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1T7P
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BU of 1t7p by Molmil
T7 DNA POLYMERASE COMPLEXED TO DNA PRIMER/TEMPLATE,A NUCLEOSIDE TRIPHOSPHATE, AND ITS PROCESSIVITY FACTOR THIOREDOXIN
分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*CP*TP*TP*GP*GP*CP*AP*CP*TP*GP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*2DA)-3'), ...
著者Doublie, S, Tabor, S, Long, A.M, Richardson, C.C, Ellenberger, T.
登録日1997-09-24
公開日1998-02-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution.
Nature, 391, 1998
1TDH
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BU of 1tdh by Molmil
Crystal structure of human endonuclease VIII-like 1 (NEIL1)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, nei endonuclease VIII-like 1
著者Doublie, S, Bandaru, V, Bond, J.P, Wallace, S.S.
登録日2004-05-22
公開日2004-07-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity.
Proc.Natl.Acad.Sci.USA, 101, 2004
4KGK
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BU of 4kgk by Molmil
Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein in complex with GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Thg1-like uncharacterized protein
著者Hyde, S.J, Rao, B.S, Eckenroth, B.E, Jackman, J.E, Doublie, S.
登録日2013-04-29
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Studies of a Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein, with Nucleotide in the Activation and Nucleotidyl Transfer Sites.
Plos One, 8, 2013
4X0P
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BU of 4x0p by Molmil
Ternary complex of human DNA polymerase theta C-terminal domain binding ddATP opposite a tetrahydrofuran AP site analog
分子名称: 2',3'-dideoxyadenosine triphosphate, CALCIUM ION, DNA (5'-D(*CP*GP*TP*TP*GP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), ...
著者Zahn, K.E, Doublie, S.
登録日2014-11-21
公開日2015-03-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.911 Å)
主引用文献Human DNA polymerase theta grasps the primer terminus to mediate DNA repair.
Nat.Struct.Mol.Biol., 22, 2015
4X0Q
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BU of 4x0q by Molmil
Ternary complex of human DNA polymerase theta C-terminal domain binding ddGTP opposite dCMP
分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*CP*CP*AP*AP*TP*GP*AP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*TP*CP*AP*TP*TP*G)-3'), ...
著者Zahn, K.E, Doublie, S.
登録日2014-11-22
公開日2015-03-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Human DNA polymerase theta grasps the primer terminus to mediate DNA repair.
Nat.Struct.Mol.Biol., 22, 2015
6MW4
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BU of 6mw4 by Molmil
Structure of pseudoprotease CspC from Clostridioides difficile
分子名称: Putative germination-specific protease, SULFATE ION
著者Eckenroth, B.E, Doublie, S.
登録日2018-10-29
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The CspC pseudoprotease regulates germination of Clostridioides difficile spores in response to multiple environmental signals.
Plos Genet., 15, 2019
8SYJ
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BU of 8syj by Molmil
Structure of apurinic/apyrimidinic DNA lyase TK0353 from Thermococcus kodakarensis (Iodide crystal form)
分子名称: GLYCEROL, IODIDE ION, SULFATE ION, ...
著者Eckenroth, B.E, Gardner, A.F, Doublie, S.
登録日2023-05-25
公開日2023-12-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Thermococcus kodakarensis TK0353 is a novel AP lyase with a new fold.
J.Biol.Chem., 300, 2023
8TH9
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Structure of mammalian NEIL2 from Monodelphis domestica in complex with THF-containing DNA
分子名称: DIMETHYL SULFOXIDE, DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), ...
著者Eckenroth, B.E, Doublie, S.
登録日2023-07-14
公開日2023-11-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structural and biochemical insights into NEIL2's preference for abasic sites.
Nucleic Acids Res., 51, 2023
3VK8
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BU of 3vk8 by Molmil
Crystal structure of DNA-glycosylase bound to DNA containing Thymine glycol
分子名称: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(CTG)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), GLYCEROL, ...
著者Imamura, K, Averill, A, Wallace, S.S, Doublie, S.
登録日2011-11-10
公開日2011-12-14
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural characterization of viral ortholog of human DNA glycosylase NEIL1 bound to thymine glycol or 5-hydroxyuracil-containing DNA
J.Biol.Chem., 287, 2012
3VK7
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BU of 3vk7 by Molmil
Crystal structure of DNA-glycosylase bound to DNA containing 5-Hydroxyuracil
分子名称: DNA (5'-D(*CP*GP*TP*CP*CP*AP*(OHU)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*GP*AP*CP*GP*TP*GP*GP*AP*CP*G)-3'), FORMIC ACID, ...
著者Imamura, K, Averill, A, Wallace, S.S, Doublie, S.
登録日2011-11-10
公開日2011-12-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural characterization of viral ortholog of human DNA glycosylase NEIL1 bound to thymine glycol or 5-hydroxyuracil-containing DNA
J.Biol.Chem., 287, 2012
8GM7
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BU of 8gm7 by Molmil
Structure of apurinic/apyrimidinic DNA Lyase TK0353 from Thermococcus kodakarensis (Native Crystal Form)
分子名称: GLYCEROL, SULFATE ION, TK0353
著者Eckenroth, B.E, Gardner, A.F, Doublie, S.
