1YF5
| Cyto-Epsl: The Cytoplasmic Domain Of Epsl, An Inner Membrane Component Of The Type II Secretion System Of Vibrio Cholerae | 分子名称: | General secretion pathway protein L | 著者 | Abendroth, J, Murphy, P, Mushtaq, A, Sandkvist, M, Bagdasarian, M, Hol, W.G. | 登録日 | 2004-12-30 | 公開日 | 2005-05-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | The X-ray Structure of the Type II Secretion System Complex Formed by the N-terminal Domain of EpsE and the Cytoplasmic Domain of EpsL of Vibrio cholerae. J.Mol.Biol., 348, 2005
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3C1Q
| The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Abendroth, J, Mitchell, D.D, Korotkov, K.V, Kreeger, A, Hol, W.G.J. | 登録日 | 2008-01-24 | 公開日 | 2009-02-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The three-dimensional structure of the cytoplasmic domains of EpsF from the type 2 secretion system of Vibrio cholerae J.Struct.Biol., 166, 2009
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2BH1
| X-ray structure of the general secretion pathway complex of the N- terminal domain of EpsE and the cytosolic domain of EpsL of Vibrio cholerae | 分子名称: | CALCIUM ION, GENERAL SECRETION PATHWAY PROTEIN E,, GENERAL SECRETION PATHWAY PROTEIN L | 著者 | Abendroth, J, Murphy, P.M, Mushtaq, A, Bagdasarian, M, Sandkvist, M, Hol, W.G.J. | 登録日 | 2005-01-06 | 公開日 | 2005-05-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The X-Ray Structure of the Type II Secretion System Complex Formed by the N-Terminal Domain of Epse and the Cytoplasmic Domain of Epsl of Vibrio Cholerae J.Mol.Biol., 348, 2005
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1UV7
| periplasmic domain of EpsM from Vibrio cholerae | 分子名称: | GENERAL SECRETION PATHWAY PROTEIN M | 著者 | Abendroth, J, Hol, W.G.J. | 登録日 | 2004-01-15 | 公開日 | 2004-04-23 | 最終更新日 | 2019-05-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Crystal Structure of the Periplasmic Domain of the Type II Secretion System Protein Epsm from Vibrio Cholerae: The Simplest Version of the Ferredoxin Fold J.Mol.Biol., 338, 2004
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1GKP
| D-Hydantoinase (Dihydropyrimidinase) from Thermus sp. in space group C2221 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HYDANTOINASE, SULFATE ION, ... | 著者 | Abendroth, J, Niefind, K, Schomburg, D. | 登録日 | 2001-08-20 | 公開日 | 2002-06-27 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.295 Å) | 主引用文献 | X-Ray Structure of a Dihydropyrimidinase from Thermus Sp. At 1.3 A Resolution J.Mol.Biol., 320, 2002
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1W97
| cyto-EpsL: the cytoplasmic domain of EpsL, an inner membrane component of the type II secretion system of Vibrio cholerae | 分子名称: | TYPE II SECRETION SYSTEM PROTEIN L | 著者 | Abendroth, J, Bagdasarian, M, Sansdkvist, M, Hol, W.G.J. | 登録日 | 2004-10-06 | 公開日 | 2004-11-30 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The Structure of the Cytoplasmic Domain of Epsl, an Inner Membrane Component of the Type II Secretion System of Vibrio Cholerae: An Unusual Member of the Actin-Like ATPase Superfamily J.Mol.Biol., 344, 2004
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2W7V
| periplasmic domain of EpsL from Vibrio parahaemolyticus | 分子名称: | 1,2-ETHANEDIOL, GENERAL SECRETION PATHWAY PROTEIN L, PHOSPHATE ION | 著者 | Abendroth, J, Kreger, A.C, Abendroth, H, Sandkvist, M, Hol, W.G.J. | 登録日 | 2009-01-06 | 公開日 | 2010-03-31 | 最終更新日 | 2017-06-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Dimer Formed by the Periplasmic Domain of Epsl from the Type 2 Secretion System of Vibrio Parahaemolyticus. J.Struct.Biol., 168, 2009
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1GKQ
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1GKR
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2VMB
| The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae | 分子名称: | CALCIUM ION, GENERAL SECRETION PATHWAY PROTEIN F | 著者 | Abendroth, J, Korotkov, K.V, Mitchell, D.D, Kreger, A, Hol, W.G.J. | 登録日 | 2008-01-25 | 公開日 | 2009-02-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Three-Dimensional Structure of the Cytoplasmic Domains of Epsf from the Type 2 Secretion System of Vibrio Cholerae. J.Struct.Biol., 166, 2009
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2VMA
| The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae | 分子名称: | CALCIUM ION, GENERAL SECRETION PATHWAY PROTEIN F, IODIDE ION | 著者 | Abendroth, J, Korotkov, K.V, Mitchell, D.D, Kreger, A, Hol, W.G.J. | 登録日 | 2008-01-25 | 公開日 | 2009-02-10 | 最終更新日 | 2017-06-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Three-Dimensional Structure of the Cytoplasmic Domains of Epsf from the Type 2 Secretion System of Vibrio Cholerae. J.Struct.Biol., 166, 2009
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3K2E
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8DSR
| Structure of Plasmepsin X (PM10, PMX) from Plasmodium falciparum 3D7 in complex with UCB7362 | 分子名称: | (2E,6S)-6-{2-chloro-3-[(2-cyclopropylpyrimidin-5-yl)amino]phenyl}-2-imino-6-methyl-3-[(2S,4S)-2-methyloxan-4-yl]-1,3-diazinan-4-one, Plasmepsin X | 著者 | Abendroth, J, Lorimer, D.D. | 登録日 | 2022-07-22 | 公開日 | 2022-10-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of UCB7362 . J.Med.Chem., 65, 2022
