1U6T
| Crystal structure of the human SH3 binding glutamic-rich protein like | 分子名称: | CITRIC ACID, SH3 domain-binding glutamic acid-rich-like protein | 著者 | Yin, L, Xiang, Y, Yang, N, Zhu, D.-Y, Huang, R.-H, Wang, D.-C. | 登録日 | 2004-08-01 | 公開日 | 2005-08-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of human SH3BGRL protein: the first structure of the human SH3BGR family representing a novel class of thioredoxin fold proteins Proteins, 61, 2005
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8E5D
| Crystal structure of double-stranded DNA deaminase toxin DddA in complex with DNA with the target cytosine parked in the major groove | 分子名称: | DNA (5'-D(*GP*TP*AP*CP*CP*GP*GP*AP*CP*GP*TP*TP*GP*C)-3'), Double-stranded DNA deaminase toxin A, MAGNESIUM ION, ... | 著者 | Yin, L, Shi, K, Aihara, H. | 登録日 | 2022-08-21 | 公開日 | 2023-05-24 | 最終更新日 | 2024-09-18 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Structural basis of sequence-specific cytosine deamination by double-stranded DNA deaminase toxin DddA. Nat.Struct.Mol.Biol., 30, 2023
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8E5E
| Crystal structure of double-stranded DNA deaminase toxin DddA in complex with DNA with the target cytosine flipped into the active site | 分子名称: | DNA (5'-D(*GP*CP*AP*AP*CP*GP*TP*CP*CP*GP*GP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*CP*CP*GP*GP*AP*CP*GP*TP*TP*GP*C)-3'), Double-stranded DNA deaminase toxin A, ... | 著者 | Yin, L, Shi, K, Aihara, H. | 登録日 | 2022-08-21 | 公開日 | 2023-05-24 | 最終更新日 | 2024-09-18 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structural basis of sequence-specific cytosine deamination by double-stranded DNA deaminase toxin DddA. Nat.Struct.Mol.Biol., 30, 2023
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5XN7
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7XGB
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6QNS
| Crystal structure of the binding domain of Botulinum Neurotoxin type B mutant I1248W/V1249W in complex with human synaptotagmin 1 and GD1a receptors | 分子名称: | Botulinum neurotoxin type B, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, Synaptotagmin-1 | 著者 | Masuyer, G, Yin, L, Zhang, S, Miyashita, S.I, Dong, M, Stenmark, P. | 登録日 | 2019-02-12 | 公開日 | 2020-02-26 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy. Plos Biol., 18, 2020
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8EJO
| Crystal structure of the homeodomain of Platypus sDUX in complex with DNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ... | 著者 | Yin, L, Shi, K, Aihara, H. | 登録日 | 2022-09-18 | 公開日 | 2023-09-20 | 最終更新日 | 2024-09-18 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein. Iscience, 26, 2023
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8EJP
| Crystal structure of the homeodomain of Platypus sDUX in complex with DNA containing 5-Bromouracil | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ... | 著者 | Yin, L, Shi, K, Aihara, H. | 登録日 | 2022-09-18 | 公開日 | 2023-09-20 | 最終更新日 | 2024-09-18 | 実験手法 | X-RAY DIFFRACTION (2.174 Å) | 主引用文献 | Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein. Iscience, 26, 2023
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4H1L
| TCR interaction with peptide mimics of nickel offers structural insights in nickel contact allergy | 分子名称: | Ani2.3 TCR A chain, Ani2.3 TCR B chain, HLA class II histocompatibility antigen, ... | 著者 | Kappler, J.W, Yin, L, Dai, S, Marrack, P. | 登録日 | 2012-09-10 | 公開日 | 2012-11-14 | 最終更新日 | 2013-09-04 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
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4H26
| TCR interaction with peptide mimics of nickel offers structure insight to nickel contact allergy | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F. | 登録日 | 2012-09-12 | 公開日 | 2013-10-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
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4HEH
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4H25
| TCR interaction with peptide mimics of nickel offers structure insights to nickel contact allergy | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F. | 登録日 | 2012-09-12 | 公開日 | 2013-10-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
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3RGV
| A single TCR bound to MHCI and MHC II reveals switchable TCR conformers | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | 著者 | Dai, S, Huseby, E, Scott-Browne, J, Rubtsova, K, Pinilla, C, Crawford, F, Marrack, P, Yin, L, Kappler, J.W. | 登録日 | 2011-04-09 | 公開日 | 2011-07-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers. Immunity, 35, 2011
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4OV5
