1AWJ
 
 | | INTRAMOLECULAR ITK-PROLINE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE | | 分子名称: | ITK | | 著者 | Andreotti, A.H, Bunnell, S.C, Feng, S, Berg, L.J, Schreiber, S.L. | | 登録日 | 1997-10-02 | | 公開日 | 1998-01-14 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Regulatory intramolecular association in a tyrosine kinase of the Tec family.
Nature, 385, 1997
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2K79
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2K7A
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3S9K
 | | Crystal structure of the Itk SH2 domain. | | 分子名称: | CITRIC ACID, Tyrosine-protein kinase ITK/TSK | | 著者 | Joseph, R.E, Ginder, N.D, Hoy, J.A, Nix, J.C, Fulton, B.D, Honzatko, R.B, Andreotti, A.H. | | 登録日 | 2011-06-01 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.354 Å) | | 主引用文献 | Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures.
Acta Crystallogr.,Sect.F, 68, 2012
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2ETZ
 | | The NMR minimized average structure of the Itk SH2 domain bound to a phosphopeptide | | 分子名称: | Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK | | 著者 | Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. | | 登録日 | 2005-10-27 | | 公開日 | 2006-02-07 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide.
J.Mol.Biol., 357, 2006
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2EU0
 | | The NMR ensemble structure of the Itk SH2 domain bound to a phosphopeptide | | 分子名称: | Lymphocyte cytosolic protein 2 phosphopeptide fragment, Tyrosine-protein kinase ITK/TSK | | 著者 | Sundd, M, Pletneva, E.V, Fulton, D.B, Andreotti, A.H. | | 登録日 | 2005-10-27 | | 公開日 | 2006-02-07 | | 最終更新日 | 2022-03-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular Details of Itk Activation by Prolyl Isomerization and Phospholigand Binding: The NMR Structure of the Itk SH2 Domain Bound to a Phosphopeptide.
J.Mol.Biol., 357, 2006
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8GMB
 | | Crystal structure of the full-length Bruton's tyrosine kinase (PH-TH domain not visible) | | 分子名称: | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, Tyrosine-protein kinase BTK | | 著者 | Lin, D.Y, Andreotti, A.H. | | 登録日 | 2023-03-24 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states.
Elife, 12, 2024
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8FF0
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8FD9
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8S9F
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8S93
 | | Crystal structure of the PH-TH/kinase complex of Bruton's tyrosine kinase | | 分子名称: | 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, GLYCEROL, Tyrosine-protein kinase BTK, ... | | 著者 | Lin, D.Y, Andreotti, A.H. | | 登録日 | 2023-03-27 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states.
Elife, 12, 2024
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2LMJ
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1LUK
 | | NMR Structure of the Itk SH2 domain, Pro287cis, Energy minimized average structure | | 分子名称: | Tyrosine-protein kinase ITK/TSK | | 著者 | Mallis, R.J, Brazin, K.N, Fulton, B.F, Andreotti, A.H. | | 登録日 | 2002-05-22 | | 公開日 | 2002-11-27 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural characterization of a proline-driven conformational switch
within the Itk SH2 domain
Nat.Struct.Biol., 9, 2002
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1LUN
 | | NMR Structure of the Itk SH2 domain, Pro287trans, energy minimized average structure | | 分子名称: | Tyrosine-protein kinase ITK/TSK | | 著者 | Mallis, R.J, Brazin, K.N, Fulton, D.B, Andreotti, A.H. | | 登録日 | 2002-05-22 | | 公開日 | 2002-11-27 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural characterization of a proline-driven conformational switch
within the Itk SH2 domain
Nat.Struct.Biol., 9, 2002
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1MA4
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1MA6
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1LUM
 | | NMR Structure of the Itk SH2 domain, Pro287trans, 20 low energy structures | | 分子名称: | Tyrosine-protein kinase ITK/TSK | | 著者 | Mallis, R.J, Brazin, K.N, Fulton, D.B, Andreotti, A.H. | | 登録日 | 2002-05-22 | | 公開日 | 2002-11-27 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural characterization of a proline-driven conformational switch
within the Itk SH2 domain
Nat.Struct.Biol., 9, 2002
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1MA5
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1MA2
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1YX7
 | | NMR structure of Calsensin, energy minimized average structure. | | 分子名称: | Calsensin | | 著者 | Venkitaramani, D.V, Fulton, D.B, Andreotti, A.H, Johansen, K.M, Johansen, J. | | 登録日 | 2005-02-19 | | 公開日 | 2005-04-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and backbone dynamics of Calsensin, an invertebrate neuronal calcium-binding protein.
Protein Sci., 14, 2005
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1YX8
 | | NMR structure of Calsensin, 20 low energy structures. | | 分子名称: | Calsensin | | 著者 | Venkitaramani, D.V, Fulton, D.B, Andreotti, A.H, Johansen, K.M, Johansen, J. | | 登録日 | 2005-02-19 | | 公開日 | 2005-04-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and backbone dynamics of Calsensin, an invertebrate neuronal calcium-binding protein.
Protein Sci., 14, 2005
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2RNA
 | | Itk SH3 average minimized | | 分子名称: | Tyrosine-protein kinase ITK/TSK | | 著者 | Severin, A.J. | | 登録日 | 2007-12-08 | | 公開日 | 2007-12-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure note: murine Itk SH3 domain
To be Published
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1LUI
 | | NMR Structures of Itk SH2 domain, Pro287cis isoform, ensemble of 20 low energy structures | | 分子名称: | Tyrosine-protein kinase ITK/TSK | | 著者 | Mallis, R.J, Brazin, K.N, Fulton, B.F, Andreotti, A.M. | | 登録日 | 2002-05-22 | | 公開日 | 2002-11-27 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural characterization of a proline-driven conformational switch
within the Itk SH2 domain
Nat.Struct.Biol., 9, 2002
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2RN8
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