2N9Z
 
 | | Solution structure of K1 lobe of double-knot toxin | | 分子名称: | Tau-theraphotoxin-Hs1a | | 著者 | Bae, C, Anselmi, C, Kalia, J, Jara-Oseguera, A, Schwieters, C.D, Krepkiy, D, Lee, C.W, Kim, E.H, Kim, J.I, Faraldo-Gomez, J.D, Swartz, K.J. | | 登録日 | 2015-12-16 | | 公開日 | 2016-03-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin
Elife, 5, 2016
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2NAJ
 | | Solution structure of K2 lobe of double-knot toxin | | 分子名称: | Tau-theraphotoxin-Hs1a | | 著者 | Bae, C, Anselmi, C, Kalia, J, Jara-Oseguera, A, Schwieters, C.D, Krepkiy, D, Lee, C.W, Kim, E.H, Kim, J.I, Faraldo-Gomez, J.D, Swartz, K.J. | | 登録日 | 2016-01-04 | | 公開日 | 2016-03-02 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin
Elife, 5, 2016
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6EBM
 | | The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, transmembrane domain of subunit alpha | | 分子名称: | Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera | | 著者 | Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J. | | 登録日 | 2018-08-06 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
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6EBK
 | | The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, Voltage-gated potassium channel subunit beta-2 | | 著者 | Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J. | | 登録日 | 2018-08-06 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
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6EBL
 | | The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, cytosolic domain | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera, Voltage-gated potassium channel subunit beta-2 | | 著者 | Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J. | | 登録日 | 2018-08-06 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.
Elife, 7, 2018
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7SJ1
 | | Structure of shaker-W434F | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker | | 著者 | Tan, X, Bae, C, Stix, R, Fernandez, A.I, Huffer, K, Chang, T, Jiang, J, Faraldo-Gomez, J.D, Swartz, K.J. | | 登録日 | 2021-10-15 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of the Shaker Kv channel and mechanism of slow C-type inactivation.
Sci Adv, 8, 2022
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7SIP
 | | Structure of shaker-IR | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker | | 著者 | Tan, X, Bae, C, Stix, R, Fernandez, A.I, Huffer, K, Chang, T, Jiang, J, Faraldo-Gomez, J.D, Swartz, K.J. | | 登録日 | 2021-10-14 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of the Shaker Kv channel and mechanism of slow C-type inactivation.
Sci Adv, 8, 2022
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5N61
 | | RNA polymerase I initially transcribing complex | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | | 登録日 | 2017-02-14 | | 公開日 | 2017-04-05 | | 最終更新日 | 2019-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
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5N5Y
 | | Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation III) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | | 登録日 | 2017-02-14 | | 公開日 | 2017-04-05 | | 最終更新日 | 2018-10-03 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
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5N5Z
 | | Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation II) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | | 登録日 | 2017-02-14 | | 公開日 | 2017-04-05 | | 最終更新日 | 2018-10-03 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
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5N60
 | | Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation I) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | | 登録日 | 2017-02-14 | | 公開日 | 2017-04-05 | | 最終更新日 | 2018-10-03 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
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5O7X
 | | CRYSTAL STRUCTURE OF S. CEREVISIAE CORE FACTOR AT 3.2A RESOLUTION | | 分子名称: | MAGNESIUM ION, RNA polymerase I-specific transcription initiation factor RRN11, RNA polymerase I-specific transcription initiation factor RRN6, ... | | 著者 | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | | 登録日 | 2017-06-09 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
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2BG5
 | | Crystal Structure of the Phosphoenolpyruvate-binding Enzyme I-Domain from the Thermoanaerobacter tengcongensis PEP: Sugar Phosphotransferase System (PTS) | | 分子名称: | PHOSPHOENOLPYRUVATE-PROTEIN KINASE | | 著者 | Oberholzer, A.E, Bumann, M, Schneider, P, Baechler, C, Siebold, C, Baumann, U, Erni, B. | | 登録日 | 2004-12-17 | | 公開日 | 2005-02-02 | | 最終更新日 | 2018-03-07 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal Structure of the Phosphoenolpyruvate-Binding Enzyme I-Domain from the Thermoanaerobacter Tengcongensis Pep: Sugar Phosphotransferase System (Pts)
J.Mol.Biol., 346, 2005
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2F95
 | | M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure | | 分子名称: | RETINAL, Sensory rhodopsin II, Sensory rhodopsin II transducer, ... | | 著者 | Moukhametzianov, R.I, Klare, J.P, Efremov, R.G, Baecken, C, Goeppner, A, Labahn, J, Engelhard, M, Bueldt, G, Gordeliy, V.I. | | 登録日 | 2005-12-05 | | 公開日 | 2006-03-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Development of the signal in sensory rhodopsin and its transfer to the cognate transducer.
