2OO4
 
 | | Structure of LNR-HD (Negative Regulatory Region) from human Notch 2 | | 分子名称: | CALCIUM ION, GLYCEROL, Neurogenic locus notch homolog protein 2, ... | | 著者 | Gordon, W.R, Vardar-Ulu, D, Histen, G, Sanchez-Irizarry, C, Aster, J.C, Blacklow, S.C. | | 登録日 | 2007-01-25 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | | 主引用文献 | Structural basis for autoinhibition of Notch
Nat.Struct.Mol.Biol., 14, 2007
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1PB5
 | | NMR Structure of a Prototype LNR Module from Human Notch1 | | 分子名称: | CALCIUM ION, Neurogenic locus notch homolog protein 1 | | 著者 | Vardar, D, North, C.L, Sanchez-Irizarry, C, Aster, J.C, Blacklow, S.C. | | 登録日 | 2003-05-14 | | 公開日 | 2003-06-17 | | 最終更新日 | 2024-10-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Nuclear Magnetic Resonance Structure of a Prototype Lin12-Notch Repeat Module from Human Notch1
Biochemistry, 42, 2003
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3NBN
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8V0E
 | | ANK repeat of MIB1 | | 分子名称: | E3 ubiquitin-protein ligase MIB1, Unidentified MIB1 peptide | | 著者 | Cao, R, Blacklow, S.C. | | 登録日 | 2023-11-17 | | 公開日 | 2024-09-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structural requirements for activity of Mind bomb1 in Notch signaling.
Structure, 32, 2024
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6PY8
 | | Crystal structure of the RBPJ-NOTCH1-NRARP ternary complex bound to DNA | | 分子名称: | DNA, Neurogenic locus notch homolog protein 1, Notch-regulated ankyrin repeat-containing protein, ... | | 著者 | Jarrett, S.M, Seegar, T.C.M, Blacklow, S.C. | | 登録日 | 2019-07-29 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | | 主引用文献 | Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling.
Sci.Signal., 12, 2019
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4ZLP
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3I08
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2F8Y
 | | Crystal structure of human Notch1 ankyrin repeats to 1.55A resolution. | | 分子名称: | Notch homolog 1, translocation-associated (Drosophila), SULFATE ION | | 著者 | Nam, Y, Sliz, P, Blacklow, S.C. | | 登録日 | 2005-12-04 | | 公開日 | 2006-04-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
Cell(Cambridge,Mass.), 124, 2006
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2F8X
 | | Crystal structure of activated Notch, CSL and MAML on HES-1 promoter DNA sequence | | 分子名称: | 5'-D(*GP*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*AP*AP*A)-3', 5'-D(*TP*TP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*TP*AP*AP*C)-3', Mastermind-like protein 1, ... | | 著者 | Nam, Y, Sliz, P, Blacklow, S.C. | | 登録日 | 2005-12-04 | | 公開日 | 2006-04-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
Cell(Cambridge,Mass.), 124, 2006
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5CZX
 | | Crystal structure of Notch3 NRR in complex with 20358 Fab | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 20358 Fab heavy chain, ... | | 著者 | Hu, T, Fryer, C, Chopra, R, Clark, K. | | 登録日 | 2015-08-01 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Oncogene, 35, 2016
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5CZV
 | | Crystal structure of Notch3 NRR in complex with 20350 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fab 20350 heavy chain, ... | | 著者 | Hu, T, Fryer, C, Chopra, R, Clark, K. | | 登録日 | 2015-08-01 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
Oncogene, 35, 2016
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3ETO
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