6OY4

Crystal structure of complex between recombinant Der p 2.0103 and Fab fragment of 7A1

Summary for 6OY4

• Entry DOI: 10.2210/pdb6oy4/pdb
• Descriptor: Der p 2 variant 3, Fab fragment of IgG, LIGHT CHAIN, Fab fragment of IgG, HEAVY CHAIN, ... (5 entities in total)
• Functional Keywords: allergen, dust mite, antibody binding, allergen-immune system complex, allergen/immune system
• Biological source: Dermatophagoides pteronyssinus (European house dust mite); More
• Total number of polymer chains: 3
• Total formula weight: 61718.97

Authors

Kapingidza, A.B.,Offermann, L.R.,Glesner, J.,Wunschmann, S.,Vailes, L.D.,Chapman, M.D.C.,Pomes, A.,Chruszcz, M. (deposition date: 2019-05-14, release date: 2019-08-28, Last modification date: 2023-10-11)

• Primary citation: Glesner, J.,Kapingidza, A.B.,Godzwon, M.,Offermann, L.R.,Mueller, G.A.,DeRose, E.F.,Wright, P.,Richardson, C.M.,Woodfolk, J.A.,Vailes, L.D.,Wunschmann, S.,London, R.E.,Chapman, M.D.,Ohlin, M.,Chruszcz, M.,Pomes, A.; A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy.; J Immunol., 203:2545-2556, 2019; PubMed: 31554696; DOI: 10.4049/jimmunol.1900580

Experimental method

X-RAY DIFFRACTION (2.45 Å)