7KX0
 
 | | Crystal structure of the CD27:CD70 co-stimulatory complex | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, ... | | 著者 | Maben, Z, Liu, W, Mosyak, L, Chaparro-Riggers, J. | | 登録日 | 2020-12-02 | | 公開日 | 2021-09-08 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex.
J.Biol.Chem., 297, 2021
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3SQO
 | | PCSK9 J16 Fab complex | | 分子名称: | J16 Heavy chain, J16 Light chain, PCSK9 prodomain, ... | | 著者 | Strop, P. | | 登録日 | 2011-07-05 | | 公開日 | 2012-05-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates.
J.Pharmacol.Exp.Ther., 340, 2012
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4DZ8
 | | human IgG1 Fc fragment Heterodimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | | 著者 | Strop, P. | | 登録日 | 2012-02-29 | | 公開日 | 2012-08-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Generating Bispecific Human IgG1 and IgG2 Antibodies from Any Antibody Pair.
J.Mol.Biol., 420, 2012
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6UUP
 | | Structure of anti-hCD33 conditional scFv | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Anti-CD33 conditional scFv, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kimberlin, C.R, Park, S. | | 登録日 | 2019-10-31 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.20001864 Å) | | 主引用文献 | Direct control of CAR T cells through small molecule-regulated antibodies.
Nat Commun, 12, 2021
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6UY3
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5D1X
 | | IsdB NEAT2 bound by D4-30 | | 分子名称: | D4-30 Heavy Chain, D4-30 Light Chain, Iron-regulated surface determinant protein B, ... | | 著者 | Deng, X. | | 登録日 | 2015-08-04 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire.
Nat Commun, 7, 2016
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5D1Q
 | | IsdB NEAT2 bound by clone D2-06 | | 分子名称: | D2-06 Heavy Chain, D2-06 Light Chain, Iron-regulated surface determinant protein B, ... | | 著者 | Deng, X. | | 登録日 | 2015-08-04 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire.
Nat Commun, 7, 2016
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5D1Z
 | | IsdB NEAT1 bound by clone D4-10 | | 分子名称: | D4-10 Heavy Chain, D4-10 Light Chain, Iron-regulated surface determinant protein B, ... | | 著者 | Deng, X. | | 登録日 | 2015-08-04 | | 公開日 | 2016-09-14 | | 最終更新日 | 2016-12-07 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire.
Nat Commun, 7, 2016
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6MHR
 | | Structure of the human 4-1BB / Urelumab Fab complex | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, MALONATE ION, ... | | 著者 | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | | 登録日 | 2018-09-18 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab.
Nat Commun, 9, 2018
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6MI2
 | | Structure of the human 4-1BB / Utomilumab Fab complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... | | 著者 | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | | 登録日 | 2018-09-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab.
Nat Commun, 9, 2018
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6MGE
 | | Structure of human 4-1BBL | | 分子名称: | GLYCEROL, PHOSPHATE ION, Tumor necrosis factor ligand superfamily member 9 | | 著者 | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | | 登録日 | 2018-09-13 | | 公開日 | 2018-11-21 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab.
Nat Commun, 9, 2018
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6MGP
 | | Structure of human 4-1BB / 4-1BBL complex | | 分子名称: | ACETATE ION, GLYCEROL, Tumor necrosis factor ligand superfamily member 9, ... | | 著者 | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | | 登録日 | 2018-09-14 | | 公開日 | 2018-11-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab
Nat Commun, 9, 2018
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