登録日2023-03-24
公開日2023-12-06
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Thermococcus kodakarensis TK0353 is a novel AP lyase with a new fold.
J.Biol.Chem., 300, 2023
8GM6
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BU of 8gm6 by Molmil
Structure of apurinic/apyrimidinic DNA lyase TK0353 from Thermococcus kodakarensis (Selenomethionine)
分子名称: GLYCEROL, SULFATE ION, TK0353
著者Eckenroth, B.E, Gardner, A.F, Doublie, S.
登録日2023-03-24
公開日2023-12-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Thermococcus kodakarensis TK0353 is a novel AP lyase with a new fold.
J.Biol.Chem., 300, 2023
4PPX
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BU of 4ppx by Molmil
DNA Polymerase Beta E295K with Spiroiminodihydantoin in Templating Position
分子名称: 5'-D(*CP*CP*GP*AP*CP*(SDH)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*G)-3', ...
著者Eckenroth, B.E, Doublie, S.
登録日2014-02-27
公開日2014-04-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal Structure of DNA Polymerase beta with DNA Containing the Base Lesion Spiroiminodihydantoin in a Templating Position.
Biochemistry, 53, 2014
1SL2
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BU of 1sl2 by Molmil
Ternary 5' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template and an incoming nucleotide
分子名称: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*TP*(2DA))-3', ...
著者Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T.
登録日2004-03-05
公開日2004-07-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Nat.Struct.Mol.Biol., 11, 2004
1SKW
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BU of 1skw by Molmil
Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template
分子名称: 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', DNA polymerase, ...
著者Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T.
登録日2004-03-05
公開日2004-07-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Nat.Struct.Mol.Biol., 11, 2004
1SKS
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BU of 1sks by Molmil
Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template
分子名称: 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', DNA polymerase, ...
著者Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T.
登録日2004-03-05
公開日2004-07-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Nat.Struct.Mol.Biol., 11, 2004
1SL1
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BU of 1sl1 by Molmil
Binary 5' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template
分子名称: 5'-D(*CP*CP*C*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*TP*(2DA))-3', DNA polymerase, ...
著者Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T.
登録日2004-03-05
公開日2004-07-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Nat.Struct.Mol.Biol., 11, 2004
1SKR
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BU of 1skr by Molmil
T7 DNA Polymerase Complexed To DNA Primer/Template and ddATP
分子名称: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*CP*TP*TP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(2DA))-3', ...
著者Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T.
登録日2004-03-05
公開日2004-07-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Nat.Struct.Mol.Biol., 11, 2004
6VJI
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BU of 6vji by Molmil
Structure of mammalian NEIL2 from Monodelphis domestica
分子名称: Nei like DNA glycosylase 2, ZINC ION
著者Eckenroth, B.E, Doublie, S.
登録日2020-01-16
公開日2020-08-12
最終更新日2021-01-20
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Unique Structural Features of Mammalian NEIL2 DNA Glycosylase Prime Its Activity for Diverse DNA Substrates and Environments.
Structure, 29, 2021
4I0W
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BU of 4i0w by Molmil
Structure of the Clostridium Perfringens CspB protease
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Protease CspB, ...
著者Adams, C.M, Eckenroth, B.E, Doublie, S.
登録日2012-11-19
公開日2013-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and functional analysis of the CspB protease required for Clostridium spore germination.
Plos Pathog., 9, 2013
4KGM
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BU of 4kgm by Molmil
Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Hyde, S.J, Rao, B.S, Eckenroth, B.E, Jackman, J.E, Doublie, S.
登録日2013-04-29
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.361 Å)
主引用文献Structural Studies of a Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein, with Nucleotide in the Activation and Nucleotidyl Transfer Sites.
Plos One, 8, 2013
6BTE
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BU of 6bte by Molmil
DNA Polymerase Beta I260Q Binary Complex
分子名称: CHLORIDE ION, DNA Downstream Strand, DNA Primer Strand, ...
著者Eckenroth, B.E, Doublie, S.
登録日2017-12-06
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity.
Nucleic Acids Res., 46, 2018
6BTF
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BU of 6btf by Molmil
DNA Polymerase Beta I260Q Ternary Complex
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA Downstream Strand, DNA Primer Strand, ...
著者Eckenroth, B.E, Doublie, S.
登録日2017-12-06
公開日2018-09-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity.
Nucleic Acids Res., 46, 2018
7RAG
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BU of 7rag by Molmil
Structure of the CwlD amidase from Clostridioides difficile in complex with the GerS lipoprotein
分子名称: 1,2-ETHANEDIOL, Germination-specific N-acetylmuramoyl-L-alanine amidase, Autolysin, ...
著者Eckenroth, B.E, Doublie, S.
登録日2021-07-01
公開日2021-09-08
最終更新日2021-10-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A lipoprotein allosterically activates the CwlD amidase during Clostridioides difficile spore formation.
Plos Genet., 17, 2021
7RDS
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BU of 7rds by Molmil
Structure of human NTHL1
分子名称: IRON/SULFUR CLUSTER, Isoform 3 of Endonuclease III-like protein 1
著者Carroll, B.L, Zahn, K.E, Doublie, S.
登録日2021-07-11
公開日2021-12-29
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysis.
Nucleic Acids Res., 49, 2021

 

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