1C1G
 
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1FNT
 | | CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST IN COMPLEX WITH THE PROTEASOME ACTIVATOR PA26 FROM TRYPANOSOME BRUCEI AT 3.2 ANGSTROMS RESOLUTION | | 分子名称: | MAGNESIUM ION, PROTEASOME ACTIVATOR PROTEIN PA26, PROTEASOME COMPONENT C1, ... | | 著者 | Whitby, F.G, Masters, E, Kramer, L, Knowlton, J.R, Yao, Y, Wang, C.C, Hill, C.P. | | 登録日 | 2000-08-23 | | 公開日 | 2001-04-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for the activation of 20S proteasomes by 11S regulators.
Nature, 408, 2000
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1AK5
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1NDD
 | | STRUCTURE OF NEDD8 | | 分子名称: | CHLORIDE ION, PROTEIN (UBIQUITIN-LIKE PROTEIN NEDD8), SULFATE ION | | 著者 | Whitby, F.G, Xia, G, Pickart, C.M, Hill, C.P. | | 登録日 | 1998-08-21 | | 公開日 | 1999-02-23 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes.
J.Biol.Chem., 273, 1998
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1LC3
 | | Crystal Structure of a Biliverdin Reductase Enzyme-Cofactor Complex | | 分子名称: | Biliverdin Reductase A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION | | 著者 | Whitby, F.G, Phillips, J.D, Hill, C.P, McCoubrey, W, Maines, M.D. | | 登録日 | 2002-04-05 | | 公開日 | 2002-07-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex.
J.Mol.Biol., 319, 2002
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1LC0
 | | Structure of Biliverdin Reductase and the Enzyme-NADH Complex | | 分子名称: | Biliverdin Reductase A, PHOSPHATE ION | | 著者 | Whitby, F.G, Phillips, J.D, Hill, C.P, McCoubrey, W, Maines, M.D. | | 登録日 | 2002-04-04 | | 公開日 | 2002-07-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex.
J.Mol.Biol., 319, 2002
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1URO
 | | UROPORPHYRINOGEN DECARBOXYLASE | | 分子名称: | BETA-MERCAPTOETHANOL, PROTEIN (UROPORPHYRINOGEN DECARBOXYLASE) | | 著者 | Whitby, F.G, Phillips, J.D, Kushner, J.P, Hill, C.P. | | 登録日 | 1998-08-21 | | 公開日 | 1998-08-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of human uroporphyrinogen decarboxylase.
EMBO J., 17, 1998
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7RCL
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7RCM
 | | Crystal Structure of ADP-bound Galactokinase | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Galactokinase, ... | | 著者 | Whitby, F.G. | | 登録日 | 2021-07-07 | | 公開日 | 2021-09-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.
J.Med.Chem., 64, 2021
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7S49
 | | Crystal Structure of Inhibitor-bound Galactokinase | | 分子名称: | (4R)-2-[(1,3-benzoxazol-2-yl)amino]-4-(4-chloro-1H-pyrazol-5-yl)-4,6,7,8-tetrahydroquinazolin-5(1H)-one, Galactokinase, PHOSPHATE ION, ... | | 著者 | Whitby, F.G. | | 登録日 | 2021-09-08 | | 公開日 | 2021-09-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.
J.Med.Chem., 64, 2021
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7S4C
 | | Crystal Structure of Inhibitor-bound Galactokinase | | 分子名称: | 2-({(4R)-4-(2-chlorophenyl)-2-[(6-fluoro-1,3-benzoxazol-2-yl)amino]-6-methyl-1,4-dihydropyrimidine-5-carbonyl}amino)pyridine-4-carboxylic acid, Galactokinase, PHOSPHATE ION, ... | | 著者 | Whitby, F.G. | | 登録日 | 2021-09-08 | | 公開日 | 2021-09-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors.
J.Med.Chem., 64, 2021
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5ILS
 | | Autoinhibited ETV1 | | 分子名称: | ETS translocation variant 1 | | 著者 | Whitby, F.G, Currie, S.L. | | 登録日 | 2016-03-04 | | 公開日 | 2017-02-22 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | | 主引用文献 | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.
Nucleic Acids Res., 45, 2017
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5ILV
 | | Uninhibited ETV5 | | 分子名称: | ETS translocation variant 5 | | 著者 | Whitby, F.G, Currie, S.L. | | 登録日 | 2016-03-04 | | 公開日 | 2017-02-22 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.
Nucleic Acids Res., 45, 2017
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5ILU
 | | Autoinhibited ETV4 | | 分子名称: | ETS translocation variant 4 | | 著者 | Whitby, F.G, Currie, S.L. | | 登録日 | 2016-03-04 | | 公開日 | 2017-02-22 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.101 Å) | | 主引用文献 | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5.
