6Z1I
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6Z1O
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7NSL
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6IC3
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![BU of 6ic3 by Molmil](/molmil-images/mine/6ic3) | AL amyloid fibril from a lambda 1 light chain | 分子名称: | lambda 1 light chain fragment, residues 3-118 | 著者 | Fritz, G, Faendrich, M, Schmidt, M, Radamaker, L. | 登録日 | 2018-12-02 | 公開日 | 2019-04-03 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis. Nat Commun, 10, 2019
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8CQT
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![BU of 8cqt by Molmil](/molmil-images/mine/8cqt) | Flavin mononucleotide-dependent nitroreductase B.thetaiotaomicron (BT_1316) | 分子名称: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, Putative NADH dehydrogenase/NAD(P)H nitroreductase | 著者 | Blaha, J, Adam, L, Beckham, K.S.H, Chojnowski, G, Wilmanns, M, Zimmermann, M. | 登録日 | 2023-03-07 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into the diversity of nitroreductase enzymes in Bacteroides thetaiotaomicron To Be Published
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8CQV
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![BU of 8cqv by Molmil](/molmil-images/mine/8cqv) | Flavin mononucleotide-dependent nitroreductase B.thetaiotaomicron (BT_3392) | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, ... | 著者 | Blaha, J, Adam, L, Beckham, K.S.H, Chojnowski, G, Wilmanns, M, Zimmermann, M. | 登録日 | 2023-03-07 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insights into the diversity of nitroreductase enzymes in Bacteroides thetaiotaomicron To Be Published
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8CQU
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![BU of 8cqu by Molmil](/molmil-images/mine/8cqu) | Flavin mononucleotide-dependent nitroreductase B.thetaiotaomicron (BT_1680) | 分子名称: | CITRIC ACID, Putative NADH dehydrogenase/NAD(P)H nitroreductase, TERTIARY-BUTYL ALCOHOL | 著者 | Blaha, J, Adam, L, Beckham, K.S.H, Chojnowski, G, Wilmanns, M, Zimmermann, M. | 登録日 | 2023-03-07 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the diversity of nitroreductase enzymes in Bacteroides thetaiotaomicron To Be Published
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4WKE
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![BU of 4wke by Molmil](/molmil-images/mine/4wke) | Crystal structure of human ADAMTS-4 in complex with inhibitor 5-chloro-N-{[(4R)-2,5-dioxo-4-(1,3-thiazol-2-yl)imidazolidin-4-yl]methyl}-1-benzofuran-2-carboxamide (compound 10) | 分子名称: | 1,2-ETHANEDIOL, 5-chloro-N-{[(4R)-2,5-dioxo-4-(1,3-thiazol-2-yl)imidazolidin-4-yl]methyl}-1-benzofuran-2-carboxamide, A disintegrin and metalloproteinase with thrombospondin motifs 4, ... | 著者 | Durbin, J.D. | 登録日 | 2014-10-02 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Identification of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 that are efficacious in both chemical and surgical models of osteoarthritis. J.Med.Chem., 57, 2014
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4WKI
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8CQS
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![BU of 8cqs by Molmil](/molmil-images/mine/8cqs) | Flavin mononucleotide-dependent nitroreductase B.thetaiotaomicron (BT_0217) | 分子名称: | FLAVIN MONONUCLEOTIDE, Nitroreductase-like protein, PHOSPHATE ION | 著者 | Blaha, J, Gratzl, S, Mortensen, S.A, Beckham, K.S.H, Chojnowski, G, Wilmanns, M, Zimmermann, M. | 登録日 | 2023-03-07 | 公開日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insights into the diversity of nitroreductase enzymes in Bacteroides thetaiotaomicron To Be Published
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6SUW
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6SV1
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4WK7
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![BU of 4wk7 by Molmil](/molmil-images/mine/4wk7) | Crystal structure of human ADAMTS-4 in complex with inhibitor (compound 1, 2-(4-chlorophenoxy)-N-{[(4R)-4-methyl-2,5-dioxoimidazolidin-4-yl]methyl} acetamide) | 分子名称: | 2-(4-chlorophenoxy)-N-{[(4R)-4-methyl-2,5-dioxoimidazolidin-4-yl]methyl}acetamide, A disintegrin and metalloproteinase with thrombospondin motifs 4, CALCIUM ION, ... | 著者 | Durbin, J.D, Stout, S.L. | 登録日 | 2014-10-01 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Identification of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 that are efficacious in both chemical and surgical models of osteoarthritis. J.Med.Chem., 57, 2014
