1FNT
| CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST IN COMPLEX WITH THE PROTEASOME ACTIVATOR PA26 FROM TRYPANOSOME BRUCEI AT 3.2 ANGSTROMS RESOLUTION | 分子名称: | MAGNESIUM ION, PROTEASOME ACTIVATOR PROTEIN PA26, PROTEASOME COMPONENT C1, ... | 著者 | Whitby, F.G, Masters, E, Kramer, L, Knowlton, J.R, Yao, Y, Wang, C.C, Hill, C.P. | 登録日 | 2000-08-23 | 公開日 | 2001-04-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the activation of 20S proteasomes by 11S regulators. Nature, 408, 2000
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1C1G
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1AK5
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1LC3
| Crystal Structure of a Biliverdin Reductase Enzyme-Cofactor Complex | 分子名称: | Biliverdin Reductase A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION | 著者 | Whitby, F.G, Phillips, J.D, Hill, C.P, McCoubrey, W, Maines, M.D. | 登録日 | 2002-04-05 | 公開日 | 2002-07-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex. J.Mol.Biol., 319, 2002
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1LC0
| Structure of Biliverdin Reductase and the Enzyme-NADH Complex | 分子名称: | Biliverdin Reductase A, PHOSPHATE ION | 著者 | Whitby, F.G, Phillips, J.D, Hill, C.P, McCoubrey, W, Maines, M.D. | 登録日 | 2002-04-04 | 公開日 | 2002-07-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex. J.Mol.Biol., 319, 2002
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1NDD
| STRUCTURE OF NEDD8 | 分子名称: | CHLORIDE ION, PROTEIN (UBIQUITIN-LIKE PROTEIN NEDD8), SULFATE ION | 著者 | Whitby, F.G, Xia, G, Pickart, C.M, Hill, C.P. | 登録日 | 1998-08-21 | 公開日 | 1999-02-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes. J.Biol.Chem., 273, 1998
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1URO
| UROPORPHYRINOGEN DECARBOXYLASE | 分子名称: | BETA-MERCAPTOETHANOL, PROTEIN (UROPORPHYRINOGEN DECARBOXYLASE) | 著者 | Whitby, F.G, Phillips, J.D, Kushner, J.P, Hill, C.P. | 登録日 | 1998-08-21 | 公開日 | 1998-08-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of human uroporphyrinogen decarboxylase. EMBO J., 17, 1998
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7RCM
| Crystal Structure of ADP-bound Galactokinase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Galactokinase, ... | 著者 | Whitby, F.G. | 登録日 | 2021-07-07 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
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7RCL
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7S4C
| Crystal Structure of Inhibitor-bound Galactokinase | 分子名称: | 2-({(4R)-4-(2-chlorophenyl)-2-[(6-fluoro-1,3-benzoxazol-2-yl)amino]-6-methyl-1,4-dihydropyrimidine-5-carbonyl}amino)pyridine-4-carboxylic acid, Galactokinase, PHOSPHATE ION, ... | 著者 | Whitby, F.G. | 登録日 | 2021-09-08 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
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7S49
| Crystal Structure of Inhibitor-bound Galactokinase | 分子名称: | (4R)-2-[(1,3-benzoxazol-2-yl)amino]-4-(4-chloro-1H-pyrazol-5-yl)-4,6,7,8-tetrahydroquinazolin-5(1H)-one, Galactokinase, PHOSPHATE ION, ... | 著者 | Whitby, F.G. | 登録日 | 2021-09-08 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
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5ILS
| Autoinhibited ETV1 | 分子名称: | ETS translocation variant 1 | 著者 | Whitby, F.G, Currie, S.L. | 登録日 | 2016-03-04 | 公開日 | 2017-02-22 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
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5ILV
| Uninhibited ETV5 | 分子名称: | ETS translocation variant 5 | 著者 | Whitby, F.G, Currie, S.L. | 登録日 | 2016-03-04 | 公開日 | 2017-02-22 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
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5ILU
| Autoinhibited ETV4 | 分子名称: | ETS translocation variant 4 | 著者 | Whitby, F.G, Currie, S.L. | 登録日 | 2016-03-04 | 公開日 | 2017-02-22 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.101 Å) | 主引用文献 | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
