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5YIM
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BU of 5yim by Molmil
Structure of a Legionella effector
分子名称: SdeA
著者Feng, Y, Dong, Y, Wang, W.
登録日2017-10-05
公開日2018-05-30
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.394 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
7W0Q
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BU of 7w0q by Molmil
TRIM7 in complex with C-terminal peptide of 2C
分子名称: E3 ubiquitin-protein ligase TRIM7, peptide
著者Zhang, H, Liang, X, Li, X.Z.
登録日2021-11-18
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
7W0T
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BU of 7w0t by Molmil
TRIM7 in complex with C-terminal peptide of 2C
分子名称: E3 ubiquitin-protein ligase TRIM7, peptide
著者Zhang, H, Liang, X, Li, X.Z.
登録日2021-11-18
公開日2022-08-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
Nat.Chem.Biol., 18, 2022
6JNY
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BU of 6jny by Molmil
Crystal structure of bacteriophage 21 Q protein
分子名称: Antiterminator Q protein
著者Feng, Y, Shi, J.
登録日2019-03-18
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structural basis of Q-dependent transcription antitermination.
Nat Commun, 10, 2019
8IZL
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BU of 8izl by Molmil
Structure of the Mumps Virus L Protein Bound by Phosphoprotein Tetramer
分子名称: Phosphoprotein, RNA-directed RNA polymerase L, ZINC ION
著者Li, T.H, Shen, Q.T.
登録日2023-04-07
公開日2024-04-17
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structures of the mumps virus polymerase complex via cryo-electron microscopy.
Nat Commun, 15, 2024
7SXI
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BU of 7sxi by Molmil
Solution Structure of Sds3 Capped Tudor Domain
分子名称: Sin3 histone deacetylase corepressor complex component SDS3
著者Marcum, R.D, Radhakrishnan, I.
登録日2021-11-23
公開日2022-01-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A capped Tudor domain within a core subunit of the Sin3L/Rpd3L histone deacetylase complex binds to nucleic acid G-quadruplexes.
J.Biol.Chem., 298, 2022
5YIK
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BU of 5yik by Molmil
Structure of a Legionella effector with its substrate
分子名称: SdeA, ubiquitin
著者Feng, Y, Dong, Y, Liu, Z.
登録日2017-10-05
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
8JBV
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BU of 8jbv by Molmil
Extracellular domain of gamma delta TCR
分子名称: T cell receptor delta variable 1,T cell receptor delta constant, T cell receptor gamma variable 5,T cell receptor gamma constant 1
著者Xin, W, Chi, X, Huang, B, Su, Q, Zhou, Q.
登録日2023-05-09
公開日2024-05-08
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Structures of human gamma delta T cell receptor-CD3 complex.
Nature, 630, 2024
3F9H
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BU of 3f9h by Molmil
Crystal Structure of the F140A mutant of SARS-Coronovirus 3C-like Protease at pH 7.6
分子名称: 3C-like proteinase
著者Hu, T, Li, L, Jiang, H, Shen, X.
登録日2008-11-13
公開日2009-09-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure.
Virology, 388, 2009
4CYZ
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BU of 4cyz by Molmil
Structure of the A_mallard_Sweden_51_2002 H10 Avian Haemmaglutinin in complex with avian receptor analog LSTA
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Vachieri, S.G, Xiong, X, Collins, P.J, Walker, P.A, Martin, S.R, Haire, L.F, McCauley, J.W, Gamblin, S.J, Skehel, J.J.
登録日2014-04-16
公開日2014-06-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Receptor Binding by H10 Influenza Viruses.
Nature, 511, 2014
7F83
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BU of 7f83 by Molmil
Crystal Structure of a receptor in Complex with inverse agonist
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone, Growth hormone secretagogue receptor type 1,Soluble cytochrome b562
著者Xu, Z, Shao, Z.
登録日2021-07-01
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Molecular mechanism of agonism and inverse agonism in ghrelin receptor.
Nat Commun, 13, 2022
4DXL
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BU of 4dxl by Molmil
Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abscessus, bound to CMP and ATP
分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-02-27
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4DQ8
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BU of 4dq8 by Molmil
Crystal structure of acetate kinase AckA from Mycobacterium marinum
分子名称: Acetate kinase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-02-15
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
5YIJ
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BU of 5yij by Molmil
Structure of a Legionella effector with substrates
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, SdeA, Ubiquitin
著者Feng, Y, Mu, Y, Wang, H.
登録日2017-10-05
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
8JV5
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BU of 8jv5 by Molmil
Cryo-EM structure of the zebrafish P2X4 receptor in complex with BX430
分子名称: 1-[2,6-bis(bromanyl)-4-propan-2-yl-phenyl]-3-pyridin-3-yl-urea, 2-acetamido-2-deoxy-beta-D-glucopyranose, P2X purinoceptor
著者Hattori, M, Shen, C.
