Immunol., 132, 2013
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3RVU
 | | Structure of 4C1 Fab in C2221 space group | | 分子名称: | 4C1 Fab - heavy chain, 4C1 Fab - light chain | | 著者 | Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W. | | 登録日 | 2011-05-06 | | 公開日 | 2012-01-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular determinants for antibody binding on group 1 house dust mite allergens.
J.Biol.Chem., 287, 2012
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3V0R
 | | Crystal structure of Alternaria alternata allergen Alt a 1 | | 分子名称: | 2,5,6-triaminopyrimidin-4-ol, 8-aminooctanoic acid, Major allergen Alt a 1, ... | | 著者 | Chruszcz, M, Solberg, R, Osinski, T, Chapman, M.D, Minor, W. | | 登録日 | 2011-12-08 | | 公開日 | 2012-06-13 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Alternaria alternata allergen Alt a 1: a unique beta-barrel protein dimer found exclusively in fungi.
J.Allergy Clin.Immunol., 130, 2012
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3RVT
 | | Structure of 4C1 Fab in P212121 space group | | 分子名称: | Fab fragment of 4C1 antibody - heavy chain, Fab fragment of 4C1 antibody - light chain | | 著者 | Chruszcz, M, Vailes, L.D, Chapman, M.D, Pomes, A, Minor, W. | | 登録日 | 2011-05-06 | | 公開日 | 2012-01-11 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Molecular determinants for antibody binding on group 1 house dust mite allergens.
J.Biol.Chem., 287, 2012
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4ZCE
 | | Crystal Structure of the dust mite allergen Der p 23 from Dermatophagoides pteronyssinus | | 分子名称: | 1,2-ETHANEDIOL, Dust mite allergen | | 著者 | Pedersen, L.C, Mueller, G.A, Randall, T.A, Glesner, J, Perera, L, Edwards, L.L, Chapman, M.D, London, R.E, Pomes, A. | | 登録日 | 2015-04-15 | | 公開日 | 2015-11-25 | | 最終更新日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Serological, genomic and structural analyses of the major mite allergen Der p 23.
Clin Exp Allergy, 46, 2016
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4POZ
 | | Fab fragment of Der p 1 specific antibody 10B9 | | 分子名称: | heavy chain of Fab fragment of 10B9 antibody, light chain of Fab fragment of 10B9 antibody | | 著者 | Osinski, T, Majorek, K.A, Pomes, A, Offermann, L.R, Osinski, S, Glesner, J, Vailes, L.D, Chapman, M.D, Minor, W, Chruszcz, M. | | 登録日 | 2014-02-26 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Analysis of Der p 1-Antibody Complexes and Comparison with Complexes of Proteins or Peptides with Monoclonal Antibodies.
J. Immunol., 195, 2015
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8VK1
 | | X-ray crystal structure of human IgE 4C8 Fab complex with Der p 2.0103 | | 分子名称: | Der p 2 variant 3, IgE 4C8 heavy chain, IgE 4C8 light chain | | 著者 | Khatri, K, Ball, A, Smith, S.A, Champan, M.D, Pomes, A, Chruszcz, M. | | 登録日 | 2024-01-08 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2.
J.Allergy Clin.Immunol., 2024
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8VK2
 | | X-ray crystal structure of human IgE 4C8 Fab | | 分子名称: | IgE 4C8 heavy chain, IgE 4C8 light chain | | 著者 | Khatri, K, Ball, A, Smith, S.A, Champan, M.D, Pomes, A, Chruszcz, M. | | 登録日 | 2024-01-08 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.508 Å) | | 主引用文献 | Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2.
J.Allergy Clin.Immunol., 2024
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3LIZ
 | | crystal structure of bla g 2 complexed with Fab 4C3 | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4C3 monoclonal antibody Heavy Chain, ... | | 著者 | Li, M, Gustchina, A, Glesner, J, Wunschmann, S, Pomes, A, Wlodawer, A. | | 登録日 | 2010-01-25 | | 公開日 | 2010-12-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding.
Plos One, 6, 2011
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3F5V
 | | C2 Crystal form of mite allergen DER P 1 | | 分子名称: | CALCIUM ION, Der p 1 allergen, HEXAETHYLENE GLYCOL | | 著者 | Stura, E.A, Minor, W, Chruszcz, M, Saint Remy, J.M. | | 登録日 | 2008-11-04 | | 公開日 | 2009-02-10 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Crystal structures of mite allergens Der f 1 and Der p 1 reveal differences in surface-exposed residues that may influence antibody binding.
J.Mol.Biol., 386, 2009
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3H4Z
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1YG9
 | | The structure of mutant (N93Q) of bla g 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aspartic protease Bla g 2, ... | | 著者 | Li, M, Gustchina, A, Wuenschmann, S, Pomes, A, Wlodawer, A. | | 登録日 | 2005-01-04 | | 公開日 | 2005-03-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structure of cockroach allergen Bla g 2, an unusual zinc binding aspartic protease with a novel mode of self-inhibition.
J.Mol.Biol., 348, 2005
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2NR6
 | | Crystal structure of the complex of antibody and the allergen Bla g 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody heavy chain, ... | | 著者 | Li, M, Gustchina, A, Wlodawer, A, Pomes, A, Wunschmann, S. | | 登録日 | 2006-11-01 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Crystal structure of a dimerized cockroach allergen Bla g 2 complexed with a monoclonal antibody.
J.Biol.Chem., 283, 2008
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1A9V
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