4ICG
 
 | | N-terminal dimerization domain of H-NS in complex with Hha (Salmonella Typhimurium) | | 分子名称: | DNA-binding protein H-NS, Hemolysin expression modulating protein (Involved in environmental regulation of virulence factors) | | 著者 | Ali, S.S, Whitney, J.C, Stevenson, J, Robinson, H, Howell, P.L, Navarre, W.W. | | 登録日 | 2012-12-10 | | 公開日 | 2013-03-27 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.9217 Å) | | 主引用文献 | Structural Insights into the Regulation of Foreign Genes in Salmonella by the Hha/H-NS Complex.
J.Biol.Chem., 288, 2013
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8UZ1
 | | Straight actin filament from Arp2/3 branch junction sample (ADP-BeFx) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | | 登録日 | 2023-11-14 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
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8UXW
 | | Arp2/3 branch junction complex, ADP state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | | 登録日 | 2023-11-11 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
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8UXX
 | | Arp2/3 branch junction complex, BeFx state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | | 著者 | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | | 登録日 | 2023-11-11 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
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8UZ0
 | | Straight actin filament from Arp2/3 branch junction sample (ADP) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | | 登録日 | 2023-11-14 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex.
Nat Commun, 15, 2024
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6XH1
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6XH0
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6XH3
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6XH2
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4KWV
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4KWW
 | | The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid | | 分子名称: | Nicotinate-nucleotide pyrophosphorylase [carboxylating], PHTHALIC ACID | | 著者 | Malik, S.S, Dimeka, P.N, Ncube, Z, Toth, E.A. | | 登録日 | 2013-05-24 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid.
Proteins, 82, 2014
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4XEG
 | | Structure of the enzyme-product complex resulting from TDG action on a G/hmU mismatch | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2014-12-23 | | 公開日 | 2015-09-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
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4Z47
 | | Structure of the enzyme-product complex resulting from TDG action on a GU mismatch in the presence of excess base | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA, ... | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2015-04-01 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
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4Z7Z
 | | Structure of the enzyme-product complex resulting from TDG action on a GT mismatch in the presence of excess base | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2015-04-08 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
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4Z7B
 | | Structure of the enzyme-product complex resulting from TDG action on a GfC mismatch | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2015-04-07 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
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4Z3A
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5CYS
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5JXY
 | | Enzyme-substrate complex of TDG catalytic domain bound to a G/U analog | | 分子名称: | DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | | 著者 | Pidugu, L.S, Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2016-05-13 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016
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5FF8
 | | TDG enzyme-product complex | | 分子名称: | DNA, G/T mismatch-specific thymine DNA glycosylase | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2015-12-18 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016
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5HF7
 | | TDG enzyme-substrate complex | | 分子名称: | DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2016-01-06 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016
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7KJR
 | | Cryo-EM structure of SARS-CoV-2 ORF3a | | 分子名称: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Apolipoprotein A-I, ORF3a protein | | 著者 | Kern, D.M, Hoel, C.M, Kotecha, A, Brohawn, S.G. | | 登録日 | 2020-10-26 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.08 Å) | | 主引用文献 | Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs.
Nat.Struct.Mol.Biol., 28, 2021
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6XDC
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6U15
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6U16
 | | Human thymine DNA glycosylase N140A mutant bound to DNA with 5-carboxyl-dC substrate | | 分子名称: | 1,2-ETHANEDIOL, DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | | 著者 | Pidugu, L.S, Pozharski, E, Drohat, A.C. | | 登録日 | 2019-08-15 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase.
J.Am.Chem.Soc., 141, 2019
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6U17
 | | Human thymine DNA glycosylase bound to DNA with 2'-F-5-carboxyl-dC substrate analog | | 分子名称: | ACETATE ION, DNA (28-MER), DNA (30-MER), ... | | 著者 | Pidugu, L.S, Pozharski, E, Drohat, A.C. | | 登録日 | 2019-08-15 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase.
J.Am.Chem.Soc., 141, 2019
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