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6MOM
| Crystal structure of human Interleukin-1 receptor associated Kinase 4 (IRAK 4, CID 100300) in complex with compound NCC00371481 (BSI 107591) | 分子名称: | 1,2-ETHANEDIOL, 6-[7-methoxy-6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]-N-[(3R)-pyrrolidin-3-yl]pyridin-2-amine, Interleukin-1 receptor-associated kinase 4 | 著者 | Abendroth, J, Mayclin, S.J, Lorimer, D.D, Starczynowski, D, Hoyt, S, Tawa, G, Thomas, C. | 登録日 | 2018-10-04 | 公開日 | 2019-10-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Overcoming adaptive therapy resistance in AML by targeting immune response pathways. Sci Transl Med, 11, 2019
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3GMT
| Crystal structure of adenylate kinase from burkholderia pseudomallei | 分子名称: | Adenylate kinase, SULFATE ION | 著者 | Abendroth, J, Staker, B.L, Robinson, H, Buchko, G.W, Hewitt, S.N, Napuli, A.J, Van Voorhis, W, Stacy, R, Myler, P.J, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2009-03-15 | 公開日 | 2009-06-02 | 最終更新日 | 2013-10-30 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural characterization of Burkholderia pseudomallei adenylate kinase (Adk): profound asymmetry in the crystal structure of the 'open' state. Biochem.Biophys.Res.Commun., 394, 2010
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4PUB
| Crystal structure of Fab DX-2930 | 分子名称: | CHLORIDE ION, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN | 著者 | Abendroth, J, Edwards, T.E, Nixon, A, Ladner, R. | 登録日 | 2014-03-12 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
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3LRF
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3IFT
| Crystal structure of glycine cleavage system protein H from Mycobacterium tuberculosis, using X-rays from the Compact Light Source. | 分子名称: | Glycine cleavage system H protein | 著者 | Edwards, T.E, Abendroth, J, Staker, B, Mayer, C, Phan, I, Kelley, A, Analau, E, Leibly, D, Rifkin, J, Loewen, R, Ruth, R.D, Stewart, L.J, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | 登録日 | 2009-07-25 | 公開日 | 2009-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source. J.Struct.Funct.Genom., 11, 2010
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3NNX
| Crystal structure of phosphorylated P38 alpha in complex with DP802 | 分子名称: | 2-[3-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-2,5-dihydro-1H-pyrazol-1-yl)phenyl]acetamide, Mitogen-activated protein kinase 14 | 著者 | Abendroth, J. | 登録日 | 2010-06-24 | 公開日 | 2010-09-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region Bioorg.Med.Chem.Lett., 20, 2010
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3NNW
| Crystal structure of P38 alpha in complex with DP802 | 分子名称: | 2-[3-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-2,5-dihydro-1H-pyrazol-1-yl)phenyl]acetamide, Mitogen-activated protein kinase 14 | 著者 | Abendroth, J. | 登録日 | 2010-06-24 | 公開日 | 2010-09-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region Bioorg.Med.Chem.Lett., 20, 2010
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3NNV
| Crystal structure of P38 alpha in complex with DP437 | 分子名称: | 1-{3-tert-butyl-1-[4-(hydroxymethyl)phenyl]-1H-pyrazol-5-yl}-3-naphthalen-1-ylurea, Mitogen-activated protein kinase 14 | 著者 | Abendroth, J. | 登録日 | 2010-06-24 | 公開日 | 2010-09-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region Bioorg.Med.Chem.Lett., 20, 2010
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3NNU
| Crystal structure of P38 alpha in complex with DP1376 | 分子名称: | 2-{3-[(5E)-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-3-thiophen-2-yl-2,5-dihydro-1H-pyrazol-1-yl]phenyl}acetamide, Mitogen-activated protein kinase 14 | 著者 | Abendroth, J. | 登録日 | 2010-06-24 | 公開日 | 2010-09-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Switch control pocket inhibitors of p38-MAP kinase. Durable type II inhibitors that do not require binding into the canonical ATP hinge region Bioorg.Med.Chem.Lett., 20, 2010
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1K1D
| Crystal structure of D-hydantoinase | 分子名称: | D-hydantoinase, ZINC ION | 著者 | Cheon, Y.H, Kim, H.S, Han, K.H, Abendroth, J, Niefind, K, Schomburg, D, Wang, J, Kim, Y. | 登録日 | 2001-09-25 | 公開日 | 2002-08-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Crystal structure of D-hydantoinase from Bacillus stearothermophilus: insight into the stereochemistry of enantioselectivity. Biochemistry, 41, 2002
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7RBX
| Crystal structure of isocitrate lyase and phosphorylmutase:isocitrate lyase from Brucella melitensis biovar Abortus 2308 bound to itaconic acid | 分子名称: | 1,2-ETHANEDIOL, 2-methylidenebutanedioic acid, Isocitrase, ... | 著者 | Seattle Structural Genomics Center for Infectious Disease, Edwards, T.E, Abendroth, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2021-07-06 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Aconitate decarboxylase 1 participates in the control of pulmonary Brucella infection in mice. Plos Pathog., 17, 2021
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4XIN
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