1SKU
 
 | | E. coli Aspartate Transcarbamylase 240's Loop Mutant (K244N) | | 分子名称: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, MALONATE ION, ... | | 著者 | Alam, N, Stieglitz, K.A, Caban, M.D, Gourinath, S, Tsuruta, H, Kantrowitz, E.R. | | 登録日 | 2004-03-05 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | 240s Loop Interactions Stabilize the T State of Escherichia coli Aspartate Transcarbamoylase.
J.Biol.Chem., 279, 2004
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2NXQ
 | | Crystal structure of calcium binding protein 1 from Entamoeba histolytica: a novel arrangement of EF hand motifs | | 分子名称: | ACETATE ION, CALCIUM ION, Calcium-binding protein | | 著者 | Kumar, S, Padhan, N, Alam, N, Gourinath, S. | | 登録日 | 2006-11-18 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of calcium binding protein-1 from Entamoeba histolytica: A novel arrangement of EF hand motifs.
Proteins, 68, 2007
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2PQM
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8IZH
 | | Crystal structure of trypsin-aminoguanidine complex at 2.30 Angstroms resolution | | 分子名称: | AMINOGUANIDINE, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Ahmad, M.S, Kalam, N, Akbar, Z, Rasheed, S, Choudhary, M.I. | | 登録日 | 2023-04-07 | | 公開日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for the binding of famotidine, cimetidine, guanidine, and pimagedine with serine protease.
Biochem.Biophys.Res.Commun., 733, 2024
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8IZI
 | | Crystal structure of trypsin-cimetidine complex at 2.10 Angstroms resolution | | 分子名称: | 2-cyano-1-methyl-3-[2-[(5-methyl-1~{H}-imidazol-4-yl)methylsulfanyl]ethyl]guanidine, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Ahmad, M.S, Kalam, N, Akbar, Z, Rasheed, S, Choudhary, M.I. | | 登録日 | 2023-04-07 | | 公開日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the binding of famotidine, cimetidine, guanidine, and pimagedine with serine protease.
Biochem.Biophys.Res.Commun., 733, 2024
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8IYV
 | | Crystal structure of trypsin-famotidine complex at 2.10 Angstroms resolution | | 分子名称: | CALCIUM ION, CHLORIDE ION, Cationic trypsin, ... | | 著者 | Ahmad, M.S, Kalam, N, Akbar, Z, Rasheed, S, Choudhary, M.I. | | 登録日 | 2023-04-06 | | 公開日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for the binding of famotidine, cimetidine, guanidine, and pimagedine with serine protease.
Biochem.Biophys.Res.Commun., 733, 2024
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8IZK
 | | Crystal structure of trypsin-guanidine complex at 2.05 Angstroms resolution | | 分子名称: | CALCIUM ION, CHLORIDE ION, Cationic trypsin, ... | | 著者 | Ahmad, M.S, Kalam, N, Akbar, Z, Rasheed, S, Choudhary, M.I. | | 登録日 | 2023-04-07 | | 公開日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for the binding of famotidine, cimetidine, guanidine, and pimagedine with serine protease.
Biochem.Biophys.Res.Commun., 733, 2024
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1B1U
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5XOP
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3BM5
 | | Crystal structure of O-acetyl-serine sulfhydrylase from Entamoeba histolytica in complex with cysteine | | 分子名称: | CYSTEINE, Cysteine synthase, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Krishna, C, Kumar, M, Kumar, S, Gourinath, S. | | 登録日 | 2007-12-12 | | 公開日 | 2008-04-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of native O-acetyl-serine sulfhydrylase from Entamoeba histolytica and its complex with cysteine: structural evidence for cysteine binding and lack of interactions with serine acetyl transferase.
Proteins, 72, 2008
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5N71
 | | CRYSTAL STRUCTURE OF MATURE CATHEPSIN D FROM THE TICK IXODES RICINUS (IRCD1) | | 分子名称: | DI(HYDROXYETHYL)ETHER, Putative cathepsin d, SULFATE ION | | 著者 | Brynda, J, Hanova, I, Hobizalova, R, Mares, M. | | 登録日 | 2017-02-17 | | 公開日 | 2017-12-27 | | 最終更新日 | 2018-03-28 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite.
Cell Chem Biol, 25, 2018
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5N7Q
 | | CRYSTAL STRUCTURE OF MATURE CATHEPSIN D FROM THE TICK IXODES RICINUS (IRCD1) IN COMPLEX WITH THE INHIBITOR PEPSTATIN A | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, PEPSTATIN A, ... | | 著者 | Brynda, J, Hanova, I, Hobizalova, R, Mares, M. | | 登録日 | 2017-02-21 | | 公開日 | 2017-12-27 | | 最終更新日 | 2018-06-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite.
Cell Chem Biol, 25, 2018
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5N70
 | | CRYSTAL STRUCTURE OF MATURE CATHEPSIN D FROM THE TICK IXODES RICINUS (IRCD1) IN COMPLEX WITH THE N-TERMINAL OCTAPEPTIDE OF THE PROPEPTID | | 分子名称: | ALA-PHE-ARG-ILE-PRO-LEU-THR-ARG, Putative cathepsin d | | 著者 | Brynda, J, Hanova, I, Hobizalova, R, Mares, M. | | 登録日 | 2017-02-17 | | 公開日 | 2017-12-27 | | 最終更新日 | 2018-03-28 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite.
Cell Chem Biol, 25, 2018
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5N7N
 | | CRYSTAL STRUCTURE OF CATHEPSIN D ZYMOGEN FROM THE TICK IXODES RICINUS (IRCD1) | | 分子名称: | AMMONIUM ION, Putative cathepsin d, SULFATE ION | | 著者 | Brynda, J, Hanova, I, Hobizalova, R, Mares, M. | | 登録日 | 2017-02-21 | | 公開日 | 2017-12-27 | | 最終更新日 | 2018-03-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite.
Cell Chem Biol, 25, 2018
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8CDE
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8CDD
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8CCX
 | | Human SOD1 in complex with S-XL6 cross-linker | | 分子名称: | COPPER (II) ION, DIMETHYL SULFOXIDE, SULFATE ION, ... | | 著者 | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | | 登録日 | 2023-01-27 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.665 Å) | | 主引用文献 | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
Plos Biol., 22, 2024
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4LQQ
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4LQP
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4LQS
 | | Crystal structure of the Cbk1-Mob2 kinase-coactivator complex | | 分子名称: | CBK1 kinase activator protein MOB2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase CBK1 | | 著者 | Gogl, G, Remenyi, A. | | 登録日 | 2013-07-19 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The Structure of an NDR/LATS Kinase-Mob Complex Reveals a Novel Kinase-Coactivator System and Substrate Docking Mechanism.
Plos Biol., 13, 2015
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4HZD
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8Q6M
 | | Human SOD1 low dose data collecton | | 分子名称: | ACETATE ION, COPPER (II) ION, SULFATE ION, ... | | 著者 | Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S. | | 登録日 | 2023-08-14 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
Plos Biol., 22, 2024
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4HZC
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1XJW
 | | The Structure of E. coli Aspartate Transcarbamoylase Q137A Mutant in The R-State | | 分子名称: | Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... | | 著者 | Stieglitz, K.A, Alam, N, Xia, J, Gourinath, S, Tsuruta, H, Kantrowitz, E.R. | | 登録日 | 2004-09-25 | | 公開日 | 2005-05-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | A Single Amino Acid Substitution in the Active Site of Escherichia coli Aspartate Transcarbamoylase Prevents the Allosteric Transition.
J.Mol.Biol., 349, 2005
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