8JV6
Cryo-EM structure of the zebrafish P2X4 receptor in complex with BAY-1797
Summary for 8JV6
| Entry DOI | 10.2210/pdb8jv6/pdb |
| EMDB information | 36669 |
| Descriptor | P2X purinoceptor, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[4-(3-chloranylphenoxy)-3-sulfamoyl-phenyl]-2-phenyl-ethanamide (3 entities in total) |
| Functional Keywords | atp, allosteric modulator, channel, transport protein |
| Biological source | Danio rerio (zebrafish) |
| Total number of polymer chains | 3 |
| Total formula weight | 121996.63 |
| Authors | Hattori, M.,Shen, C. (deposition date: 2023-06-27, release date: 2023-10-18, Last modification date: 2024-04-24) |
| Primary citation | Shen, C.,Zhang, Y.,Cui, W.,Zhao, Y.,Sheng, D.,Teng, X.,Shao, M.,Ichikawa, M.,Wang, J.,Hattori, M. Structural insights into the allosteric inhibition of P2X4 receptors. Nat Commun, 14:6437-6437, 2023 Cited by PubMed: 37833294DOI: 10.1038/s41467-023-42164-y PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.43 Å) |
Structure validation
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