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2VLC
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BU of 2vlc by Molmil
Crystal structure of Natural Cinnamomin (Isoform III)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ribosome-inactivating protein, beta-D-mannopyranose, ...
著者Azzi, A, Wang, T, Zhu, D.-W, Zou, Y.-S, Liu, W.-Y, Lin, S.-X.
登録日2008-01-11
公開日2009-02-10
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal Structure of Native Cinnamomin Isoform III and its Comparison with Other Ribosome Inactivating Proteins.
Proteins: Struct., Funct., Bioinf., 74, 2009
1IOL
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BU of 1iol by Molmil
ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE COMPLEXED 17-BETA-ESTRADIOL
分子名称: ESTRADIOL, ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE
著者Azzi, A, Rehse, P.H, Zhu, D.-W, Campbell, R.L, Labrie, F, Lin, S.-X.
登録日1996-06-20
公開日1997-07-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase complexed with 17 beta-estradiol.
Nat.Struct.Biol., 3, 1996
1RL9
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BU of 1rl9 by Molmil
Crystal structure of Creatine-ADP arginine kinase ternary complex
分子名称: (DIAMINOMETHYL-METHYL-AMINO)-ACETIC ACID, ADENOSINE-5'-DIPHOSPHATE, Arginine kinase, ...
著者Azzi, A, Clark, S.A, Ellington, R.W, Chapman, M.S.
登録日2003-11-25
公開日2004-05-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The role of phosphagen specificity loops in arginine kinase.
Protein Sci., 13, 2004
2L4L
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BU of 2l4l by Molmil
Structural insights into the cTAR DNA recognition by the HIV-1 Nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NC
分子名称: 5'-D(*CP*TP*GP*G)-3', HIV-1 nucleocapsid protein NCp7, ZINC ION
著者Bazzi, A, Zargarian, L, Chaminade, F, Boudier, C, De Rocquigny, H, Rene, B, Mely, Y, Fosse, P, Mauffret, O.
登録日2010-10-08
公開日2010-12-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural insights into the cTAR DNA recognition by the HIV-1 nucleocapsid protein: role of sugar deoxyriboses in the binding polarity of NC.
Nucleic Acids Res., 39, 2011
2FGB
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BU of 2fgb by Molmil
Crystal structure of human 17bet a-hydroxysteroid dehydrogenase type 5 in complexes with PEG and NADP
分子名称: ACETATE ION, Aldo-keto reductase family 1 member C3, HEXAETHYLENE GLYCOL, ...
著者Qiu, W, Zhou, M, Azzi, A, Luu-The, V, Labrie, F, Lin, S.X.
登録日2005-12-21
公開日2006-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.
J.Biol.Chem., 282, 2007
1LP3
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BU of 1lp3 by Molmil
The Atomic Structure of Adeno-Associated Virus (AAV-2), a Vector for Human Gene Therapy
分子名称: AAV-2 capsid protein
著者Xie, Q, Bu, W, Bhatia, S, Hare, J, Somasundaram, T, Azzi, A, Chapman, M.S.
登録日2002-05-07
公開日2002-08-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.
Proc.Natl.Acad.Sci.USA, 99, 2002
1P52
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BU of 1p52 by Molmil
Structure of Arginine kinase E314D mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, Arginine kinase, D-ARGININE, ...
著者Pruett, P.S, Azzi, A, Clark, S.A, Yousef, M.S, Gattis, J.L, Somasundarum, T, Ellington, W.R, Chapman, M.S.
登録日2003-04-24
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The putative catalytic bases have, at most, an accessory role in the mechanism of arginine kinase.
J.Biol.Chem., 278, 2003
1P50
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BU of 1p50 by Molmil
Transition state structure of an Arginine Kinase mutant
分子名称: ADENOSINE-5'-DIPHOSPHATE, ARGININE, Arginine kinase, ...
著者Pruett, P.S, Azzi, A, Clark, S.A, Yousef, M.S, Gattis, J.L, Somasundarum, T, Ellington, W.R, Chapman, M.S.
登録日2003-04-24
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The putative catalytic bases have, at most, an accessory role in the mechanism of arginine kinase.
J.Biol.Chem., 278, 2003
7O2R
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BU of 7o2r by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with ITF3985
分子名称: 3,5-bis(fluoranyl)-~{N}-oxidanyl-4-[(5-pyrimidin-2-yl-1,2,3,4-tetrazol-2-yl)methyl]benzamide, DI(HYDROXYETHYL)ETHER, Histone deacetylase 6, ...
著者Zrubek, K, Sandrone, G, Cukier, C.D, Stevenazzi, A.
登録日2021-03-31
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Role of Fluorination in the Histone Deacetylase 6 (HDAC6) Selectivity of Benzohydroxamate-Based Inhibitors.
Acs Med.Chem.Lett., 12, 2021
7O2P
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BU of 7o2p by Molmil
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with ITF3756
分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Zrubek, K, Sandrone, G, Cukier, C.D, Stevenazzi, A.
登録日2021-03-31
公開日2021-10-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Role of Fluorination in the Histone Deacetylase 6 (HDAC6) Selectivity of Benzohydroxamate-Based Inhibitors.
Acs Med.Chem.Lett., 12, 2021
8A8Z
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BU of 8a8z by Molmil
Crystal structure of Danio rerio HDAC6 CD2 in complex with in situ enzymatically hydrolyzed DFMO-based ITF5924
分子名称: 4-[[4-[4-(imidazolidin-2-ylideneamino)phenyl]-1,2,3-triazol-1-yl]methyl]benzohydrazide, Histone deacetylase 6, POTASSIUM ION, ...
著者Zrubek, K, Sandrone, G, Cukier, C.D, Stevenazzi, A.
登録日2022-06-27
公開日2023-01-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Difluoromethyl-1,3,4-oxadiazoles are slow-binding substrate analog inhibitors of histone deacetylase 6 with unprecedented isotype selectivity.
J.Biol.Chem., 299, 2022
1ZQ5
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BU of 1zq5 by Molmil
Crystal structure of human androgenic 17beta-hydroxysteroid dehydrogenase type 5 in complexed with a potent inhibitor EM1404
分子名称: 3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN, ACETATE ION, Aldo-keto reductase family 1 member C3, ...
著者Qiu, W, Zhou, M, Ghanmi, D, Luu-The, V, Labrie, F, Lin, S.X.
登録日2005-05-18
公開日2006-12-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure-based inhibitor design for an enzyme that binds different steroids: a potent inhibitor for human type 5 17beta-hydroxysteroid dehydrogenase.
J.Biol.Chem., 282, 2007
6ZVF
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BU of 6zvf by Molmil
Crystal structure of the recombinant Fab fragment derived from the hybridoma M3/38 in complex with a human Galectin-3 peptide
分子名称: Chimeric Fab M3/38 (L,H), Galectin-3
著者Skerra, A, Eichinger, A.
登録日2020-07-24
公開日2021-04-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Effective rational humanization of a PASylated anti-galectin-3 Fab for the sensitive PET imaging of thyroid cancer in vivo.
Sci Rep, 11, 2021
2WUT
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BU of 2wut by Molmil
Crystal structure of human myelin protein P2 in complex with palmitate
分子名称: CHLORIDE ION, GLYCEROL, MYELIN P2 PROTEIN, ...
著者Majava, V, Nanekar, R, Kursula, P.
登録日2009-10-09
公開日2010-05-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Functional Characterization of Human Peripheral Nervous System Myelin Protein P2.
Plos One, 5, 2010

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