Nature, 440, 2006
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2F93
 | | K Intermediate Structure of Sensory Rhodopsin II/Transducer Complex in Combination with the Ground State Structure | | 分子名称: | RETINAL, Sensory rhodopsin II, Sensory rhodopsin II transducer, ... | | 著者 | Moukhametzianov, R.I, Klare, J.P, Efremov, R.G, Baecken, C, Goeppner, A, Labahn, J, Engelhard, M, Bueldt, G, Gordeliy, V.I. | | 登録日 | 2005-12-05 | | 公開日 | 2006-03-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Development of the signal in sensory rhodopsin and its transfer to the cognate transducer.
Nature, 440, 2006
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8TEO
 | | Shaker in low K+ (4mM K+) | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker | | 著者 | Tan, X, Swartz, K.J. | | 登録日 | 2023-07-06 | | 公開日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (2.39 Å) | | 主引用文献 | Eukaryotic Kv channel Shaker inactivates through selectivity filter dilation rather than collapse.
Sci Adv, 9, 2023
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8SD3
 | | CryoEM structure of rat Kv2.1(1-598) wild type in nanodiscs | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel subfamily B member 1 | | 著者 | Tan, X, Swartz, K.J. | | 登録日 | 2023-04-06 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Inactivation of the Kv2.1 channel through electromechanical coupling.
Nature, 622, 2023
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8SDA
 | | CryoEM structure of rat Kv2.1(1-598) L403A mutant in nanodiscs | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel subfamily B member 1 | | 著者 | Tan, X, Swartz, K.J. | | 登録日 | 2023-04-06 | | 公開日 | 2023-09-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Inactivation of the Kv2.1 channel through electromechanical coupling.
Nature, 622, 2023
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8SLX
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8SLY
 | | Rat TRPV2 bound with 2 CBD ligands in nanodiscs | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Transient receptor potential cation channel subfamily V member 2, ... | | 著者 | Tan, X, Swartz, K.J. | | 登録日 | 2023-04-24 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Cannabidiol sensitizes TRPV2 channels to activation by 2-APB.
Elife, 12, 2023
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7AHK
 | | Crystal structure of the outward-facing state of the substrate-free Na+-only bound glutamate transporter homolog GltPh | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, EICOSANE, GLYCEROL, ... | | 著者 | Kovalev, K, Alleva, C, Astashkin, A, Machtens, J.-P, Fahlke, C, Gordeliy, V. | | 登録日 | 2020-09-24 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Na + -dependent gate dynamics and electrostatic attraction ensure substrate coupling in glutamate transporters.
Sci Adv, 6, 2020
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2LYG
 | | Fuc_TBA | | 分子名称: | 2-hydroxyethyl 6-deoxy-beta-L-galactopyranoside, DNA (5'-D(P*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3') | | 著者 | Gomez-Pinto, I, Vengut-Climent, E, Lucas, R, Avio, A, Eritja, R, Gonzalez-Ibaez, C, Morales, J. | | 登録日 | 2012-09-18 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Carbohydrate-DNA interactions at G-quadruplexes: folding and stability changes by attaching sugars at the 5'-end.
Chemistry, 19, 2013
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7U63
 | | Crystal Structure Anti-Oxycodone Antibody HY2-A12 Fab Complexed with Oxycodone | | 分子名称: | 14-hydroxy-3-methoxy-17-methyl-5beta-4,5-epoxymorphinan-6-one, HY2-A12 Fab Heavy Chain, HY2-A12 Fab Light Chain | | 著者 | Rodarte, J.V, Pancera, M.P, Weidle, C, Rupert, P.B, Strong, R.K. | | 登録日 | 2022-03-03 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
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6SQG
 | | Crystal structure of viral rhodopsin OLPVRII | | 分子名称: | (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, EICOSANE, RETINAL, ... | | 著者 | Gushchin, I, Kovalev, K, Bratanov, D, Polovinkin, V, Astashkin, R, Popov, A, Bourenkov, G, Gordeliy, V. | | 登録日 | 2019-09-03 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Unique structure and function of viral rhodopsins.
Nat Commun, 10, 2019
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7U62
 | | Crystal structure of Anti-Heroin Antibody HY4-1F9 Fab Complexed with Morphine | | 分子名称: | (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, ACETATE ION, HY4-1F9 Fab Heavy Chain, ... | | 著者 | Rodarte, J.V, Pancera, M.P. | | 登録日 | 2022-03-03 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
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