1MD8
| Monomeric structure of the active catalytic domain of complement protease C1r | 分子名称: | C1R COMPLEMENT SERINE PROTEASE | 著者 | Budayova-Spano, M, Grabarse, W, Thielens, N.M, Hillen, H, Lacroix, M, Schmidt, M, Fontecilla-Camps, J, Arlaud, G.J, Gaboriaud, C. | 登録日 | 2002-08-07 | 公開日 | 2003-08-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism Structure, 10, 2002
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1MD7
| Monomeric structure of the zymogen of complement protease C1r | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C1R COMPLEMENT SERINE PROTEASE | 著者 | Budayova-Spano, M, Grabarse, W, Thielens, N.M, Hillen, H, Lacroix, M, Schmidt, M, Fontecilla-Camps, J, Arlaud, G.J, Gaboriaud, C. | 登録日 | 2002-08-07 | 公開日 | 2003-08-07 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Monomeric structures of the zymogen and active catalytic domain of complement protease c1r: further insights into the c1 activation mechanism Structure, 10, 2002
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1SZB
| Crystal structure of the human MBL-associated protein 19 (MAp19) | 分子名称: | CALCIUM ION, mannose binding lectin-associated serine protease-2 related protein, MAp19 (19kDa) | 著者 | Gregory, L.A, Thielens, N.M, Arlaud, G.J, Fontecilla-Camps, J.C, Gaboriaud, C. | 登録日 | 2004-04-05 | 公開日 | 2004-06-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The X-ray structure of human MBL-associated protein 19 (MAp19) and its interaction site with mannan-binding lectin and L-ficolin J.Biol.Chem., 279, 2004
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3POS
| Crystal structure of the globular domain of human calreticulin | 分子名称: | CALCIUM ION, Calreticulin | 著者 | Chouquet, A, Paidassi, H, Ling, W.-L, Frachet, P, Houen, G, Arlaud, G.J, Gaboriaud, C. | 登録日 | 2010-11-23 | 公開日 | 2011-03-09 | 最終更新日 | 2017-08-09 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | X-ray structure of the human calreticulin globular domain reveals a Peptide-binding area and suggests a multi-molecular mechanism Plos One, 6, 2011
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1APQ
| STRUCTURE OF THE EGF-LIKE MODULE OF HUMAN C1R, NMR, 19 STRUCTURES | 分子名称: | COMPLEMENT PROTEASE C1R | 著者 | Bersch, B, Hernandez, J.-F, Marion, D, Arlaud, G.J. | 登録日 | 1997-07-22 | 公開日 | 1997-09-17 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the epidermal growth factor (EGF)-like module of human complement protease C1r, an atypical member of the EGF family. Biochemistry, 37, 1998
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1PK6
| Globular Head of the Complement System Protein C1q | 分子名称: | CALCIUM ION, Complement C1q subcomponent, A chain precursor, ... | 著者 | Gaboriaud, C, Juanhuix, J, Gruez, A, Lacroix, M, Darnault, C, Pignol, D, Verger, D, Fontecilla-Camps, J.C, Arlaud, G.J. | 登録日 | 2003-06-05 | 公開日 | 2003-10-21 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties. J.Biol.Chem., 278, 2003
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1NZI
| Crystal Structure of the CUB1-EGF Interaction Domain of Complement Protease C1s | 分子名称: | CALCIUM ION, Complement C1s component, MAGNESIUM ION | 著者 | Gregory, L.A, Thielens, N.M, Arlaud, G.J, Fontecilla-Camps, J.C, Gaboriaud, C. | 登録日 | 2003-02-18 | 公開日 | 2003-06-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement J.Biol.Chem., 278, 2003
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2WNU
| Complex between c1q globular heads and heparan sulfate | 分子名称: | 2-O-sulfo-beta-L-altropyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A, ... | 著者 | Garlatti, V, Chouquet, A, Lunardi, T, Thielens, N.M, Arlaud, G.J, Gaboriaud, C. | 登録日 | 2009-07-20 | 公開日 | 2010-05-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cutting Edge: C1Q Binds Deoxyribose and Heparan Sulfate Through Neighboring Sites of its Recognition Domain. J.Immunol., 185, 2010
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2WNV
| Complex between C1q globular heads and deoxyribose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-beta-D-erythro-pentofuranose, CALCIUM ION, ... | 著者 | Garlatti, V, Chouquet, A, Lunardi, T, Thielens, N.M, Arlaud, G.J, Gaboriaud, C. | 登録日 | 2009-07-20 | 公開日 | 2010-05-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Cutting Edge: C1Q Binds Deoxyribose and Heparan Sulfate Through Neighboring Sites of its Recognition Domain. J.Immunol., 185, 2010
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2WNP
| M-ficolin mutant Y271F | 分子名称: | CALCIUM ION, FICOLIN-1, ISOPROPYL ALCOHOL | 著者 | Gout, E, Garlatti, V, Smith, D.F, Lacroix, M, Dumestre-Perard, C, Lunardi, T, Arlaud, G.J, Gaboriaud, C, Thielens, N.M. | 登録日 | 2009-07-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Carbohydrate Recognition Properties of Human Ficolins: Glycan Array Screening Reveals the Sialic Acid Binding Specificity of M-Ficolin. J.Biol.Chem., 285, 2010