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4ALU
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![BU of 4alu by Molmil](/molmil-images/mine/4alu) | Benzofuropyrimidinone Inhibitors of Pim-1 | 分子名称: | 8-bromo-2-(2-chlorophenyl)[1]benzofuro[3,2-d]pyrimidin-4(3H)-one, IMIDAZOLE, SERINE/THREONINE-PROTEIN KINASE PIM-1 | 著者 | Stout, T.J, Adams, L. | 登録日 | 2012-03-05 | 公開日 | 2013-01-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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4ALW
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![BU of 4alw by Molmil](/molmil-images/mine/4alw) | Benzofuropyrimidinone Inhibitors of Pim-1 | 分子名称: | 8-BROMANYL-2-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3H-[1]BENZOFURO[3,2-D]PYRIMIDIN-4-ONE, IMIDAZOLE, PIM-1 KINASE | 著者 | Stout, T.J, Adams, L. | 登録日 | 2012-03-05 | 公開日 | 2013-01-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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4ALV
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![BU of 4alv by Molmil](/molmil-images/mine/4alv) | Benzofuropyrimidinone Inhibitors of Pim-1 | 分子名称: | 8-bromo-2-{2-chloro-4-[(piperidin-4-ylmethyl)amino]phenyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one, IMIDAZOLE, SERINE/THREONINE-PROTEIN KINASE PIM-1 | 著者 | Stout, T.J, Adams, L. | 登録日 | 2012-03-05 | 公開日 | 2013-01-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | The Design, Synthesis, and Biological Evaluation of Pim Kinase Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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8U7U
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![BU of 8u7u by Molmil](/molmil-images/mine/8u7u) | Proteasome 20S Core Particle from Beta 3 D205 deletion | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | 著者 | Walsh Jr, R.M, Rawson, S, Velez, B, Blickling, M, Razi, A, Hanna, J. | 登録日 | 2023-09-15 | 公開日 | 2024-04-17 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.16 Å) | 主引用文献 | Mechanism of autocatalytic activation during proteasome assembly. Nat.Struct.Mol.Biol., 2024
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8U6Y
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![BU of 8u6y by Molmil](/molmil-images/mine/8u6y) | Preholo-Proteasome from Beta 3 D205 deletion | 分子名称: | Proteasome assembly chaperone 2, Proteasome chaperone 1, Proteasome maturation factor UMP1, ... | 著者 | Walsh Jr, R.M, Rawson, S, Velez, B, Blickling, M, Razi, A, Hanna, J. | 登録日 | 2023-09-14 | 公開日 | 2024-04-17 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Mechanism of autocatalytic activation during proteasome assembly. Nat.Struct.Mol.Biol., 2024
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7MKM
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7MKL
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4AOC
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![BU of 4aoc by Molmil](/molmil-images/mine/4aoc) | crystal structure of BC2L-A Lectin from Burkolderia cenocepacia in complex with methyl-heptoside | 分子名称: | BC2L-A LECTIN, CALCIUM ION, SULFATE ION, ... | 著者 | Marchetti, R, Malinovska, L, Lameignere, E, deCastro, C, Cioci, G, Kosma, P, Wimmerova, M, Molinaro, A, Imberty, A, Silipo, A. | 登録日 | 2012-03-26 | 公開日 | 2012-08-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Burkholderia Cenocepacia Lectin a Binding to Heptoses from the Bacterial Lipopolysaccharide. Glycobiology, 22, 2012
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7LII
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![BU of 7lii by Molmil](/molmil-images/mine/7lii) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S7D | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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7LIL
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![BU of 7lil by Molmil](/molmil-images/mine/7lil) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant SE3 | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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7LIM
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![BU of 7lim by Molmil](/molmil-images/mine/7lim) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S6E | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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7LIJ
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![BU of 7lij by Molmil](/molmil-images/mine/7lij) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S1K | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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