6QUJ
 
 | | GHK tagged GFP variant | | 分子名称: | COPPER (II) ION, GLYCEROL, Green fluorescent protein, ... | | 著者 | Huyton, T, Gorlich, D. | | 登録日 | 2019-02-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2022-12-07 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | The copper(II)-binding tripeptide GHK, a valuable crystallization and phasing tag for macromolecular crystallography.
Acta Crystallogr D Struct Biol, 76, 2020
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1QMA
 | | Nuclear Transport Factor 2 (NTF2) W7A mutant | | 分子名称: | NUCLEAR TRANSPORT FACTOR 2 | | 著者 | Bayliss, R, Ribbeck, K, Akin, D, Kent, H.M, Feldherr, C.M, Gorlich, D, Stewart, M.J. | | 登録日 | 1999-09-23 | | 公開日 | 2000-02-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Interaction Betweeen Ntf2 and Xfxfg-Containing Nucleoporins is Required to Mediate Nuclear Import of Ran-Gdp
J.Mol.Biol., 293, 1999
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1ZZP
 | | Solution structure of the F-actin binding domain of Bcr-Abl/c-Abl | | 分子名称: | Proto-oncogene tyrosine-protein kinase ABL1 | | 著者 | Hantschel, O, Wiesner, S, Guttler, T, Mackereth, C.D, Rix, L.L.R, Mikes, Z, Dehne, J, Gorlich, D, Sattler, M, Superti-Furga, G. | | 登録日 | 2005-06-14 | | 公開日 | 2005-08-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for the Cytoskeletal Association of Bcr-Abl/c-Abl.
Mol.Cell, 19, 2005
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8CDT
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8CDS
 | | Crystal structure of the xhNup93-Nb4i VHH antibody | | 分子名称: | 1,2-ETHANEDIOL, 5-Nup93 inhibitory VHH antibody, DI(HYDROXYETHYL)ETHER | | 著者 | Guttler, T, Colom, M.S, Gorlich, D. | | 登録日 | 2023-02-01 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | A checkpoint function for Nup98 in nuclear pore formation suggested by novel inhibitory nanobodies.
Embo J., 43, 2024
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6FVB
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8Q7S
 | | Crystal structure of the SARS-CoV-2 RBD (Wuhan) with neutralizing VHHs Ma6F06 and Re21H01 | | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, GLYCEROL, ... | | 著者 | Guttler, T, Aksu, M, Gorlich, D. | | 登録日 | 2023-08-16 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
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5MSE
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7OLZ
 | | Crystal structure of the SARS-CoV-2 RBD with neutralizing-VHHs Re5D06 and Re9F06 | | 分子名称: | 3-[BENZYL(DIMETHYL)AMMONIO]PROPANE-1-SULFONATE, Nanobody Re5D06, Nanobody Re9F06, ... | | 著者 | Aksu, M, Guttler, T, Gorlich, D. | | 登録日 | 2021-05-20 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies.
Embo J., 40, 2021
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7ON5
 | | Crystal structure of the SARS-CoV-2 neutralizing nanobody Re5D06 | | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, Nanobody Re5D06 | | 著者 | Aksu, M, Guttler, T, Gorlich, D. | | 登録日 | 2021-05-25 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodies.
Embo J., 40, 2021
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6NYR
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6NYS
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8Q94
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8Q93
 | | Crystal structure of the SARS-COV-2 RBD with neutralizing-VHHs Re30H02 and Re21D01 | | 分子名称: | Nanobody Re21D01, Nanobody Re30H02, Spike protein S1 | | 著者 | Aksu, M, Guttler, T, Rymarenko, O, Gorlich, D. | | 登録日 | 2023-08-19 | | 公開日 | 2023-12-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
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8Q95
 | | Crystal structure of the SARS-CoV-2 BA.1 RBD with neutralizing-VHHs Ma16B06 and Ma3F05 | | 分子名称: | Nanobody Ma16B06, Nanobody Ma3F05, Spike protein S1 | | 著者 | Aksu, M, Rymarenko, O, Guttler, T, Gorlich, D. | | 登録日 | 2023-08-19 | | 公開日 | 2023-12-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
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3NC1
 | | Crystal structure of the CRM1-RanGTP complex | | 分子名称: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | | 登録日 | 2010-06-04 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
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3NBY
 | | Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex | | 分子名称: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | | 登録日 | 2010-06-04 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
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3NC0
 | | Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal II) | | 分子名称: | DI(HYDROXYETHYL)ETHER, Exportin-1, GLYCEROL, ... | | 著者 | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | | 登録日 | 2010-06-04 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
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3NBZ
 | | Crystal structure of the HIV-1 Rev NES-CRM1-RanGTP nuclear export complex (crystal I) | | 分子名称: | Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. | | 登録日 | 2010-06-04 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1.
Nat.Struct.Mol.Biol., 17, 2010
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5DLQ
 | | Crystal structure of RanGTP-Exportin 4-eIF5A complex | | 分子名称: | Eukaryotic translation initiation factor 5A-1, Exportin-4, GTP-binding nuclear protein Ran, ... | | 著者 | Aksu, M, Trakhanov, S, Gorlich, D. | | 登録日 | 2015-09-07 | | 公開日 | 2016-06-22 | | 最終更新日 | 2016-06-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structure of the exportin Xpo4 in complex with RanGTP and the hypusine-containing translation factor eIF5A.
Nat Commun, 7, 2016
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5C3L
 | | Structure of the metazoan Nup62.Nup58.Nup54 nucleoporin complex. | | 分子名称: | Nanobody Nb15, Nucleoporin Nup58, Nucleoporin Nup62, ... | | 著者 | Chug, H, Trakhanov, S, Hulsmann, B.B, Pleiner, T, Gorlich, D. | | 登録日 | 2015-06-17 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the metazoan Nup62Nup58Nup54 nucleoporin complex.
Science, 350, 2015
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5C2U
 | | Ferredoxin-like domain of nucleoporin Nup54 bound to a nanobody | | 分子名称: | Nanobody, Nup54 | | 著者 | Chug, H, Trakhanov, S, Hulsmann, B.B, Pleiner, T, Gorlich, D. | | 登録日 | 2015-06-16 | | 公開日 | 2015-08-26 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of the metazoan Nup62Nup58Nup54 nucleoporin complex.
Science, 350, 2015
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6Q84
 | | Crystal structure of RanGTP-Pdr6-eIF5A export complex | | 分子名称: | Eukaryotic translation initiation factor 5A-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D. | | 登録日 | 2018-12-14 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
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6Q83
 | | Crystal structure of the biportin Pdr6 in complex with UBC9 | | 分子名称: | Importin beta-like protein KAP122, UBC9 | | 著者 | Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D. | | 登録日 | 2018-12-14 | | 公開日 | 2019-05-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (4.53 Å) | | 主引用文献 | Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
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6Q82
 | | Crystal structure of the biportin Pdr6 in complex with RanGTP | | 分子名称: | GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin beta-like protein KAP122, ... | | 著者 | Aksu, M, Vera-Rodriguez, A, Trakhanov, S, Gorlich, D. | | 登録日 | 2018-12-14 | | 公開日 | 2019-05-01 | | 最終更新日 | 2019-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.994 Å) | | 主引用文献 | Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
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