8R8O
 
 | | Hallucinated de novo TIM barrel with three helical extensions - HalluTIM3-1 | | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Beck, J, Shanmugaratnam, S, Hocker, B. | | 登録日 | 2023-11-29 | | 公開日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Diversifying de novo TIM barrels by hallucination.
Protein Sci., 33, 2024
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8R8N
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1W9Q
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEFAF peptide | | 分子名称: | BENZOIC ACID, SYNTENIN 1, TNEFAF PEPTIDE | | 著者 | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, Z.S. | | 登録日 | 2004-10-15 | | 公開日 | 2006-03-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
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1W9E
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEFYF peptide | | 分子名称: | BENZOIC ACID, SYNTENIN 1, TNEFYF PEPTIDE | | 著者 | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2004-10-09 | | 公開日 | 2006-03-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
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1W9O
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEYYV peptide | | 分子名称: | BENZOIC ACID, SYNTENIN 1, TNEYYV PEPTIDE | | 著者 | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2004-10-15 | | 公開日 | 2006-03-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
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1V1T
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEYKV peptide | | 分子名称: | BENZOIC ACID, SYNTENIN 1, TNEYKV PEPTIDE | | 著者 | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | 登録日 | 2004-04-23 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
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1YBO
 | | Crystal structure of the PDZ tandem of human syntenin with syndecan peptide | | 分子名称: | Syndecan-4, Syntenin 1 | | 著者 | Grembecka, J, Cooper, D.R, Cierpicki, T, Kang, B.S, Devedjiev, Y, Derewenda, Z. | | 登録日 | 2004-12-21 | | 公開日 | 2006-01-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The binding of the PDZ tandem of syntenin to target proteins
Biochemistry, 45, 2006
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6RUH
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6RVE
 | | Co-substituted beta-Keggin bound to Proteinase K solved by MR | | 分子名称: | Co-substituted beta-Keggin, Proteinase K, SULFATE ION, ... | | 著者 | Breibeck, J, Bijelic, A, Rompel, A. | | 登録日 | 2019-05-31 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Transition metal-substituted Keggin polyoxotungstates enabling covalent attachment to proteinase K upon co-crystallization.
Chem.Commun.(Camb.), 55, 2019
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6RVG
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6RUK
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6RUW
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6RUG
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6RUN
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7A9K
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7A9F
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7A9M
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3LZJ
 | | RB69 DNA Polymerase (Y567A) ternary complex with dCTP Opposite 7,8-Dihydro-8-oxoguanine | | 分子名称: | CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | | 著者 | Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. | | 登録日 | 2010-03-01 | | 公開日 | 2010-05-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .
Biochemistry, 49, 2010
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3LZI
 | | RB69 DNA Polymerase (Y567A) ternary complex with dATP Opposite 7,8-dihydro-8-oxoguanine | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | | 著者 | Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. | | 登録日 | 2010-03-01 | | 公開日 | 2010-05-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .
Biochemistry, 49, 2010
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3NAE
 | | RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | | 著者 | Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. | | 登録日 | 2010-06-01 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | | 主引用文献 | Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin .
Biochemistry, 49, 2010
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5FZP
 | | Structure of the dispase autolysis inducing protein from Streptomyces mobaraensis | | 分子名称: | CALCIUM ION, DISPASE AUTOLYSIS-INDUCING PROTEIN, GLYCEROL | | 著者 | Schmelz, S, Fiebig, D, Beck, J, Fuchsbauer, H.L, Scrima, A. | | 登録日 | 2016-03-15 | | 公開日 | 2016-08-10 | | 最終更新日 | 2016-10-05 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of the Dispase Autolysis Inducing Protein from Streptomyces Mobaraensis and Glutamine Cross-Linking Sites for Transglutaminase
J.Biol.Chem., 291, 2016
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4X5Y
 | | Menin in complex with MI-503 | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-methyl-1-(1H-pyrazol-4-ylmethyl)-5-[(4-{[6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino}piperidin-1-yl)methyl]-1H-indole-2-carbonitrile, ... | | 著者 | Pollock, J, Borkin, D, Cierpicki, T, Grembecka, J. | | 登録日 | 2014-12-06 | | 公開日 | 2015-04-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo.
Cancer Cell, 27, 2015
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4WH7
 | | Structure of the CDC25B Phosphatase Catalytic Domain with Bound Ligand | | 分子名称: | 2-fluoro-4-hydroxybenzonitrile, GLYCEROL, M-phase inducer phosphatase 2, ... | | 著者 | Lund, G.L, Dudkin, S, Borkin, D, Ni, W, Grembecka, J, Cierpicki, T. | | 登録日 | 2014-09-20 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Inhibition of CDC25B Phosphatase Through Disruption of Protein-Protein Interaction.
Acs Chem.Biol., 10, 2015
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4WH9
 | | Structure of the CDC25B Phosphatase Catalytic Domain with Bound Inhibitor | | 分子名称: | 2-[(2-cyano-3-fluoro-5-hydroxyphenyl)sulfanyl]ethanesulfonic acid, GLYCEROL, M-phase inducer phosphatase 2, ... | | 著者 | Lund, G.L, Dudkin, S, Borkin, D, Ni, W, Grembecka, J, Cierpicki, T. | | 登録日 | 2014-09-20 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Inhibition of CDC25B Phosphatase Through Disruption of Protein-Protein Interaction.
Acs Chem.Biol., 10, 2015
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6OPJ
 | | Menin in complex with peptide inhibitor 25 | | 分子名称: | DIMETHYL SULFOXIDE, Menin, Peptide inhibitor 25, ... | | 著者 | Linhares, B.M, Fortuna, P, Cierpicki, T, Grembecka, J, Berlicki, L. | | 登録日 | 2019-04-25 | | 公開日 | 2020-09-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.5006572 Å) | | 主引用文献 | Covalent and noncovalent constraints yield a figure eight-like conformation of a peptide inhibiting the menin-MLL interaction.
Eur.J.Med.Chem., 207, 2020
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