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2JHL
| Structure of globular heads of M-ficolin complexed with sialic acid | 分子名称: | CALCIUM ION, FICOLIN-1, N-acetyl-beta-neuraminic acid | 著者 | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | 登録日 | 2007-02-22 | 公開日 | 2007-10-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch. J.Biol.Chem., 282, 2007
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2JHK
| Structure of globular heads of M-ficolin complexed with N-acetyl-D- glucosamine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FICOLIN-1 | 著者 | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | 登録日 | 2007-02-22 | 公開日 | 2007-10-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch. J.Biol.Chem., 282, 2007
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2JHH
| Structure of globular heads of M-ficolin at acidic pH | 分子名称: | CALCIUM ION, FICOLIN-1 | 著者 | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | 登録日 | 2007-02-22 | 公開日 | 2007-10-09 | 最終更新日 | 2019-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch. J. Biol. Chem., 282, 2007
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2JHI
| Structure of globular heads of M-ficolin complexed with N-acetyl-D- galactosamine | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, FICOLIN-1 | 著者 | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | 登録日 | 2007-02-22 | 公開日 | 2007-10-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch. J.Biol.Chem., 282, 2007
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2JHM
| Structure of globular heads of M-ficolin at neutral pH | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, FICOLIN-1, ... | 著者 | Garlatti, V, Martin, L, Gout, E, Reiser, J.B, Arlaud, G.J, Thielens, N.M, Gaboriaud, C. | 登録日 | 2007-02-22 | 公開日 | 2007-10-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Structural Basis for Innate Immune Sensing by M-Ficolin and its Control by a Ph-Dependent Conformational Switch. J.Biol.Chem., 282, 2007
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2JG8
| Crystallographic structure of human C1q globular heads complexed to phosphatidyl-serine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C1q subcomponent subunit A, ... | 著者 | Paidassi, H, Tacnet-Delorme, P, Garlatti, V, Darnault, C, Ghebrehiwet, B, Gaboriaud, C, Arlaud, G.J, Frachet, P. | 登録日 | 2007-02-09 | 公開日 | 2008-02-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition. J.Immunol., 180, 2008
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2JG9
| Crystallographic structure of human C1q globular heads (P1) | 分子名称: | CALCIUM ION, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, ... | 著者 | Paidassi, H, Tacnet-Delorme, P, Garlatti, V, Darnault, C, Ghebrehiwet, B, Gaboriaud, C, Arlaud, G.J, Frachet, P. | 登録日 | 2007-02-09 | 公開日 | 2008-02-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | C1Q Binds Phosphatidylserine and Likely Acts as a Multiligand-Bridging Molecule in Apoptotic Cell Recognition. J.Immunol., 180, 2008
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3DEM
| CUB1-EGF-CUB2 domain of HUMAN MASP-1/3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement factor MASP-3 | 著者 | Gaboriaud, C. | 登録日 | 2008-06-10 | 公開日 | 2008-07-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins J.Biol.Chem., 283, 2008
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4IW4
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1ELV
| CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN COMPLEMENT C1S PROTEASE | 分子名称: | 2-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C1S COMPONENT, ... | 著者 | Gaboriaud, C, Rossi, V, Bally, I, Arlaud, G, Fontecilla-Camps, J.-C. | 登録日 | 2000-03-14 | 公開日 | 2001-03-14 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle. EMBO J., 19, 2000
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3POW
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1FCT
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5LK5
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2J64
| H-ficolin | 分子名称: | CALCIUM ION, FICOLIN-3 | 著者 | Garlatti, V, Gaboriaud, C. | 登録日 | 2006-09-25 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins. Embo J., 26, 2007
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2J3U
| L-ficolin complexed to galactose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Garlatti, V, Gaboriaud, C. | 登録日 | 2006-08-23 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins. Embo J., 26, 2007
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