4E2F
 
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8F7U
 | | Macrocyclic Plasmin Inhibitor | | 分子名称: | (5S,8R,18S,21R)-N-{[4-(aminomethyl)phenyl]methyl}-21-[(benzenesulfonyl)amino]-3,11,20-trioxo-2,5,8,12,19-pentaazatetracyclo[21.2.2.2~5,8~.2~13,16~]hentriaconta-1(25),13,15,23,26,28-hexaene-18-carboxamide, Activation peptide, GLYCEROL, ... | | 著者 | Guojie, W. | | 登録日 | 2022-11-20 | | 公開日 | 2023-02-08 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Synthesis and structural characterization of new macrocyclicplasmin inhibitors
Chemmedchem, 2023
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8F7V
 | | Macrocyclic plasmin inhibitor | | 分子名称: | (6S,9R,19S,22R)-N-{[4-(aminomethyl)phenyl]methyl}-22-[(benzenesulfonyl)amino]-3,12,21-trioxo-2,6,9,13,20-pentaazatetracyclo[22.2.2.2~6,9~.2~14,17~]dotriaconta-1(26),14,16,24,27,29-hexaene-19-carboxamide, GLYCEROL, Plasminogen, ... | | 著者 | Guojie, W. | | 登録日 | 2022-11-20 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-06-21 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Synthesis and structural characterization of new macrocyclicplasmin inhibitors
Chemmedchem, 2023
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7DXD
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7DXF
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7DXC
 | | Structure of TRPC3 at 3.06 angstrom in low calcium state | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL HEMISUCCINATE, Short transient receptor potential channel 3, ... | | 著者 | Chen, L, Guo, W. | | 登録日 | 2021-01-18 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
Neuron, 110, 2022
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7DXE
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7DXG
 | | Structure of SAR7334-bound TRPC6 at 2.9 angstrom | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[[(1R,2R)-2-[(3R)-3-azanylpiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloranyl-benzenecarbonitrile, CALCIUM ION, ... | | 著者 | Chen, L, Guo, W. | | 登録日 | 2021-01-18 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
Neuron, 110, 2022
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7DXB
 | | Structure of TRPC3 at 2.7 angstrom in high calcium state | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | | 著者 | Chen, L, Guo, W. | | 登録日 | 2021-01-18 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.
Neuron, 110, 2022
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4KH1
 | | The R state structure of E. coli ATCase with CTP,UTP, and Magnesium bound | | 分子名称: | Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R. | | 登録日 | 2013-04-29 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013
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4KGV
 | | The R state structure of E. coli ATCase with ATP bound | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ... | | 著者 | Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R. | | 登録日 | 2013-04-29 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013
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1CMI
 | | STRUCTURE OF THE HUMAN PIN/LC8 DIMER WITH A BOUND PEPTIDE | | 分子名称: | Dynein light chain 1, cytoplasmic, Nitric oxide synthase 1 | | 著者 | Liang, J, Guo, W, Jaffery, S, Snyder, S, Clardy, J. | | 登録日 | 1999-05-06 | | 公開日 | 2000-02-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the PIN/LC8 dimer with a bound peptide.
Nat.Struct.Biol., 6, 1999
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4KH0
 | | The R state structure of E. coli ATCase with ATP and Magnesium bound | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, ... | | 著者 | Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R. | | 登録日 | 2013-04-29 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013
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4KGZ
 | | The R state structure of E. coli ATCase with UTP and Magnesium bound | | 分子名称: | Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, MAGNESIUM ION, ... | | 著者 | Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R. | | 登録日 | 2013-04-29 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013
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4KGX
 | | The R state structure of E. coli ATCase with CTP bound | | 分子名称: | Aspartate carbamoyltransferase, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Cockrell, G.M, Zheng, Y, Guo, W, Peterson, A.W, Kantrowitz, E.R. | | 登録日 | 2013-04-29 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | New Paradigm for Allosteric Regulation of Escherichia coli Aspartate Transcarbamoylase.
