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6L3H
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Cryo-EM structure of dimeric quinol dependent Nitric Oxide Reductase (qNOR) from the pathogen Neisseria meninigitidis
分子名称: CALCIUM ION, FE (III) ION, Nitric-oxide reductase, ...
著者Jamali, M.M.A, Gopalasingam, C.C, Johnson, R.M, Tosha, T, Muench, S.P, Muramoto, K, Antonyuk, S.V, Shiro, Y, Hasnain, S.S.
登録日2019-10-11
公開日2020-04-01
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献The active form of quinol-dependent nitric oxide reductase fromNeisseria meningitidisis a dimer.
Iucrj, 7, 2020
1DU5
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BU of 1du5 by Molmil
THE CRYSTAL STRUCTURE OF ZEAMATIN.
分子名称: ZEAMATIN
著者Batalia, M.A, Monzingo, A.F, Ernst, S, Roberts, W, Robertus, J.D.
登録日2000-01-14
公開日2000-02-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of the antifungal protein zeamatin, a member of the thaumatin-like, PR-5 protein family.
Nat.Struct.Biol., 3, 1996
6L1X
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BU of 6l1x by Molmil
Quinol-dependent nitric oxide reductase (qNOR) from Neisseria meningitidis in the monomeric oxidized state with zinc complex.
分子名称: CALCIUM ION, FE (III) ION, Nitric-oxide reductase, ...
著者Jamali, M.M.A, Antonyuk, S.V, Tosha, T, Muramoto, K, Hasnain, S.S, Shiro, Y.
登録日2019-10-01
公開日2020-04-01
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献The active form of quinol-dependent nitric oxide reductase fromNeisseria meningitidisis a dimer.
Iucrj, 7, 2020
8TV4
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BU of 8tv4 by Molmil
NMR structure of temporin L in solution
分子名称: Temporin-1Tl peptide
著者McShan, A.C, Jia, R, Halim, M.A.
登録日2023-08-17
公開日2023-09-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Antiviral peptides inhibiting the main protease of SARS-CoV-2 investigated by computational screening and in vitro protease assay.
J.Pept.Sci., 30, 2024
1QR1
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BU of 1qr1 by Molmil
POOR BINDING OF A HER-2/NEU EPITOPE (GP2) TO HLA-A2.1 IS DUE TO A LACK OF INTERACTIONS IN THE CENTER OF THE PEPTIDE
分子名称: BETA-2 MICROGLOBULIN, GP2 PEPTIDE, HLA-A2.1 HEAVY CHAIN
著者Kuhns, J.J, Batalia, M.A, Yan, S, Collins, E.J.
登録日1999-06-17
公開日2000-01-01
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Poor binding of a HER-2/neu epitope (GP2) to HLA-A2.1 is due to a lack of interactions with the center of the peptide.
J.Biol.Chem., 274, 1999
2MBS
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BU of 2mbs by Molmil
NMR solution structure of oxidized KpDsbA
分子名称: Thiol:disulfide interchange protein
著者Kurth, F, Rimmer, K, Premkumar, L, Mohanty, B, Duprez, W, Halili, M.A, Shouldice, S.R, Heras, B, Fairlie, D.P, Scanlon, M.J, Martin, J.L.
登録日2013-08-03
公開日2013-12-11
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes.
Plos One, 8, 2013
6T6V
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BU of 6t6v by Molmil
Glu-494-Ala inactive monomer of a quinol dependent Nitric Oxide Reductase (qNOR) from Alcaligenes xylosoxidans
分子名称: CALCIUM ION, Nitric oxide reductase subunit B, PROTOPORPHYRIN IX CONTAINING FE
著者Gopalasingam, C.C, Johnson, R.M, Antonyuk, S.V, Muench, S.P, Hasnain, S.S.
登録日2019-10-19
公開日2020-04-01
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献The active form of quinol-dependent nitric oxide reductase fromNeisseria meningitidisis a dimer.
Iucrj, 7, 2020
7SFX
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10A1 Fab in complex with CD99 peptide
分子名称: 10A1 Fab heavy chain, 10A1 Fab light chain, CD99 antigen peptide
著者Romero, L.A, Hattori, T, Koide, S.
登録日2021-10-04
公開日2021-12-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献High-valency Anti-CD99 Antibodies Toward the Treatment of T Cell Acute Lymphoblastic Leukemia.
J.Mol.Biol., 434, 2021
6T2E
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BU of 6t2e by Molmil
Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions
分子名称: E3 ubiquitin-protein ligase Mdm2, Stapled peptide GAR300-Gm
著者Groves, R.M, Ali, M.A, Atmaj, J, van Oosterwijk, N, Domling, A, Rivera, G.D, Ricardo, G.M.
登録日2019-10-08
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions.
Angew.Chem.Int.Ed.Engl., 59, 2020
6T2F
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Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions
分子名称: 2-(methylamino)-~{N}-[[3-[[2-(methylamino)ethanoylamino]methyl]phenyl]methyl]ethanamide, E3 ubiquitin-protein ligase Mdm2, MDM2 in complex with GAR300-Am
著者Groves, R.M, Ali, M.A, Atmaj, J, van Oosterwijk, N, Domling, A, Rivera, G.D, Ricardo, G.M.
登録日2019-10-08
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions.
Angew.Chem.Int.Ed.Engl., 59, 2020
6T2D
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BU of 6t2d by Molmil
Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions
分子名称: 2-(methylamino)-~{N}-[[4-[[2-(methylamino)ethanoylamino]methyl]phenyl]methyl]ethanamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ...
著者Groves, R.M, Ali, M.A, Atmaj, J, van Oosterwijk, N, Domling, A, Rivera, G.D, Ricardo, G.M.