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7SMU
| Crystal Structure of Consomatin-Ro1 | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxaoctatetracontane-1,48-diol, Consomatin-Ro1 | 著者 | Ramiro, I.B.L, Whitby, F.G, Hill, C.P, Safavi-Hemami, H, Concepcion, G.P, Olivera, B.M. | 登録日 | 2021-10-26 | 公開日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads. Sci Adv, 8, 2022
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6E93
| Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 in complex with methylated DNA | 分子名称: | DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ... | 著者 | Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A. | 登録日 | 2018-07-31 | 公開日 | 2018-11-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.747 Å) | 主引用文献 | Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38. J. Biol. Chem., 293, 2018
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8UC6
| Calpain-7:IST1 Complex | 分子名称: | Calpain-7, IST1 homolog | 著者 | Paine, E, Whitby, F.G, Hill, C.P, Sunquist, W.I. | 登録日 | 2023-09-25 | 公開日 | 2023-10-25 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission. Elife, 12, 2023
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7TXE
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7U2V
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6E94
| Crystal Structure of ZBTB38 C-terminal Zinc Fingers 6-9 K1055R in complex with methylated DNA | 分子名称: | DNA (5'-D(*GP*CP*AP*CP*TP*CP*AP*TP*(DCM)P*GP*GP*(DCM)P*GP*CP*AP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*(DCM)P*GP*CP*(DCM)P*GP*AP*TP*GP*AP*GP*TP*GP*C)-3'), ZINC ION, ... | 著者 | Hudson, N.O, Whitby, F.G, Buck-Koehntop, B.A. | 登録日 | 2018-07-31 | 公開日 | 2018-11-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.594 Å) | 主引用文献 | Structural insights into methylated DNA recognition by the C-terminal zinc fingers of the DNA reader protein ZBTB38. J. Biol. Chem., 293, 2018
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2HTH
| Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain | 分子名称: | Ubiquitin, Vacuolar protein sorting protein 36 | 著者 | Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I. | 登録日 | 2006-07-25 | 公開日 | 2006-10-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat.Struct.Mol.Biol., 13, 2006
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3C3O
| ALIX Bro1-domain:CHMIP4A co-crystal structure | 分子名称: | Charged multivesicular body protein 4a peptide, GLYCEROL, Programmed cell death 6-interacting protein | 著者 | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | 登録日 | 2008-01-28 | 公開日 | 2008-06-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C3R
| ALIX BRO1 CHMP4C complex | 分子名称: | Charged multivesicular body protein 4c peptide, GLYCEROL, Programmed cell death 6-interacting protein | 著者 | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | 登録日 | 2008-01-28 | 公開日 | 2008-06-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105, 2008
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4LCB
| Structure of Vps4 homolog from Acidianus hospitalis | 分子名称: | CHLORIDE ION, Cell division protein CdvC, Vps4 | 著者 | Han, H, Hill, C.P, Whitby, F.G, Monroe, N. | 登録日 | 2013-06-21 | 公開日 | 2013-11-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | The Oligomeric State of the Active Vps4 AAA ATPase. J.Mol.Biol., 426, 2014
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4LGM
| Crystal Structure of Sulfolobus solfataricus Vps4 | 分子名称: | CHLORIDE ION, Vps4 AAA ATPase | 著者 | Han, H, Hill, C.P, Whitby, F.G, Monroe, N. | 登録日 | 2013-06-28 | 公開日 | 2013-11-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.711 Å) | 主引用文献 | The Oligomeric State of the Active Vps4 AAA ATPase. J.Mol.Biol., 426, 2014
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