6NPF
 
 | | Structure of E.coli enolase in complex with an analog of the natural product SF-2312 metabolite. | | 分子名称: | Enolase, GLYCEROL, L(+)-TARTARIC ACID, ... | | 著者 | Erlandsen, H, Krucinska, J, Lombardo, M, Wright, D. | | 登録日 | 2019-01-17 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate.
Sci Rep, 9, 2019
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7MYM
 | | Crystal structure of Escherichia coli dihydrofolate reductase in complex with TRIMETHOPRIM and NADPH | | 分子名称: | ARGININE, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Erlandsen, H, Wright, D, Krucinska, J. | | 登録日 | 2021-05-21 | | 公開日 | 2022-06-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | | 主引用文献 | Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
Commun Biol, 5, 2022
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7NAE
 | | Crystal structure of Escherichia coli dihydrofolate reductase in complex with TRIMETHOPRIM | | 分子名称: | Dihydrofolate reductase, SULFATE ION, TRIMETHOPRIM | | 著者 | Estrada, A, Wright, D, Krucinska, J, Erlandsen, H. | | 登録日 | 2021-06-21 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
Commun Biol, 5, 2022
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6BFZ
 | | Crystal structure of enolase from E. coli with a mixture of apo form, substrate, and product form | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-PHOSPHOGLYCERIC ACID, Enolase, ... | | 著者 | Erlandsen, H, Wright, D, Krucinska, J. | | 登録日 | 2017-10-27 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
Biochemistry, 58, 2019
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6BFY
 | | Crystal structure of enolase from Escherichia coli with bound 2-phosphoglycerate substrate | | 分子名称: | 2-PHOSPHOGLYCERIC ACID, Enolase, GLYCEROL, ... | | 著者 | Erlandsen, H, Wright, D, Krucinska, J. | | 登録日 | 2017-10-27 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
Biochemistry, 58, 2019
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6D3Q
 | | Crystal structure of Escherichia coli enolase complexed with a natural inhibitor SF2312. | | 分子名称: | Enolase, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Erlandsen, H, Krucinska, J, Hazeen, A, Wright, D. | | 登録日 | 2018-04-16 | | 公開日 | 2019-11-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate.
Sci Rep, 9, 2019
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7R6G
 | | Crystal structure of DfrA5 dihydrofolate reductase in complex with TRIMETHOPRIM and NADPH | | 分子名称: | Dihydrofolate reductase type 5, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ... | | 著者 | Estrada, A, Wright, D, Krucinska, J, Erlandsen, H. | | 登録日 | 2021-06-22 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Structure-guided functional studies of plasmid-encoded dihydrofolate reductases reveal a common mechanism of trimethoprim resistance in Gram-negative pathogens.
Commun Biol, 5, 2022
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3Q51
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3Q50
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2P7F
 | | The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozyme | | 分子名称: | COBALT HEXAMMINE(III), Loop A ribozyme strand, Loop B S-turn strand, ... | | 著者 | Torelli, A.T, Krucinska, J, Wedekind, J.E. | | 登録日 | 2007-03-20 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization
Rna, 13, 2007
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2P7E
 | | Vanadate at the Active Site of a Small Ribozyme Suggests a Role for Water in Transition-State Stabilization | | 分子名称: | 3' substrate strand, octameric fragment, 5' substrate strand, ... | | 著者 | Torelli, A.T, Krucinska, J, Wedekind, J.E. | | 登録日 | 2007-03-20 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization
Rna, 13, 2007
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2P7D
 | | A Minimal, 'Hinged' Hairpin Ribozyme Construct Solved with Mimics of the Product Strands at 2.25 Angstroms Resolution | | 分子名称: | 3' substrate strand, octameric fragment, 5' substrate strand, ... | | 著者 | Torelli, A.T, Krucinska, J, Wedekind, J.E. | | 登録日 | 2007-03-20 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization
Rna, 13, 2007
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3CQS
 | | A 3'-OH, 2',5'-phosphodiester substitution in the hairpin ribozyme active site reveals similarities with protein ribonucleases | | 分子名称: | 13-mer substrate strand with 3'-OH, 2',5'-phosphodiester covalently linking 5th and 6th nucleotides, 19-mer ribozyme strand, ... | | 著者 | Torelli, A.T, Spitale, R.C, Krucinska, J, Wedekind, J.E. | | 登録日 | 2008-04-03 | | 公開日 | 2008-05-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Shared traits on the reaction coordinates of ribonuclease and an RNA enzyme
Biochem.Biophys.Res.Commun., 371, 2008
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4JCG
 | | Recombinant wild type Nitrosomonas europaea cytochrome c552 | | 分子名称: | Cytochrome c-552, HEME C | | 著者 | Wedekind, J.E, Can, M, Krucinska, J, Bren, K.L. | | 登録日 | 2013-02-21 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Structural Characterization of Nitrosomonas europaea Cytochrome c-552 Variants with Marked Differences in Electronic Structure.
Chembiochem, 14, 2013
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4G6R
 | | Minimal Hairpin Ribozyme in the Transition State with G8I Variation | | 分子名称: | Loop A Ribozyme strand, Loop A Substrate strand, Loop B Ribozyme Strand, ... | | 著者 | Liberman, J.A, Jenkins, J.L, Krucinska, J, Wedekind, J.E. | | 登録日 | 2012-07-19 | | 公開日 | 2012-08-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.832 Å) | | 主引用文献 | A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis.
