2NAJ

Solution structure of K2 lobe of double-knot toxin

Summary for 2NAJ

• Entry DOI: 10.2210/pdb2naj/pdb
• NMR Information: BMRB: 25939
• Descriptor: Tau-theraphotoxin-Hs1a (1 entity in total)
• Functional Keywords: trpv1, toxins, tarantula, spider, ick, double-knot toxin, dktx, k2, toxin
• Biological source: Haplopelma schmidti (Chinese earth tiger)
• Cellular location: Secreted: P0CH43
• Total number of polymer chains: 1
• Total formula weight: 3686.29

Authors

Bae, C.,Anselmi, C.,Kalia, J.,Jara-Oseguera, A.,Schwieters, C.D.,Krepkiy, D.,Lee, C.W.,Kim, E.H.,Kim, J.I.,Faraldo-Gomez, J.D.,Swartz, K.J. (deposition date: 2016-01-04, release date: 2016-03-02, Last modification date: 2023-06-14)

• Primary citation: Bae, C.,Anselmi, C.,Kalia, J.,Jara-Oseguera, A.,Schwieters, C.D.,Krepkiy, D.,Lee, C.W.,Kim, E.H.,Kim, J.I.,Faraldo-Gomez, J.D.,Swartz, K.J.; Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin; Elife, 5:-, 2016; PubMed: 26880553; DOI: 10.7554/eLife.11273

Experimental method

SOLUTION NMR