登録日2019-10-08
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Multicomponent Peptide Stapling as a Diversity-Driven Tool for the Development of Inhibitors of Protein-Protein Interactions.
Angew.Chem.Int.Ed.Engl., 59, 2020
4P3Y
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BU of 4p3y by Molmil
Crystal structure of Acinetobacter baumannii DsbA in complex with EF-Tu
分子名称: Elongation factor Tu 1, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ...
著者Premkumar, L, Martin, J.L.
登録日2014-03-10
公開日2014-06-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.154 Å)
主引用文献Structure of the Acinetobacter baumannii Dithiol Oxidase DsbA Bound to Elongation Factor EF-Tu Reveals a Novel Protein Interaction Site.
J.Biol.Chem., 289, 2014
1EEZ
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BU of 1eez by Molmil
Crystal Structure Determination of HLA-A2.1 Complexed to GP2 Peptide Variant(I2L/V5L)
分子名称: BETA-2-MICROGLOBULIN (LIGHT CHAIN), GP2 PEPTIDE, HLA-A2.1 MHC CLASS I (HEAVY CHAIN)
著者Sharma, A.K, Kuhns, J.J, Collins, E.J.
登録日2000-02-04
公開日2003-06-10
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Class I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contacts.
J.Biol.Chem., 276, 2001
5ID4
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BU of 5id4 by Molmil
Crystal structure of Proteus mirabilis ScsC in an extended conformation
分子名称: DsbA-like protein
著者Furlong, E.J, Kurth, F, Choudhury, H.G, Martin, J.L.
登録日2016-02-23
公開日2017-07-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.921 Å)
主引用文献Proteus mirabilis ScsC is a highly dynamic, novel trimeric protein disulfide isomerase
Nat Commun, 2017
5IDR
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BU of 5idr by Molmil
Crystal structure of Proteus Mirabilis ScsC in a transitional conformation
分子名称: DsbA-like protein
著者Furlong, E.J, Kurth, F, Choudhury, H.G, Martin, J.L.
登録日2016-02-24
公開日2017-08-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.562 Å)
主引用文献A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.
Nat Commun, 8, 2017
8GB0
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BU of 8gb0 by Molmil
SARS-CoV-2 Spike H655Y variant, One RBD Open
分子名称: Spike glycoprotein
著者Egri, S.B, Shen, K, Luban, J.
登録日2023-02-24
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness.
Biorxiv, 2023
4XVW
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BU of 4xvw by Molmil
Crystal structure of Proteus mirabilis ScsC in a compact conformation
分子名称: DsbA-like protein
著者Kurth, F, Furlong, E.J, Premkumar, L, Martin, J.L.
登録日2015-01-27
公開日2016-06-08
最終更新日2022-02-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance.
Nat Commun, 8, 2017
4TKY
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BU of 4tky by Molmil
The complex structure of E. coli DsbA bound to a peptide at the DsbA/DsbB interface
分子名称: ACETYL GROUP, AMINO GROUP, PRO-PHE-ALA-THR-CYS-ASP-SER, ...
著者Premkumar, L, Martin, J.L.
登録日2014-05-28
公開日2015-01-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Peptide Inhibitors of the Escherichia coli DsbA Oxidative Machinery Essential for Bacterial Virulence.
J.Med.Chem., 58, 2015
6EEZ
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BU of 6eez by Molmil
Crystal Structure of the thiol-disulfide exchange protein alpha-DsbA2 from Wolbachia pipientis
分子名称: DsbA-like disulfide oxidoreductase
著者Walden, P.M, Lakshmanane, P, King, G.J, Martin, J.L.
登録日2018-08-15
公開日2019-04-17
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The atypical thiol-disulfide exchange protein alpha-DsbA2 from Wolbachia pipientis is a homotrimeric disulfide isomerase.
Acta Crystallogr D Struct Biol, 75, 2019
4DVC
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BU of 4dvc by Molmil
Structural and functional studies of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera toxin production
分子名称: DIMETHYL SULFOXIDE, SULFATE ION, Thiol:disulfide interchange protein DsbA
著者Walden, P.M, Martin, J.L.
登録日2012-02-23
公開日2012-10-31
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The 1.2 A resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production
Acta Crystallogr.,Sect.D, 68, 2012
7RGV
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BU of 7rgv by Molmil
Structure of Caulobacter crescentus Suppressor of copper sensitivity protein C
分子名称: Thioredoxin domain-containing protein
著者Petit, G.A, Martin, J.L, Gulbis, J.M.
登録日2021-07-15
公開日2022-03-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric disulfide isomerase that binds copper(I) with subpicomolar affinity.
Acta Crystallogr D Struct Biol, 78, 2022
4MCU
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BU of 4mcu by Molmil
Crystal structure of disulfide oxidoreductase from Klebsiella pneumoniae in reduced state
分子名称: Thiol:disulfide interchange protein
著者Kurth, F, Premkumar, L, Martin, J.L.
登録日2013-08-21
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes.
Plos One, 8, 2013
5V4N
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BU of 5v4n by Molmil
Structure of HLA-DR1 with bound alpha3(135-145) peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, alpha3(135-145)-HLA-DRB1*01:01
著者Petersen, J, Rossjohn, J.
登録日2017-03-10
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.405 Å)
主引用文献Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017
7JU7
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The crystal structure of SARS-CoV-2 Main Protease in complex with masitinib
分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Tan, K, Maltseva, N.I, Welk, L.F, Jedrzejczak, R.P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-08-19
公開日2020-09-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2.
Science, 373, 2021
5V4M
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Structure of HLA-DR15 with bound alpha3(135-145) peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA-DRA1, ...
著者Petersen, J, Rossjohn, J.
登録日2017-03-10
公開日2017-05-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Nature, 545, 2017

 

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