Biochemistry, 52, 2013
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1NPP
 | | CRYSTAL STRUCTURE OF AQUIFEX AEOLICUS NUSG IN P2(1) | | 分子名称: | ISOPROPYL ALCOHOL, Transcription antitermination protein nusG | | 著者 | Knowlton, J.R, Bubunenko, M, Andrykovitch, M, Guo, W, Routzahn, K.M, Waugh, D.S, Court, D.L, Ji, X. | | 登録日 | 2003-01-18 | | 公開日 | 2003-03-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Spring-Loaded State of NusG in Its Functional Cycle Is Suggested by X-ray Crystallography and Supported by
Site-Directed Mutants
Biochemistry, 42, 2003
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1NPR
 | | CRYSTAL STRUCTURE OF AQUIFEX AEOLICUS NUSG IN C222(1) | | 分子名称: | Transcription antitermination protein nusG | | 著者 | Knowlton, J.R, Bubunenko, M, Andrykovitch, M, Guo, W, Routzhan, K.M, Waugh, D.S, Court, D.L, Ji, X. | | 登録日 | 2003-01-18 | | 公開日 | 2003-03-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | A Spring-Loaded State of NusG in Its Functional Cycle Is Suggested by X-ray Crystallography and Supported by
Site-Directed Mutants
Biochemistry, 42, 2003
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8GKO
 | | Crystal Structure Analysis of Aspergillus fumigatus alkaline protease | | 分子名称: | 1,2-ETHANEDIOL, Alkaline protease 1, FORMYL GROUP, ... | | 著者 | Fernandez, D, Diec, D.D.L, Guo, W, Russi, S. | | 登録日 | 2023-03-20 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | | 主引用文献 | Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision.
Sci Rep, 13, 2023
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8GKP
 | | Crystal Structure Analysis of Aspergillus fumigatus alkaline protease | | 分子名称: | Alkaline protease 1, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... | | 著者 | Fernandez, D, Diec, D.D.L, Guo, W, Russi, S. | | 登録日 | 2023-03-20 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision.
Sci Rep, 13, 2023
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8GKQ
 | | Crystal Structure Analysis of Aspergillus fumigatus alkaline protease | | 分子名称: | 1,2-ETHANEDIOL, Alkaline protease 1, CALCIUM ION, ... | | 著者 | Fernandez, D, Diec, D.D.L, Guo, W, Russi, S. | | 登録日 | 2023-03-20 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision.
Sci Rep, 13, 2023
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8U45
 | | Crystal Structure Analysis of Aspergillus fumigatus alkaline protease | | 分子名称: | Alkaline protease 1, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Fernandez, D, Diec, D.D.L, Guo, W, Russi, S. | | 登録日 | 2023-09-08 | | 公開日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Targeting Aspergillus allergen oryzin with a chemical probe at atomic precision.
Sci Rep, 13, 2023
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1EES
 | | SOLUTION STRUCTURE OF CDC42HS COMPLEXED WITH A PEPTIDE DERIVED FROM P-21 ACTIVATED KINASE, NMR, 20 STRUCTURES | | 分子名称: | GTP-BINDING PROTEIN, P21-ACTIVATED KINASE | | 著者 | Gizachew, D, Guo, W, Chohan, K.C, Sutcliffe, M.J, Oswald, R.E. | | 登録日 | 2000-02-02 | | 公開日 | 2000-03-29 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the complex of Cdc42Hs with a peptide derived from P-21 activated kinase.
Biochemistry, 39, 2000
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5YFP
 | | Cryo-EM Structure of the Exocyst Complex | | 分子名称: | Exocyst complex component EXO70, Exocyst complex component EXO84, Exocyst complex component SEC10, ... | | 著者 | Mei, K, Li, Y, Wang, S, Shao, G, Wang, J, Ding, Y, Luo, G, Yue, P, Liu, J.J, Wang, X, Dong, M.Q, Guo, W, Wang, H.W. | | 登録日 | 2017-09-21 | | 公開日 | 2018-01-31 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM structure of the exocyst complex
Nat. Struct. Mol. Biol., 25, 2018
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5ZBG
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5YX9
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