| Structure of HLA-DR1 with a bound peptide with non-optimal alanine in the P1 pocket | 分子名称: | HLA class I histocompatibility antigen, A-2 alpha chain, HLA class II histocompatibility antigen, ... | 著者 | Trenh, P, Yin, L, Stern, L.J. | 登録日 | 2014-02-20 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide. J.Biol.Chem., 289, 2014
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6JJ4
| Crystal structure of OsHXK6-apo form | 分子名称: | Hexokinase-6 | 著者 | He, C, Wei, P, Chen, J, Wang, H, Wan, Y, Zhou, J, Zhu, Y, Huang, W, Yin, L. | 登録日 | 2019-02-25 | 公開日 | 2019-07-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of OsHXK6-apo To Be Published
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6JJ9
| Crystal structure of OsHXK6-Glc-ATP-Mg2+ complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Hexokinase-6, MAGNESIUM ION, ... | 著者 | He, C, Wei, P, Chen, J, Wang, H, Wan, Y, Zhou, J, Zhu, Y, Huang, W, Yin, L. | 登録日 | 2019-02-25 | 公開日 | 2019-07-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of OsHXK6-Glc-ATP-Mg2+ complex To Be Published
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6JQ2
| Crystal Structure of H2-Kb in complex with a DPAGT1 self-peptide | 分子名称: | Beta-2-microglobulin, DPATG1 antigen SIIVFNLV, H-2 class I histocompatibility antigen, ... | 著者 | Bai, P, Yin, L. | 登録日 | 2019-03-28 | 公開日 | 2020-04-01 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
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6JQ3
| Crystal Structure of H2-Kb in complex with a DPAGT1 mutant peptide | 分子名称: | Beta-2-microglobulin, DPAGT1 mutant antigen SIIVFNLL, H-2 class I histocompatibility antigen, ... | 著者 | Bai, P, Zhou, Q, Wei, P, Yin, L. | 登録日 | 2019-03-28 | 公開日 | 2020-05-06 | 最終更新日 | 2021-02-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
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6JTN
| Crystal structure of HLA-C08 in complex with a tumor mut10m peptide | 分子名称: | 10-mer peptide, Beta-2-microglobulin, HLA class I antigen, ... | 著者 | Bai, P, Zhou, Q, Wei, P, Yin, L. | 登録日 | 2019-04-11 | 公開日 | 2020-04-15 | 最終更新日 | 2021-02-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
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7MC5
| Crystal structure of the SARS-CoV-2 ExoN-nsp10 complex | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, L(+)-TARTARIC ACID, ... | 著者 | Moeller, N.M, Shi, K, Banerjee, S, Yin, L, Aihara, H. | 登録日 | 2021-04-01 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN. Proc.Natl.Acad.Sci.USA, 119, 2022
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7MC6
| Crystal structure of the SARS-CoV-2 ExoN-nsp10 complex containing Mg2+ ion | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Moeller, N.M, Shi, K, Banerjee, S, Yin, L, Aihara, H. | 登録日 | 2021-04-01 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN. Proc.Natl.Acad.Sci.USA, 119, 2022
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3NI2
| Crystal structures and enzymatic mechanisms of a Populus tomentosa 4-coumarate:CoA ligase | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-coumarate:CoA ligase, 5'-O-{(S)-hydroxy[3-(4-hydroxyphenyl)propoxy]phosphoryl}adenosine | 著者 | Hu, Y, Yin, L, Gai, Y, Wang, X.X, Wang, D.C. | 登録日 | 2010-06-14 | 公開日 | 2010-09-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of a Populus tomentosa 4-coumarate:CoA ligase shed light on its enzymatic mechanisms Plant Cell, 22, 2010
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5YLF
| MCR-1 complex with D-glucose | 分子名称: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION, beta-D-glucopyranose | 著者 | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | 登録日 | 2017-10-17 | 公開日 | 2017-11-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance. FASEB J., 32, 2018
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5YLC
| Crystal Structure of MCR-1 Catalytic Domain | 分子名称: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | 著者 | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | 登録日 | 2017-10-17 | 公開日 | 2017-11-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance. FASEB J., 32, 2018
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5YLE
| MCR-1 complex with ethanolamine (ETA) | 分子名称: | ETHANOLAMINE, Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | 著者 | Wei, P.C, Song, G.J, Shi, M.Y, Zhou, Y.F, Liu, Y, Lei, J, Chen, P, Yin, L. | 登録日 | 2017-10-17 | 公開日 | 2017-11-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Substrate analog interaction with MCR-1 offers insight into the rising threat of the plasmid-mediated transferable colistin resistance. FASEB J., 32, 2018
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