1YZZ
| Humanized caban33 at room temperature | 分子名称: | anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | 著者 | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Decanniere, K, Muyldermans, S, Loris, R. | 登録日 | 2005-03-01 | 公開日 | 2005-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Antigen binding and solubility effects upon the veneering of a camel VHH in framework-2 to mimic a VH. J.Mol.Biol., 350, 2005
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1YC7
| cAbAn33 VHH fragment against VSG | 分子名称: | SULFATE ION, anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | 著者 | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R. | 登録日 | 2004-12-22 | 公開日 | 2005-06-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH. J.Mol.Biol., 350, 2005
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1YC8
| cAbAn33- Y37V/E44G/R45L triple mutant | 分子名称: | anti-VSG immunoglobulin heavy chain variable domain cAbAn33 | 著者 | Conrath, K, Vincke, C, Stijlemans, B, Schymkowitz, J, Wyns, L, Muyldermans, S, Loris, R. | 登録日 | 2004-12-22 | 公開日 | 2005-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Antigen Binding and Solubility Effects upon the Veneering of a Camel VHH in Framework-2 to Mimic a VH. J.Mol.Biol., 350, 2005
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3EAK
| NbBCII10 humanized (FGLA mutant) | 分子名称: | NbBCII10-FGLA, SULFATE ION | 著者 | Vincke, C, Loris, R, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K. | 登録日 | 2008-08-26 | 公開日 | 2008-12-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | General strategy to humanize a camelid single-domain antibody and identification of a universal humanized nanobody scaffold. J.Biol.Chem., 2008
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3DWT
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3EBA
| CAbHul6 FGLW mutant (humanized) in complex with human lysozyme | 分子名称: | CAbHul6, Lysozyme C, SULFATE ION | 著者 | Loris, R, Vincke, C, Saerens, D, Martinez-Rodriguez, S, Muyldermans, S, Conrath, K. | 登録日 | 2008-08-27 | 公開日 | 2008-12-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold J.Biol.Chem., 284, 2009
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1ZVH
| Crystal structure of the VHH domain D2-L24 in complex with hen egg white lysozyme | 分子名称: | Immunoglobulin heavy chain antibody variable domain, Lysozyme C | 著者 | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | 登録日 | 2005-06-02 | 公開日 | 2006-04-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZV5
| Crystal structure of the variable domain of the camelid heavy-chain antibody D2-L29 in complex with hen egg white lysozyme | 分子名称: | Lysozyme C, PHOSPHATE ION, immunoglobulin heavy chain antibody variable domain | 著者 | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | 登録日 | 2005-06-01 | 公開日 | 2006-04-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZVY
| Crystal structure of the VHH D3-L11 in complex with hen egg white lysozyme | 分子名称: | GLYCEROL, Immunoglobulin heavy chain antibody variable domain, Lysozyme C, ... | 著者 | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | 登録日 | 2005-06-03 | 公開日 | 2006-04-04 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZMY
| cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme | 分子名称: | Antibody cabbcII-10:lys3, Lysozyme C | 著者 | Saerens, D, Pellis, M, Loris, R, Pardon, E, Dumoulin, M, Matagne, A, Wyns, L, Muyldermans, S, Conrath, K. | 登録日 | 2005-05-11 | 公開日 | 2005-10-04 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies J.Mol.Biol., 352, 2005
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5M7M
| Novel Imidazo[1,2-a]pyridine Derivatives with Potent Autotaxin/ENPP2 Inhibitor Activity | 分子名称: | CHLORIDE ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, IODIDE ION, ... | 著者 | Wolhkoning, A, Fleury, D, Leonard, P, Triballeau, N, Mollat, P, Vercheval, L. | 登録日 | 2016-10-28 | 公開日 | 2017-08-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors. J. Med. Chem., 60, 2017
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