8E5D

Crystal structure of double-stranded DNA deaminase toxin DddA in complex with DNA with the target cytosine parked in the major groove

Summary for 8E5D

• Entry DOI: 10.2210/pdb8e5d/pdb
• Descriptor: Double-stranded DNA deaminase toxin A, DNA (5'-D(*GP*TP*AP*CP*CP*GP*GP*AP*CP*GP*TP*TP*GP*C)-3'), ZINC ION, ... (7 entities in total)
• Functional Keywords: toxin, dna binding, deaminase, toxin-dna complex, toxin/dna
• Biological source: Burkholderia cenocepacia; More
• Total number of polymer chains: 3
• Total formula weight: 23433.47

Authors

Yin, L.L.,Shi, K.,Aihara, H. (deposition date: 2022-08-21, release date: 2023-05-24, Last modification date: 2023-10-25)

• Primary citation: Yin, L.,Shi, K.,Aihara, H.; Structural basis of sequence-specific cytosine deamination by double-stranded DNA deaminase toxin DddA.; Nat.Struct.Mol.Biol., 30:1153-1159, 2023; PubMed: 37460895; DOI: 10.1038/s41594-023-01034-3

Experimental method

X-RAY DIFFRACTION (2.39 Å)