J.Am.Chem.Soc., 134, 2012
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4G6P
 | | Minimal Hairpin Ribozyme in the Precatalytic State with A38P Variation | | 分子名称: | COBALT HEXAMMINE(III), Loop A Substrate strand, Loop A and Loop B Ribozyme strand, ... | | 著者 | Liberman, J.A, Jenkins, J.L, Krucinska, J, Wedekind, J.E. | | 登録日 | 2012-07-19 | | 公開日 | 2012-08-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.641 Å) | | 主引用文献 | A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis.
J.Am.Chem.Soc., 134, 2012
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4G6S
 | | Minimal Hairpin Ribozyme in the Transition State with A38P Variation | | 分子名称: | COBALT HEXAMMINE(III), Loop A Substrate strand, Loop A and Loop B Ribozyme strand, ... | | 著者 | Liberman, J.A, Jenkins, J.L, Krucinska, J, Wedekind, J.E. | | 登録日 | 2012-07-19 | | 公開日 | 2012-08-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | A Transition-State Interaction Shifts Nucleobase Ionization toward Neutrality To Facilitate Small Ribozyme Catalysis.
J.Am.Chem.Soc., 134, 2012
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3ZOW
 | | Crystal Structure of Wild Type Nitrosomonas europaea Cytochrome c552 | | 分子名称: | CYTOCHROME C-552, HEME C | | 著者 | Hersleth, H.-P, Can, M, Krucinska, J, Zoppellaro, G, Andersen, N.H, Karlsen, S, Wedekind, J.E, Andersson, K.K, Bren, K.L. | | 登録日 | 2013-02-25 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural Characterization of Nitrosomonas Europaea Cytochrome C-552 Variants with Marked Differences in Electronic Structure.
Chembiochem, 14, 2013
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3ZOY
 | | Crystal Structure of N64Del Mutant of Nitrosomonas europaea Cytochrome c552 (hexagonal space group) | | 分子名称: | CYTOCHROME C-552, HEME C | | 著者 | Hersleth, H.-P, Can, M, Krucinska, J, Zoppellaro, G, Andersen, N.H, Wedekind, J.E, Andersson, K.K, Bren, K.L. | | 登録日 | 2013-02-26 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Characterization of Nitrosomonas Europaea Cytochrome C-552 Variants with Marked Differences in Electronic Structure.
Chembiochem, 14, 2013
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3ZOX
 | | Crystal Structure of N64Del Mutant of Nitrosomonas europaea Cytochrome c552 (monoclinic space group) | | 分子名称: | CYTOCHROME C-552, HEME C | | 著者 | Hersleth, H.-P, Can, M, Krucinska, J, Zoppellaro, G, Andersen, N.H, Wedekind, J.E, Andersson, K.K, Bren, K.L. | | 登録日 | 2013-02-26 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Characterization of Nitrosomonas Europaea Cytochrome C-552 Variants with Marked Differences in Electronic Structure.
Chembiochem, 14, 2013
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1X9C
 | | An all-RNA Hairpin Ribozyme with mutation U39C | | 分子名称: | 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', ... | | 著者 | Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. | | 登録日 | 2004-08-20 | | 公開日 | 2005-11-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Conformational Heterogeneity at Position U37 of an All-RNA Hairpin Ribozyme with Implications for Metal Binding and the Catalytic Structure of the S-Turn.
Biochemistry, 44, 2005
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1X9K
 | | An all-RNA Hairpin Ribozyme with mutation U39C | | 分子名称: | 5'-R(*AP*AP*UP*AP*GP*AP*GP*AP*AP*GP*CP*GP*A)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*CP*AP*GP*UP*CP*CP*UP*AP*UP*U)-3', ... | | 著者 | Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. | | 登録日 | 2004-08-21 | | 公開日 | 2005-11-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Conformational Heterogeneity at Position U37 of an All-RNA Hairpin Ribozyme with Implications for Metal Binding and the Catalytic Structure of the S-Turn.
Biochemistry, 44, 2005
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2D2L
 | | Crystal Structure of a minimal, all-RNA hairpin ribozyme with a propyl linker (C3) at position U39 | | 分子名称: | 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', ... | | 著者 | Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. | | 登録日 | 2005-09-11 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn
Biochemistry, 44, 2005
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2D2K
 | | Crystal Structure of a minimal, native (U39) all-RNA hairpin ribozyme | | 分子名称: | 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', ... | | 著者 | Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. | | 登録日 | 2005-09-11 | | 公開日 | 2005-11-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Conformational heterogeneity at position U37 of an all-RNA hairpin ribozyme with implications for metal binding and the catalytic structure of the S-turn
Biochemistry, 44, 2005
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3B5F
 | | Crystal Structure of a Minimally Hinged Hairpin Ribozyme Incorporating the Ade38Dap Mutation and a 2',5' Phosphodiester Linkage at the Active Site | | 分子名称: | 29-mer Loop A and Loop B Ribozyme strand, COBALT HEXAMMINE(III), Loop A Substrate strand, ... | | 著者 | MacElrevey, C, Krucinska, J, Wedekind, J.E. | | 登録日 | 2007-10-25 | | 公開日 | 2008-08-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme.
Rna, 14, 2008
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