登録日2023-06-27
公開日2023-10-18
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural insights into the allosteric inhibition of P2X4 receptors.
Nat Commun, 14, 2023
8JV6
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BU of 8jv6 by Molmil
Cryo-EM structure of the zebrafish P2X4 receptor in complex with BAY-1797
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[4-(3-chloranylphenoxy)-3-sulfamoyl-phenyl]-2-phenyl-ethanamide, P2X purinoceptor
著者Hattori, M, Shen, C.
登録日2023-06-27
公開日2023-10-18
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献Structural insights into the allosteric inhibition of P2X4 receptors.
Nat Commun, 14, 2023
7XDK
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BU of 7xdk by Molmil
Cryo-EM structure of SARS-CoV-2 Delta Spike protein in complex with BA7054 and BA7125 fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7054 fab, ...
著者Liu, Z, Lui, S, Gao, Y.
登録日2022-03-27
公開日2023-03-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5.
Cell Discov, 9, 2023
4YGY
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BU of 4ygy by Molmil
Crystal Structure of Human Scp1 bound to trans-proline peptidomimetic CTD phospho-Ser5 peptide
分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, peptidomimetic CTD phospho-Ser5 peptide
著者Mayfield, J.E, Zhang, Y.
登録日2015-02-26
公開日2015-09-16
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II.
Acs Chem.Biol., 10, 2015
7F9I
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BU of 7f9i by Molmil
The apo-form structure of EnrR
分子名称: EnrR repressor
著者Gan, J.H, Wang, Q.Y.
登録日2021-07-04
公開日2022-05-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Xenogeneic nucleoid-associated EnrR thwarts H-NS silencing of bacterial virulence with unique DNA binding.
Nucleic Acids Res., 50, 2022
7F9H
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BU of 7f9h by Molmil
complex structure of EnrR-DNA
分子名称: EnrR repressor, target DNA
著者Gan, J.H, Wang, Q.Y.
登録日2021-07-04
公開日2022-05-11
最終更新日2022-05-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Xenogeneic nucleoid-associated EnrR thwarts H-NS silencing of bacterial virulence with unique DNA binding.
Nucleic Acids Res., 50, 2022
4CZ0
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BU of 4cz0 by Molmil
Structure of the A_mallard_Sweden_51_2002 H10 Avian Haemmaglutinin in complex with avian receptor analog Su-3SLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HAEMAGGLUTININ, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose, ...
著者Vachieri, S.G, Xiong, X, Collins, P.J, Walker, P.A, Martin, S.R, Haire, L.F, McCauley, J.W, Gamblin, S.J, Skehel, J.J.
登録日2014-04-16
公開日2014-06-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Receptor Binding by H10 Influenza Viruses.
Nature, 511, 2014
6ITA
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BU of 6ita by Molmil
Crystal structure of intracellular B30.2 domain of BTN3A1 mutant
分子名称: Butyrophilin subfamily 3 member A1
著者Yang, Y.Y, Liu, W.D, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H.
登録日2018-11-20
公開日2019-04-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated V gamma 9V delta 2 T Cell Activation.
Immunity, 50, 2019
6WJ0
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BU of 6wj0 by Molmil
Crystal structure of Fab 54-4H03
分子名称: Fab 54-4H03 heavy chain, Fab 54-4H03 light chain, GLYCEROL
著者Wu, N.C, Wilson, I.A.
登録日2020-04-11
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Convergent Evolution in Breadth of Two VH6-1-Encoded Influenza Antibody Clonotypes from a Single Donor.
Cell Host Microbe, 28, 2020
3FIX
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BU of 3fix by Molmil
Crystal structure of a putative n-acetyltransferase (ta0374) from thermoplasma acidophilum
分子名称: 1,2-ETHANEDIOL, N-ACETYLTRANSFERASE
著者Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Clancy, S, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG)
登録日2008-12-12
公開日2009-01-13
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the novel PaiA N-acetyltransferase from Thermoplasma acidophilum involved in the negative control of sporulation and degradative enzyme production.
Proteins, 79, 2011
4YMQ
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BU of 4ymq by Molmil
X-ray co-structure of nuclear receptor ROR-GAMMAT + SRC2 peptide with a benzothiadiazole dioxide inverse agonist
分子名称: 4-{3-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl]-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl}-N-[(2R)-4-hydroxybutan-2-yl]-N-methylbutanamide, GLYCEROL, Nuclear receptor ROR-gamma, ...
著者li, X.
登録日2015-03-07
公開日2015-04-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of 1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide analogs as new RORC modulators.
Bioorg.Med.Chem.Lett., 25, 2015

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