1FT8
 
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1W3B
 | | The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha. | | 分子名称: | CALCIUM ION, UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 | | 著者 | Jinek, M, Rehwinkel, J, Lazarus, B.D, Izaurralde, E, Hanover, J.A, Conti, E. | | 登録日 | 2004-07-14 | | 公開日 | 2004-09-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | The Superhelical Tpr-Repeat Domain of O-Linked Glcnac Transferase Exhibits Structural Similarities to Importin Alpha
Nat.Struct.Mol.Biol., 11, 2004
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5J3Y
 | | Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex | | 分子名称: | mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1 | | 著者 | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-03-31 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.288 Å) | | 主引用文献 | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
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5J3T
 | | Crystal structure of S. pombe Dcp2:Dcp1:Edc1 mRNA decapping complex | | 分子名称: | Edc1, FORMIC ACID, MAGNESIUM ION, ... | | 著者 | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-03-31 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
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1FO1
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5ONB
 | | Drosophila Bag-of-marbles CBM peptide bound to human CAF40 | | 分子名称: | CCR4-NOT transcription complex subunit 9, GLYCEROL, Protein bag-of-marbles | | 著者 | Raisch, T, Sgromo, A, Backhaus, C, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2017-08-03 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
RNA, 24, 2018
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1YA0
 | | Crystal structure of the N-terminal domain of human SMG7 | | 分子名称: | SMG-7 transcript variant 2, SULFATE ION | | 著者 | Fukuhara, N, Ebert, J, Unterholzner, L, Lindner, D, Izaurralde, E, Conti, E. | | 登録日 | 2004-12-17 | | 公開日 | 2005-03-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | SMG7 Is a 14-3-3-like Adaptor in the Nonsense-Mediated mRNA Decay Pathway.
Mol.Cell, 17, 2005
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1RK8
 | | Structure of the cytosolic protein PYM bound to the Mago-Y14 core of the exon junction complex | | 分子名称: | CALCIUM ION, CG8781-PA protein, Mago nashi protein, ... | | 著者 | Bono, F, Ebert, J, Guettler, T, Izaurralde, E, Conti, E. | | 登録日 | 2003-11-21 | | 公開日 | 2004-04-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular insights into the interaction of PYM with
the Mago-Y14 core of the exon junction complex
EMBO Rep., 5, 2004
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4GMJ
 | | Structure of human NOT1 MIF4G domain co-crystallized with CAF1 | | 分子名称: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ... | | 著者 | Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E. | | 登録日 | 2012-08-16 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
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4GML
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5FU7
 | | drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex | | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ... | | 著者 | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-01-21 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
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5FU6
 | | NOT module of the human CCR4-NOT complex (Crystallization mutant) | | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 | | 著者 | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-01-21 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
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5J3Q
 | | Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex | | 分子名称: | Edc1, mRNA-decapping enzyme subunit 1 | | 著者 | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-03-31 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
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2B9Z
 | | Solution structure of FHV B2, a viral suppressor of RNAi | | 分子名称: | B2 protein | | 著者 | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | | 登録日 | 2005-10-13 | | 公開日 | 2005-11-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.
Embo Rep., 6, 2005
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6HON
 | | Drosophila NOT4 CBM peptide bound to human CAF40 | | 分子名称: | CCR4-NOT transcription complex subunit 4, isoform L, CCR4-NOT transcription complex subunit 9, ... | | 著者 | Raisch, T, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
Genes Dev., 33, 2019
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6HOM
 | | Drosophila NOT4 CBM peptide bound to human CAF40 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CCR4-NOT transcription complex subunit 4, isoform L, ... | | 著者 | Raisch, T, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2018-09-17 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex.
Genes Dev., 33, 2019
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2HWX
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2HWW
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2HWY
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5T47
 | | Crystal structure of the D. melanogaster eIF4E-eIF4G complex | | 分子名称: | Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, isoform A, ... | | 著者 | Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. | | 登録日 | 2016-08-29 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
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5T46
 | | Crystal structure of the human eIF4E-eIF4G complex | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, ... | | 著者 | Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. | | 登録日 | 2016-08-29 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
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5T48
 | | Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, ... | | 著者 | Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. | | 登録日 | 2016-08-29 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
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1T2S
 | | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | | 分子名称: | 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2 | | 著者 | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | | 登録日 | 2004-04-22 | | 公開日 | 2004-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
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1T2R
 | | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | | 分子名称: | 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2 | | 著者 | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | | 登録日 | 2004-04-22 | | 公開日 | 2004-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain.
Nat.Struct.Mol.Biol., 11, 2004
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3RW7
 | | Structure of N-terminal domain of nuclear RNA export factor TAP | | 分子名称: | Nuclear RNA export factor 1 | | 著者 | Teplova, M, Khin, N.W, Wohlbold, L, Izaurralde, E, Patel, D.J. | | 登録日 | 2011-05-07 | | 公開日 | 2011-08-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP.
Nat.Struct.Mol.Biol., 18, 2011
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