Nucleic Acids Res., 45, 2017
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4V7O
 | | Proteasome Activator Complex | | 分子名称: | Proteasome activator BLM10, Proteasome component C1, Proteasome component C11, ... | | 著者 | Hill, C.P, Whitby, F.G. | | 登録日 | 2009-12-22 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | | 主引用文献 | Structure of a Blm10 complex reveals common mechanisms for proteasome binding and gate opening.
Mol.Cell, 37, 2010
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8UC6
 | | Calpain-7:IST1 Complex | | 分子名称: | Calpain-7, IST1 homolog | | 著者 | Paine, E, Whitby, F.G, Hill, C.P, Sunquist, W.I. | | 登録日 | 2023-09-25 | | 公開日 | 2023-10-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | | 主引用文献 | The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission.
Elife, 12, 2023
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2HTH
 | | Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain | | 分子名称: | Ubiquitin, Vacuolar protein sorting protein 36 | | 著者 | Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I. | | 登録日 | 2006-07-25 | | 公開日 | 2006-10-24 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain.
Nat.Struct.Mol.Biol., 13, 2006
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5VKO
 | | SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493 | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, ISOPROPYL ALCOHOL, Transcription elongation factor SPT6 | | 著者 | Sdano, M.A, Whitby, F.G, Hill, C.P. | | 登録日 | 2017-04-21 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.
Elife, 6, 2017
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5VKL
 | | SPT6 tSH2-RPB1 1476-1500 pS1493 | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, Transcription elongation factor SPT6 | | 著者 | Sdano, M.A, Whitby, F.G, Hill, C.P. | | 登録日 | 2017-04-21 | | 公開日 | 2017-10-25 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.198 Å) | | 主引用文献 | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.
Elife, 6, 2017
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6PSA
 | | PIE12 D-PEPTIDE AGAINST HIV ENTRY (IN COMPLEX WITH IQN17 Q577R RESISTANCE MUTANT) | | 分子名称: | CHLORIDE ION, IQN17, PIE12 D-peptide | | 著者 | Hill, C.P, Whitby, F.G, Kay, M, Weinstock, M. | | 登録日 | 2019-07-12 | | 公開日 | 2020-02-05 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Characterization of resistance to a potent D-peptide HIV entry inhibitor.
Retrovirology, 16, 2019
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4R0R
 | | Ebolavirus GP Prehairpin Intermediate Mimic | | 分子名称: | eboIZN21 | | 著者 | Clinton, T.R, Weinstock, M.T, Jacobsen, M.T, Szabo-Fresnais, N, Pandya, M.J, Whitby, F.G, Herbert, A.S, Prugar, L.I, McKinnon, R, Hill, C.P, Welch, B.D, Dye, J.M, Eckert, D.M, Kay, M.S. | | 登録日 | 2014-08-01 | | 公開日 | 2014-10-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets.
Protein Sci., 24, 2015
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7JX4
 | | Crystal Structure of N-Lysine Peptoid-modified Collagen Triple Helix | | 分子名称: | Collagen mimetic peptide with N-Lysine guest | | 著者 | Yu, M.S, Whitby, F.G, Hill, C.P, Kessler, J.L, Yang, L.D. | | 登録日 | 2020-08-26 | | 公開日 | 2021-07-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | Peptoid Residues Make Diverse, Hyperstable Collagen Triple-Helices.
J.Am.Chem.Soc., 143, 2021
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7JX5
 | | Crystal Structure of N-Phenylalanine Peptoid-modified Collagen Triple Helix | | 分子名称: | Collagen mimetic peptide with N-Phenylalanine guest | | 著者 | Yu, M.S, Whitby, F.G, Hill, C.P, Kessler, J.L, Yang, L.D. | | 登録日 | 2020-08-26 | | 公開日 | 2021-07-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Peptoid Residues Make Diverse, Hyperstable Collagen Triple-Helices
J.Am.Chem.Soc., 143, 2021
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7SMU
 | | Crystal Structure of Consomatin-Ro1 | | 分子名称: | 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxaoctatetracontane-1,48-diol, Consomatin-Ro1 | | 著者 | Ramiro, I.B.L, Whitby, F.G, Hill, C.P, Safavi-Hemami, H, Concepcion, G.P, Olivera, B.M. | | 登録日 | 2021-10-26 | | 公開日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Somatostatin venom analogs evolved by fish-hunting cone snails: From prey capture behavior to identifying drug leads.
Sci Adv, 8, 2022
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4LGM
 | | Crystal Structure of Sulfolobus solfataricus Vps4 | | 分子名称: | CHLORIDE ION, Vps4 AAA ATPase | | 著者 | Han, H, Hill, C.P, Whitby, F.G, Monroe, N. | | 登録日 | 2013-06-28 | | 公開日 | 2013-11-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.711 Å) | | 主引用文献 | The Oligomeric State of the Active Vps4 AAA ATPase.
J.Mol.Biol., 426, 2014
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